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TOLUENE DIISOCYANATE (80/20 mixture of 2,4- and 2,6- isomers)ICSC: 1783
TDI 80/20
m-Tolylidene diisocyanate
November 2019
CAS #: 26471-62-5
UN #: 2078
EC Number: 247-722-4

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Risk of fire and explosion as a result of decomposition when heated.  NO open flames. NO contact with water.    Use powder, carbon dioxide, water in large amounts.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. Combat fire from a sheltered position. 

 AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS PREVENTION FIRST AID
Inhalation Irritability. Sore throat. Sore throat. Cough. Headache. Nausea. Vomiting. Vomiting. Wheezing. Wheezing. Chest tightness. Chest tightness.  Use appropriate engineering controls.  Fresh air, rest. Half-upright position. Refer immediately for medical attention. 
Skin Redness. Pain. Blisters.  Protective gloves. Protective clothing.  See Notes. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Irritability. Sore throat. Abdominal pain. Nausea. Vomiting.    Rinse mouth. Refer immediately for medical attention. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Special emergency response required. 

According to UN GHS Criteria

skull;toxiccancer;health haz
DANGER
Fatal if inhaled
Causes serious eye irritation
Suspected of causing cancer
Harmful to aquatic life with long lasting effects
May cause an allergic skin reaction
May cause allergy or asthma symptoms or breathing difficulties if inhaled
May cause respiratory irritation 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from food and feedstuffs. Separated from : see Chemical Dangers. Store only in original container. Cool. Keep in a well-ventilated room. Store in an area without drain or sewer access. Refer to the manufacturer's instructions for proper storage conditions. 
PACKAGING
Do not transport with food and feedstuffs. 
TOLUENE DIISOCYANATE (80/20 mixture of 2,4- and 2,6- isomers) ICSC: 1783
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
CLEAR SLIGHTLY YELLOW SOLUTION WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
The substance polymerizes with water and many chemicals in a hazardous way. This generates fire or explosion hazard. On combustion, forms toxic gases. 

Formula: C9H6N2O2
Molecular mass: 174,16
Boiling point at 101.3kPa: 252-255°C
Melting point: 4 - 10°C
Relative density (water = 1): 1.22 (20°C)
Vapour pressure, Pa at 20°C: 1.4 - 1.5
Octanol/water partition coefficient as log Pow: 3.43 (technical grade)
Solubility in water, mg/l at 25°C: 124
Flash point: see Notes
Auto-ignition temperature: 595-598°C (technical grade)
Viscosity: 2.221 mm²/s at 20°C 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
Serious by all routes of exposure. 

Effects of short-term exposure
Inhalation of high concentrations may cause chemical pneumonitis and lung oedema. 

Inhalation risk
A harmful concentration of can be reached (very) quickly. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation may cause asthma. This substance is possibly carcinogenic to humans. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 0,001 ppm as TWA; 0.005 ppm as STEL; (skin); (SEN).
MAK: sensitization of respiratory tract and skin (SAH); carcinogen category: 3A 

ENVIRONMENT
The substance is harmful to aquatic organisms. The substance may cause long-term effects in the aquatic environment. 

NOTES
Decomposes slowly in water or acidic solutions forming carbon disulfide and amines.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
The odour warning when the exposure limit value is exceeded is insufficient.
See ICSC 0339. 

ADDITIONAL INFORMATION
  EC Classification
 

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