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Agricultural chemicals - 1,674 entries found

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CIS 97-1617 Clarke E.E.K., et al.
The problems associated with pesticide use by irrigation workers in Ghana
A study of 123 farm workers on three irrigation project areas in Ghana revealed moderate levels of knowledge of the routes of absorption of pesticides and of potential symptoms following exposure. Knowledge of personal protective measures was poor to moderate. High risk practice included frequent handling of the chemicals, home storage of pesticides, and short-re-entry intervals. The prevalence of symptoms was higher and cholinesterase levels lower than in a control group of teachers. Recommendations include training of agriculture and health workers in safety precautions and in the recognition and management of pesticide-related ill health.
Occupational Medicine, July 1997, Vol.47, No.5, p.301-308. 13 ref.

CIS 97-1529 Illing H.P.A.
Is working in greenhouses healthy? Evidence concerning the toxic risks that might affect greenhouse workers
A review of various sources of information concerning working conditions in greenhouses is presented, with particular reference to the United Kingdom. General health statistics indicate that the most likely health effects of working in greenhouses are immunologic reactions leading to asthma, allergic alveolitis and dermatitis, and irritancy. Epidemiologic studies of greenhouse workers have found evidence of respiratory diseases, carcinogenicity, mutagenicity and reproductive effects. Potential sources of ill-health include plant material, plant diseases and pests, plant protection products and plant extracts. Statistics indicate that the incidence of ill-health among greenhouse workers in the United Kingdom is relatively low.
Occupational Medicine, July 1997, Vol.47, No.5, p.281-293. Illus. 70 ref.

CIS 97-1238 O'Malley M.
Clinical evaluation of pesticide exposure and poisonings
Toxic effects of exposure to a range of pesticides are reviewed: organophosphates and N-methyl carbamates (neurotoxic effects, cholinesterase inhibition, irritation, neuropathy, neurobehavioural effects); pyrethrin and synthetic pyrethroid insecticides (allergic reactions); organochlorine insecticides (neurotoxic effects); fumigants and nematocides (non-specific gastrointestinal, cardiorespiratory and central nervous system effects); and herbicides and dipyridyls (irritation and systemic poisoning following ingestion). Pesticide poisoning treatments are outlined and brief case studies illustrate common acute effects.
Lancet, 19 Apr. 1997, Vol.349, No.9059, p.1161-1166. 51 ref.


CIS 01-318 Restricted Pesticides (Certified User) Regulations, 1996 [Belize]
These Regulations, issued under the authority of thePesticides Control Act, define the procedures for the certification of authorized users of pesticides. Effective date: 15 Aug. 1996.
Government Printery, Laws, Statutes (Belize), 1996, No.112, p.1-9.

CIS 00-816 Berenguer Subils J., Gadea Carrera E.
Sale of dangerous chemicals: Specific measures for pesticides
Comercialización de productos químicos peligrosos: Disposiciones específicas para plaguicidas [in Spanish]
Topics: classification; comment on directive; dangerous substances; data sheet; labelling; legislation; pesticides; Spain; warning notices.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1996. 10p. 21 ref.

CIS 99-1769 Pesticide Registration Regulations 1996 [Nigeria]
Topics: approval; chemical products; compliance tests; law; Nigeria; notification of dangerous substances; penalties; pesticides.
Official Gazette Extraordinary (Nigeria), 18 June 1996, Vol.83, Part B, No.27, Supplement, p.B303-B307.

CIS 99-1075 Order of 28 March 1996 establishing evaluation standards for active components of pesticides for their inclusion in Annex I of Council Directive 91/414/EEC of 15 July, concerning the placing of plant protection products on the market [Spain]
Orden de 28 de marzo de 1996 por la que se establecen normas para la evaluación de sustancias activas de productos fitosanitarios para su inclusión en la lista comunitaria del anexo I de la Directiva 91/414/CEE, del Consejo, de 15 de julio, relativa a la comercialización de los productos fitosanitarios [España] [in Spanish]
For Council Directive 91/414/EEC see CIS 95-1942. Topics: agricultural chemicals; chemical analysis; dangerous substances; evaluation of results; law; pesticides; Spain; warning notices.
Boletín Oficial del Estado, 3 Apr. 1996, No.81, p.12535-12537.

CIS 98-827
International Programme on Chemical Safety (IPCS)
Topics: agricultural chemicals; methomyl; cholinesterase; criteria document; ILO; IPCS; literature survey; pesticide poisoning; poisoning; toxic effects; toxicology; UNEP; WHO.
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1996. 150p. 264 ref. Price: CHF 23.00 (CHF 16.10 in developing countries).

CIS 98-750 Clavel J., Hémon D., Mandereau L., Delemotte B., Séverin F., Flandrin G.
Farming, pesticide use and hairy-cell leukemia
Topics: agriculture; crop protection; epidemiologic study; exposure evaluation; forage crops; France; insecticides; length of exposure; leukaemia; organophosphorus compounds; pesticides; smoking.
Scandinavian Journal of Work, Environment and Health, Aug. 1996, Vol.22, No.4, p.285-293. 35 ref.

CIS 98-234
International Programme on Chemical Safety (IPCS)
Topics: criteria document; ILO; insecticides; IPCS; literature survey; methaemoglobinaemia; toxic effects; toxicology; UNEP; WHO.
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1996. 164p. 352 ref.

CIS 97-1993 Genevini P.L.
Toxicity of sewage sludge - Presence of organic xenobiotic compounds
La tossicità dei fanghi di depurazione, presenza di xenobiotici organici [in Italian]
Sludge from sewage treatment may be used in agricultural fertilizing practices. Levels of organic compounds in sludge may often be rather high, but although classified as highly toxic occupational polluting agents, they are not covered by regulations in all European Union countries. The present compilation shows the levels of these pollutants in soil and water, along with data on biodegradation and uptake by vegetables and animals.
Fondazione Lombardia per l'Ambiente, Foro Bonaparte, Milano, Italy, Dec. 1996. 294p. Illus. Bibl.ref.

CIS 97-2002 Camoni I.
Opinions expressed by the Italian National Advisory Toxicological Committee on some active ingredients of pesticides
Pareri espressi dalla Commissione Consultiva Tossicologica Nazionale su alcuni principi attivi di presidi sanitari [in Italian]
This report presents toxicity evaluations of 30 active ingredients in pesticides. Information is provided on carcinogenic and mutagenic effects and an overall classification is derived. Substances covered: acephate (orthene), acifluorfen, alachlor (lasso), amitraz, asulam, atrazine, bromoxynil, captan, chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile), clofentezine, cypermethrin, dichlobenil (2,6-dichlorobenzonitrile), 1,3-dichlorpropene, dichlorvos, dicofol (kelthane), ethylenbisdithiocarbamates (mancozeb, maneb, metiram (polycarbazine), zineb), folpet, lindane, oxadixyl, oxyfluorfen, permethrin, phosethyl aluminium, phosphamidon, prochloraz, propoxur (arpocarb), terbutryn, tetrachlorvinphos.
Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy, 1996. 142p. Index.

CIS 97-1946 Wesseling C., et al.
Cancer in banana plantation workers in Costa Rica
In this retrospective cohort study workers of Costa Rica banana companies were followed up in the cancer registry between 1981 and 1992: 29,565 men and 4892 women for 407,468 person-years. There was heavy exposure to pesticides, such as dibromochloropropane. 368 cancer cases were identified. Among men, an increased standardized incidence ratio was observed for melanoma and penile cancer; among women, for cervical cancer and leukaemia. Risk estimates for lung cancer were elevated among male workers with the longest period of employment.
International Journal of Epidemiology, Dec. 1996, Vol.25, No.6, p.1125-1131. 23 ref.

CIS 97-1945 Zhong Y., Rafnsson V.
Cancer incidence among Icelandic pesticide users
This cohort study examined cancer risk among 2,449 licensed pesticide users in Iceland. Included were also students from a horticultural college, gardeners, and vegetable farmers. The standardized incidence ratio (SIR) for all cancer sites was 0.80. Among females there was a significant increase in the incidence of cancer of lymphatic and haematopoietic tissues. The overall incidence of rectal cancer was three times the expected value.
International Journal of Epidemiology, Dec. 1996, Vol.25, No.6, p.1117-1124. 38 ref.

CIS 97-1899 Folsom A.R., et al.
Cancer incidence among women living on farms: Findings from the Iowa Women's Health Study
This cohort study, based on a questionnaire survey of 37,148 women living on farms, analyzed site-specific cancer incidence among them. Overall cancer risk was lower than among non-farm residents. One striking finding was the elevated risk of non-Hodgkin's lymphoma in farm residents. Although the aetiology of this disease is unknown, literature data on exposure to herbicides and pesticides do suggest a possible relationship to the disease among women as well as among men.
Journal of Occupational and Environmental Medicine, Nov. 1996, Vol.38, No.11, p.1171-1176. 24 ref.

CIS 97-837 Kross B.C., et al.
Proportionate mortality study of golf course superintendents
A mortality study was carried out among 686 golf course superintendents who died between 1970 and 1992. These workers were exposed to a variety of hazards including pesticides. Results showed a significant excess mortality from smoking-related diseases, including arteriosclerotic heart disease and respiratory diseases such as lung cancer and emphysema. There were also increased levels of brain cancer, non-Hodgkin's lymphoma, cancer of the large intestine, prostrate cancer and diseases of the nervous and sensory systems. Preventive strategies such as smoking cessation programmes and precautions for the reduction of pesticide exposure are recommended.
American Journal of Industrial Medicine, May 1996, Vol.29, No.5, p.501-506. 43 ref.

CIS 97-936 Ekström G.
World directory of pesticide control organisations
This directory provides contact details of national authorities in 180 countries which are involved in pesticides and their control. Summary information is provided on national domestic activities performed by competent authorities, research institutions, laboratories, etc. responsible for various aspects of the national government's pesticide control strategy. In addition, centres which act as contact points for international organizations concerned with pesticides are identified. Introductory chapters include a review of the role of United Nations agencies and similar organizations in the control of pesticides, and an outline of appropriate technology for pesticide analysis in developing countries.
Royal Society of Chemistry, Thomas Graham House, Science Park, Milton Road, Cambridge CB4 4WF, United Kingdom, 3rd ed., 1996. v, 520p. 40 ref.

CIS 97-913 Lander F., Ronne M.
Frequency of sister chromatid exchange and haematological effects in glass-houses fumigators exposed to pesticides
Frecuencia del intercambio entre cromátidas hermanas y efectos hematológicos en los fumigadores de invernaderos expuestos a pesticidas [in Spanish]
A cross-sectional study involving 134 glass-houses fumigators exposed to a mixture of pesticides and 157 controls was carried out in order to investigate the genotoxicity and haematotoxicity of the products used. Sister chromatid exchange method (SCE) and blood count were used to evaluate chromosome and haematological alterations. SCE frequency was higher in non-smoking fumigators, as opposed to controls. No difference was found in the haematological profiles of the two groups. The results suggest that occupational exposure to pesticides may have genotoxic effects.
Medicina y seguridad del trabajo, 1996, Vol.43, No.168, p.161-169.

CIS 97-907 Persson B.
Occupational exposure and malignant lymphoma
Review of epidemiologic studies concerning the association between malignant lymphoma and exposures in a number of occupations: woodworking; farming and pesticide use; welding and related occupations; meat workers and veterinarians; and occupations involving exposure to solvents, wood preservatives, hairdyes, and rubber chemicals. The studies indicate that occupational factors, especially exposure to solvents, phenoxy herbicides and wood, play a role in the epidemiology of malignant lymphoma.
International Journal of Occupational Medicine and Environmental Health, 1996, Vol.9, No.4, p.309-321. 119 ref.

CIS 97-931
Health and Safety Executive
Pesticide incidents - Report 1995/96
This report provides information on incidents involving pesticides investigated by the Field Operations Directorate of the Health and Safety Executive between Apr. 1995 and Mar. 1996. 169 incidents were investigated, 82 of which alleged ill health. Recent trends in the nature of the incidents and types of pesticides used are presented, and eight case studies of specific incidents are summarized.
HSE Books, P.O. Box 1999, Sudbury, Suffolk CO10 6FS, United Kingdom, Oct. 1996. 22p. 3 ref.

CIS 97-945
International Programme on Chemical Safety (IPCS)
The WHO recommended classification of pesticides by hazard and Guidelines to classification 1996-1997
Part 1 of this document describes the basis of the WHO system for the classification of pesticides according to their acute risk to health. The classification is based primarily on the acute oral and dermal toxicity to the rat (LD50 values). A table shows LD50 values for each class of pesticide: extremely hazardous, highly hazardous, moderately hazardous, and slightly hazardous. The application of the criteria for classification is explained along with the effects of classification on labelling. Part 2 provides lists of products in the 4 hazard classes and a list of pesticides considered unlikely to present acute hazard in normal use. Further tables are provided for determining the hazard class of a formulation.
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland. 1996. 64p. 66 ref.

CIS 97-554 Muttray A., Padberg F., Jung D., Rohlfing H.R., Schulz M., Konietzko J.
Acute changes in human EEG after exposure to low doses of oxydemeton methyl
Electroencephalographic (EEG) changes were measured in a group of nine farmers after 30min crop spraying using the organophosphate pesticide, oxydemeton methyl. Analysis of blood samples and an estimation of skin contamination indicated that exposure was low; cholinesterase activity remained unchanged. For EEG measurements in the closed eye condition, the spectral power of the β2-band of a higher exposed group (4 farmers) was significantly elevated in comparison to a lower exposed group (7 farmers). Even low exposure to organophosphates may result in characteristic changes in the human EEG without a decrease in cholinesterase activity.
Central European Journal of Occupational and Environmental Medicine, 1996, Vol.2, No.4, p.367-378. 31 ref.

CIS 97-569 Lessenger J.E.
The California pesticide program: Comments from the front lines
The California pesticide safety programme is discussed from the point of view of a physician practising in an agriculture-rich area. The programme has 8 components: mandatory reporting of pesticide illness; tracking of pesticide sales; transportation and use; cholinesterase testing for applicators; integrated pest management; pest control advisers; safety and pest control operator programmes; physician education; pesticide regulation. Key points of each component are discussed and recommendations for improvement are put forward.
Journal of Agromedicine, 1996, Vol.3, No.4, p.57-68. 19 ref.

CIS 97-567 Schecter A.J., Li L., Ke J., Fürst P., Fürst C., Päpke O.
Pesticide application and increased dioxin body burden in male and female agricultural workers in China
Following large-scale spraying of the pesticide sodium pentachlorophenol (Na-PCP) salt over agricultural and lake areas in China in the 1970s, dioxin levels were determined in sprayers or handlers of Na-PCP, and in persons living in sprayed and non-sprayed areas. Blood and breast-milk samples were collected and pooled for dioxin analysis, and samples of lake sediment were analyzed. Levels of polychlorinated dibenzodioxins and dibenzofurans (PCDD/F) in human tissue were found to be low in China compared with more industrialized countries. However, environmental and human tissue samples from sprayed areas had PCDD/F levels and international dioxin toxic equivalent (I-TEQ) levels several times higher than those from non-sprayed areas.
Journal of Occupational and Environmental Medicine, Sep. 1996, Vol.38, No.9, p.906-911. 10 ref.

CIS 97-236 Hallier E.
Occupational medicine studies of the problems caused by fumigation with methyl bromide
Arbeitsmedizinische Untersuchungen zur Problematik der Durchführung von Begasungen mit Methylbromid [in German]
Methyl bromide is used in the food industry, agriculture and forestry as a pesticide, herbicide and disinfectant. Exposure levels during the fumigation of buildings and soil in greenhouses with methyl bromide were measured. In addition, the effects of methyl bromide on human tissue were studied in in vitro experiments. Blood samples from three cases with acute methyl bromide poisoning in France were analyzed. Based on the results, a new method for medical supervision was developed. This method relies on the analysis of protein adducts in blood samples.
Verlag Dr. Markus Hänsel-Hohenhausen, 63324 Egelsbach, Germany, 1996. 146p. Illus. 138 ref. Price: DEM 70.00.

CIS 97-252
Ausschuss für Gefahrstoffe
Safety rules on harmful substances TRGS 523: Pesticides with very toxic, toxic or health impairing substances or composition
Technische Regeln für Gefahrstoffe TRGS 523: Schädlingsbekämpfung mit sehr giftigen, giftigen und gesundheitsschädlichen Stoffen und Zubereitungen [in German]
Safety rules TRGS 523, which came into effect in Germany in early 1996, provide a list of safe practices for the utilization of harmful pesticides. These rules concern the use of pesticides in health services, livestock rearing, crop protection, food and feed protection and the fumigation of buildings. The personal protective equipment needed for different types of pesticide applications such as spraying, atomizing and coating is outlined. Persons assigned for this kind of work must be properly trained. In Germany, only persons who passed an examination are allowed to carry out the job.
Bundesarbeitsblatt, Mar. 1996, No.3, p.79-84.

CIS 97-244 Bonderf J., Delemotte B.
Nitrate fertilizers: Hazards and their prevention
Engrais azotés. Risques. Prévention [in French]
Information note. If nitrate fertilizers are used under unsatisfactory conditions, they can present a risk to the farmer, the consumer and the environment. Principal hazards affecting the user: ammonia (eyes, skin, respiratory and digestive system); nitrous fumes (asphyxia in farm labourers, lung damage (silo filler's disease), chronic lung disease, dental caries).
Encyclopédie médico-chirurgicale, Toxicologie-Pathologie professionnelle, 2nd Quarter 1996, No.111, 4p. 20 ref.

CIS 97-253 A guide to the safe use of agrichemicals in forestry
This guide identifies hazards associated with the use of agrichemicals in forestry and outlines control measures. The focus is on the use of hand sprayers. Contents: responsibilities of employers and others (safety programme, provision of training); chemical hazards (provision of information, protective clothing and equipment, washing facilities, spills and emergencies); site hazards; checklist.
Occupational Safety and Health Service, Department of Labour, P.O. Box 3705, Wellington, New Zealand, Oct. 1996. 23p. Illus. 1 ref.

CIS 97-163 Jensen S.
Experience from activities in the Third World to improve the knowledge and ability to determine chemical hazards
Problems associated with the expanding use of toxic chemicals in developing countries are examined, with particular reference to the need to establish chemical analysis laboratories in these countries. The use of pesticides, in particular DDT, is discussed and the need to test all new pesticides in the country in which they will be used is emphasized. Problems arising from inadequate infrastructure and lack of educated manpower in developing countries are discussed and recommendations for setting up a chemical laboratory are put forward.
Science of the Total Environment, Sep. 1996, Vol.188, Suppl.1, p.S101-S105.

CIS 97-191 Pimentel D.
Green revolution agriculture and chemical hazards
Health and environmental problems associated with the extensive use of fertilizers and pesticides in agriculture are discussed, with particular reference to developing countries. Contents: extent of use of pesticides and crops treated; health and environmental effects of pesticide exposure (food contamination, pesticide poisoning, antifertility effects, neurotoxic effects); extent of use of fertilizers; health and environmental effects of exposure to nitrogen-containing fertilizers. The need for government policies to protect public health and the environment is emphasized.
Science of the Total Environment, Sep. 1996, Vol.188, Suppl.1, p.S86-S98. 93 ref.

CIS 97-190 Koh D., Jeyaratnam J.
Pesticides hazards in developing countries
Pesticide exposure and associated health hazards in developing countries are reviewed. Types of pesticides and their acute toxic effects are described and the extent of acute pesticide poisoning is estimated. Factors contributing to poisoning include lack of suitable protective clothing, poor knowledge and understanding of safe practices, use of excess pesticide concentrations, and inadequate maintenance of equipment. The need for a control programme is emphasized, and the responsibilities of governments, the agrochemical industries and international agencies are outlined.
Science of the Total Environment, Sep. 1996, Vol.188, Suppl.1, p.S78-S85. 21 ref.

CIS 97-189 Ondieki J.J.
The current state of pesticide management in Sub-Saharan Africa
Topics covered in this review include: pesticide usage in Sub-Saharan Africa; health and environmental concerns (poisoning, wildlife contamination); pesticide regulation and legislation; the need for alternative pest control strategies (integrated pest management). Recommendations include those for the training of farmers and other users in the correct handling and use of pesticides, and strengthening of regulatory controls.
Science of the Total Environment, Sep. 1996, Vol.188, Suppl.1, p.S30-S34. 16 ref.

CIS 96-2190 Gadon M.
Pesticide poisonings in the lawn care and tree service industries
28 cases of suspected or confirmed pesticide poisonings among lawn care and tree service workers reported to the New York State Pesticide Poisoning Registry from 1990 to 1993 are reviewed. The most common classes of pesticide applied were organophosphates (71%) and herbicides (43%). Approximately 70% of the affected workers experienced some symptoms around the time of exposure, in particular, neuromuscular symptoms. 19 of the 24 workers tested had significant depression of serum cholinesterase activity. Data suggest that exposure was not completely controlled by use of protective measures, possibly because of inadequate training or poor compliance with training procedures.
Journal of Occupational and Environmental Medicine, Aug. 1996, Vol.38, No.8, p.794-799. 12 ref.

CIS 96-2205 Hoekstra E.J., Kiefer M., Tepper A.
Monitoring of exposure to benomyl in nursery workers
Urinary levels of the metabolite methyl-5-hydroxy-2-benzimidazole carbamate (5-HBC) were measured in 10 workers exposed to the fungicide benomyl at 5 nurseries. Environmental exposures were evaluated from gloves, body patches, and air samples were collected with area and personal monitors. The median concentration of 5-HBC for the exposed workers was 23.8µmol per mole of creatinine; no 5-HBC was detected in 9 unexposed controls. Weighing, mixing and application activities involved the highest exposures. Dermal contact appeared to be the primary route of exposure.
Journal of Occupational and Environmental Medicine, Aug. 1996, Vol.38, No.8, p.775-781. 18 ref.

CIS 96-2177 Koch P.
Occupational allergic contact dermatitis and airborne contact dermatitis from 5 fungicides in a vineyard worker - Cross-reactions between fungicides of the dithiocarbamate group?
In February 1995, a case of a vineyard worker with occupational contact dermatitis due to sensitization to mancozeb and perhaps metiram was reported. Patch testing showed strong allergic reactions to two of the commercially available preparations used. Further patch tests showed allergic reactions to mancozeb (0.5 and 1% pet.), a weak reaction to metiram (1% pet.), as well as to four other fungicides of the dithiocarbamate group (maneb, nabam, propineb and zineb), which had never been used in the vineyard.
Contact Dermatitis, May 1996, Vol.34, No.5, p.324-329. 36 ref.

CIS 96-2169 Petrelli G., Mucci N., Siepi G., Pace F.
Assessment of agricultural pesticides for potential carcinogenicity, mutagenicity and reproductive toxicity
Antiparassitari agricoli valutati per potenziali effetti cancerogeni, mutageni e tossico-riproduttivi [in Italian]
The aim of this study was to present a review of core information issued by Italian and international sources on the toxicity of pesticide products used in Italy. A comprehensive table on the carcinogenic, mutagenic and anti-fertility effects of active ingredients and their concentration ranges in commercially available products, as given by the Commissione Consultiva Tossicologica Nazionale (CCTN, an Italian toxicological agency), the European Union, the US Environmental Protection Agency (EPA) and the International Agency for Research on Cancer (IARC), together with CAS numbers, is presented. This information can be useful for the carrying out of risk assessments of the listed pesticides and their solvents in occupationally exposed populations.
Medicina del lavoro, Mar.-Apr. 1996, Vol.87, No.2, p.110-121. 23 ref.

CIS 96-2165 Neuberger J.S.
Atrazine and/or triazine herbicides exposure and cancer: An epidemiologic review
Ten case studies concerning exposure to atrazines and/or triazines and cancer in occupational (agricultural) settings are summarized. Based on the limited data available, there is no convincing evidence of a causal association between atrazine and/or triazine and colon cancer, soft tissue sarcoma, Hodgkin's disease, multiple myeloma or leukaemia. There is a suggestion of a possible association between these compounds and ovarian cancer and non-Hodgkin's lymphoma. While animal studies indicate that atrazine is a potential human carcinogen, current epidemiologic evidence is not conclusive.
Journal of Agromedicine, 1996, Vol.3, No.2, p.9-30. 18 ref.

CIS 96-1440 INCHEM
This CD-ROM contains 9 full-text databases containing chemical safety information: Environmental Health Criteria (EHC) monographs published by WHO (up to: EHC 166, methyl bromide); Health and Safety Guides from the WHO (19 substances); International Chemical Safety Cards (ICSCs), published by IPCS and the European Union (ca. 700 substances); Pesticide Data Sheets (PDSs), prepared by the WHO and the FAO (80 pesticides); Poisons Information Monographs (PIMs), prepared by poisons information centres and toxicologists from around the world (29 common poisonous substances); Joint Expert Committee on Food Additives (JECFA) monographs and evaluations (ca. 900 food additives); IPCS/EC Evaluation of Antidotes Series (major review papers on antidotes to cyanide and paracetamol, as well as on naloxone, flumazenil and dantrolene as antidotes); list of exposure limits for chemicals in major countries, produced by CIS (update of the ILO document abstracted as CIS 91-575, with an additional list of "major hazard" substances with synonyms/trade names and corresponding EEC numbers; the countries are: Australia, Belgium, Czechoslovakia, Denmark, Finland, France, Germany, Hungary, Japan, Poland, Sweden, Switzerland, UK, USA - ACGIH and OSHA, USSR); CIS chemical information (summary of information from other databases, with references to CISDOC; 20 substances).
Canadian Centre for Occupational Health and Safety (CCOHS), 250 Main Street East, Hamilton Ont., L8N 1H6, Canada; International Programme on Chemical Safety (IPCS), World Health Organization, 20 ave. Appia, 1211 Genève 27, Switzerland, 1996. CD-ROM + User's manual (50p. Illus. Index). Bibl.ref.

CIS 96-1438
Health and Safety Executive
Guidance on storing pesticides for farmers and other professional users
This information sheet provides guidance on estimating the size requirements of a pesticide store, selection of a suitable location, design and construction of structures resistant to fire and leakage, organization of the store, provision of warning signs, and use of mobile storage. Additional precautions are given for moisture-activated gassing compounds and oxidizing agents.
HSE Books, P.O. Box 1999, Sudbury, Suffolk CO10 6FS, United Kingdom, 1996. 4p. Illus. 5 ref.

CIS 96-1391 Bukowski J., Brown C., Korn L.R., Meyer L.W.
Prevalence of and potential risk factors for symptoms associated with insecticide use among animal groomers
In a survey of animal groomers and pet-animal veterinarians in New Jersey, USA, approximately 36% of respondents indicated that during the 1994 flea season, they had experienced at least one of 17 symptoms associated with insecticide application. Most frequently reported were central nervous system symptoms (headache, dizziness, confusion) and skin symptoms (skin rash, numbness/tingling). Potential risk factors were identified as number of applications per season, years as an applicator, certain hygiene variables (washing hands and showering within 8 hours), certain classes of products, and status of applicator (veterinary or nonveterinary).
Journal of Occupational and Environmental Medicine, May 1996, Vol.38, No.5, p.528-534. 16 ref.

CIS 96-1187 Pesticides Control Act, 1996 [Seychelles]
This Law regulates the manufacture, distribution, use, storage and disposal of pesticides. Contents: establishment and duties of the Pesticide Board; control of pesticides; enforcement. In annex: list of registered pesticides; labelling requirements (including WHO classification and hazards); scheduled operations (i.e. operations subject to control).
Seychelles Official Gazette, Supplement, 25 Mar. 1996, p.29-54.

CIS 96-530 Handling pesticides
Manejo de plaguicidas [in Spanish]
Contents of this video: definition of pesticides; recommendation for use; how they enter the human organism; transport and storage; preparation and application; what to do in the case of poisoning.
Instituto Nacional de Seguridad e Higiene en el Trabajo, ediciones y Publicaciones, C/ Torrelaguna, 73-28027 Madrid, Spain. PAL videotape (16min). Price: ESP 3000 + VAT. ###

CIS 96-948 Foster R., Knake E., McCarty R.H., Mortvedt J.J.
Weed control manual
The main part of this manual consists of a directory of herbicides commercially available in the US, with guidance on their use, toxicity and protective clothing requirements. Products are arranged by crop to be protected: field corn, soybeans, cotton, small grains, other field crops, vegetables, fruits and nuts, lawns and turf, and aquatic uses. An introductory section provides an overview of weed identification and management, types of pesticide formulations available, environmental aspects and regulatory compliance.
Meister Publishing Company, 37733 Euclid Avenue, Willoughby, OH 44094-5992, USA, 30th ed., 1996. 538p. Illus. Indexes. Price: USD 54.00.


CIS 02-1554 o-Phthalodinitrile
o-Phtalodinitril [in German]
Intoxications following percutaneous absorption and dust inhalation have been reported. Symptoms, which were delayed, included dizziness, nausea, vomiting, headache, sudden unconsciousness and convulsive attacks. Irritation of the skin and mucous membranes have been observed. Animal experiments show toxicity upon acute oral exposure, as well as intraperitoneal and subcutaneous administration.
Berufsgenossenschaft der chemischen Industrie, Postfach 10 14 80, 69004 Heidelberg, Germany, June 1995. 31p. 35 ref.

CIS 02-1549 p-Chlorobenzotrifluoride
p-Chlorobenzotrifluorid [in German]
The olfactory threshold of p-chlorobenzotrifluoride (synonym: 1-chloro-4-trifluoromethylbenzene) is at 0.27mg/m3. Animal experiments show low acute oral and dermal toxicity. Target organs are the kidneys. Subchronic inhalation indicates changes in red cell counts and functional disturbances of the central nervous system. Results of in vitro tests on cells indicate a possible weak genotoxic activity. No reproductive effects have been found.
Berufsgenossenschaft der chemischen Industrie, Postfach 10 14 80, 69004 Heidelberg, Germany, June 1995. 27p. 40 ref.

CIS 99-1772 Registered and restricted pesticides (Registration) Regulations, 1995 [Belize]
Topics: approval; Belize; control of issue of dangerous materials; hazard identification; labelling; law; notification of dangerous substances; pesticides.
Government Printery, Laws, Statutes (Belize), 1995, No.77, p.1-18.

CIS 99-1074 Order of 11 Dec. 1995 regulating the authorization of tests and experiments on pesticides [Spain]
Orden de 11 de diciembre de 1995 por la que se establecen las disposiciones relativas a las autorizaciones de ensayos y experiencias con productos fitosanitarios [España] [in Spanish]
This Act transposes into national legislation the requirements of Council Directive 93/71/EEC concerning information to be submitted for authorizations and "efficacy data" for the placing of plant protection products on the market (CIS 95-1942). Topics: agricultural chemicals; approval; chemical analysis; crop protection; dangerous substances; evaluation of results; law; pesticides; Spain; warning notices.
Boletín Oficial del Estado, 19 Dec. 1995, No.302, p.36235-36252.

CIS 99-255
International Programme on Chemical Safety (IPCS)
Brodifacoum health and safety guide
This document provides practical guidance on the application of exposure limitation guidelines contained in Environmental Health Criteria 175 on anticoagulant rodenticides (CIS 98-799). Includes a summary of chemical safety information for workplace display. Topics: acute poisoning; blood coagulation disorders; brodifacoum; containment of spills; delayed effects; disposal of harmful waste; fire protection; first aid; haemorrhage; health engineering; health hazards; IPCS; irritants; legislation; permissible levels; rodenticides; skin absorption; storage; toxic effects.
World Health Organization (WHO), Distribution and Sales Service, 1211 Genève 27, Switzerland, 1995. 25p. Illus. 6 ref. Price: CHF 5.00 (CHF 3.50 in developing countries).

CIS 99-254
International Programme on Chemical Safety (IPCS)
Bromadiolone health and safety guide
This document provides practical guidance on the application of exposure limitation guidelines contained in Environmental Health Criteria 175 on anticoagulant rodenticides (CIS 98-799). Includes a summary of chemical safety information for workplace display. Topics: acute poisoning; blood coagulation disorders; Bromadiolone; containment of spills; delayed effects; disposal of harmful waste; fire protection; first aid; haemorrhage; health engineering; health hazards; IPCS; legislation; permissible levels; rodenticides; skin absorption; storage; toxic effects.
World Health Organization (WHO), Distribution and Sales Service, 1211 Genève 27, Switzerland, 1995. 25p. Illus. 5 ref. Price: CHF 5.00 (CHF 3.50 in developing countries).

CIS 98-1413
International Programme on Chemical Safety (IPCS)
Methomyl - Health and safety guide
Topics: agricultural chemicals; methomyl; containment of spills; disposal of harmful waste; fire protection; first aid; health engineering; health hazards; IPCS; legislation; neurological effects; permissible levels; storage; toxic effects.
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1995. 28p. Illus. 19 ref. Price: CHF 5.00 (CHF 3.50 in developing countries).

CIS 98-1412
International Programme on Chemical Safety (IPCS)
Warfarin - Health and safety guide
Topics: blood coagulation disorders; containment of spills; disposal of harmful waste; fire protection; first aid; health engineering; health hazards; IPCS; legislation; permissible levels; rodenticides; storage; warfarin.
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1995. 24p. Illus. 11 ref. Price: CHF 5.00 (CHF 3,50 in developing countries).

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