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Agricultural chemicals - 1,674 entries found

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CIS 85-748 Letz G.A., Pond S.M., Osterloh J.D., Wade R.L., Becker C.E.
Two fatalities after acute occupational exposure to ethylene dibromide
2 workers collapsed and subsequently died after entering without protective equipment a storage tank containing residues of ethylene dibromide (EDB). The toxic effects included acute kidney and liver failure, metabolic acidosis and necrosis of the skeletal muscle. Deaths occurred despite intensive medical care, demonstrating the extreme hazards of exposure to EDB.
Journal of the American Medical Association, 2 Nov. 1984, Vol.252, No.17, p.2428-2431. 17 ref.

CIS 85-797 Siewierski M.
Determination and assessment of pesticide exposure
The 16 papers presented at this working conference (29-31 Oct. 1980, Hershey, Pennsylvania, USA) under the 4 section headings: exposure assessment overview; occupational and public health aspects of pesticide exposure; techniques for assessing pesticide exposure; equipment and systems modification for reducing pesticide exposure, are reproduced. Topics covered: role of exposure data in pesticide decision-making; exposure data for risk assessment; applicator exposure studies; extraneous pesticide exposure; safe use practices; protective apparel; epidemiologic concerns; chemical methods for exposure assessment; dermal and inhalation studies; airborne residues; assumptions; closed systems for mixing and loading; droplet-size control in sprayer systems; on-target application of herbicides; controlled release pesticide formulations; flying flagmen system.
Elsevier Science Publishers B.V., P.O. Box 211, 1000 AE Amsterdam, Netherlands, 1984. 222p. Illus. Bibl. Price: US$75.00; Glds.195.00.

CIS 85-502 Garå A.
Pesticide exposure in connection with berry farming
Bekämpningsmedelsexponering i samband med bärodling [in Swedish]
The exposure of 16 strawberry and black-current farmers to various pesticides was studied. The pesticide concentrations measured in the air during spraying were in the range of 1-10µg/m3 but were higher when the spray equipment was being filled. Power preparations yielded considerably higher concentrations than liquid ones (the highest difference observed was by a factor of 200). The biological uptake of pesticides was very low. Blood monitoring carried out before and after work revealed no lowering of enzyme activity. Some changes in pesticide packing and formulation are proposed. A throw-away overall and respirator should be worn by persons handling and formulating pesticides.
Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1984. 27p. 18 ref.

CIS 85-498 Suskind R.R., Hertzberg V.S.
Human health effects of 2,4,5-T and its toxic contaminants
A clinical epidemiological study was conducted on a population consisting of 204 white males exposed to the herbicide 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) and contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin, as a result of employment in the production of 2,4,5-T between 1948 and 1969, and 163 white males currently or formerly employed at the same plant but never associated with production or maintenance functions. In the exposed group clinical evidence of chloracne persisted in 55.7%, but none was found among unexposed workers. Persistence of chloracne was also associated with the presence and severity of actinic elastosis of the skin. An association was found between exposure and the history of gastrointestinal tract ulcer. Among smokers, pulmonary function values were lower among exposed workers than among unexposed workers. An evidence was found of increased risk for cardiovascular disease, hepatic disease, renal damage or central or peripheral nervous system problems.
Journal of the American Medical Association, 11 May 1984, Vol.251, No.18, p.2372-2380. 42 ref.

CIS 85-188 Hearn S., Ott M.G., Kolesar R.C., Cook R.R.
Mortality experience of employees with occupational exposure to DBCP
Mortality experience was examined in a cohort of 550 employees involved in production and formulation of 1,2-dibromo-3-chloropropane from 1957 to 1976. 35 deaths were observed compared with 39.2 expected, through 1979. No statistically significant excess was observed for any cause of death, and no cancer deaths were associated with the stomach, liver, kidney, testes, or skin. 5 lung cancer deaths were observed, compared with 2.7 expected, and 2 of these were in a sub-group directly exposed for ≥1year. Aside from arsenicals exposure, potential confounding resulting from smoking or multiple chemical exposures could not be evaluated.
Archives of Environmental Health, Jan.-Feb. 1984, Vol.39, No.1, p.49-55. 22 ref.

CIS 85-186 Degraeve N., Chollet M.C., Moutschen J.
Genetic and cytogenetic effects of fenitrothion
Mice were injected intraperitoneally with a 1g/kg dose of the organophosphorus insecticide fenitrothion. No increase in the percentage of chromosome aberrations was observed in bone marrow cells and spermatogonia. A dominant lethal mutation assay did not show any enhancement of foetal mortality before or after implantation.
Archives of Environmental Health, Jan.-Feb. 1984, Vol.39, No.1, p.24-26. 13 ref.

CIS 85-35 Confined space entry - hazardous gases
This data sheet intended for farm workers covers all the hazards of work related to silos, grain bins, liquid manure and chemical fertiliser tanks and the measures necessary to prevent accidents. The hazards from gases encountered in farm work are explained (hydrogen sulfide, carbon monoxide, ammonia, methane, nitrogen dioxide).
Manitoba Workplace Safety and Health Division, Suite 1000, 330 St. Mary Ave., Winnipeg, Manitoba R3C 3Z5, Canada, 1984. 11p.

CIS 85-183 Fertilizers
This data sheet intended for farm workers describes the hazards from and safe handling of dry and liquid chemical fertilisers and animal manure.
Manitoba Workplace Safety and Health Division, Suite 1000, 330 St. Mary Ave., Winnipeg, Manitoba R3C 3Z5, Canada, 1984. 7p.

CIS 84-2017 Technical and health regulations regarding the production, marketing and use of pesticides in Spain
Reglamentación técnico-sanitaria para la fabricación, comercialización y utilización de plaguicidas [in Spanish]
This regulation published in the Boletín Oficial del Estado of 24 Jan. 1984 (No.20) defines the rules governing the manufacture, transportation, labelling and packaging, toxicity classification, registration of products and means of preventing exposure during the handling of pesticides.
Salud y trabajo, May-June 1984, No.43, p.58-68. Illus.

CIS 84-2012 Nigg H.N., Stamper J.H., Queen R.M.
The development and use of a universal model to predict tree crop harvester pesticide exposure
This simple regression model is designed to predict the transfer of residual pesticide on tree leaves to the body of a Florida citrus harvester. The model is dependent on work rate and residue concentration. Eventual metabolite output in worker urine is also predicted.
American Industrial Hygiene Association Journal, Mar. 1984, Vol.44, No.3, p.182-186. 12 ref.

CIS 84-2011 Palmgren M.S., Lee T.C.
Malathion and diazinon levels in grain dust from New Orleans area grain elevators
Residual levels of malathion and diazinon were measured in 31 samples of grain dust collected from 6 grain elevators. The analytical limits of detection were 0.1µg/g for malathion and 0.01µg/g for diazinon. Malathion was detected in the dust samples at levels ranging from 0.17 to 32µg/g, but diazinon levels were below the detection limit.
American Industrial Hygiene Association Journal, Mar. 1984, Vol.45, No.3, p.168-171. 11 ref.

CIS 84-1900
(Institut national de recherche et de sécurité)
Chloralose [in French]
Synonyms, use, physical and chemical properties; storage; methods of detection and determination in air; pathology and toxicology: experimental toxicity, metabolism, toxicity in man (poisoning only through the digestive tract, effects vary with the dose). Reference to French OSH legislation, mostly relating to the agricultural use of chloralose, and to French and international transportation regulations. Technical and medical recommendations.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 3rd quarter 1984, No.116, p.419-422. 13 ref.

CIS 84-1712 Libich S., To J.C., Frank R., Sirons G.J.
Occupational exposure of herbicide applicators to herbicides used along electric power transmission line right-of-way
Occupational exposures to herbicides were measured among 12 applicators in 1979 and 24 applicators in 1980, who were applying the three herbicides 2,4-D, dichloroprop and picloram to electric power transmission rights of ways. Dermal absorption was the major absorption route being up to 50 times greater than exposure by the inhalation route when using a hand gun sprayer. Even with the mist blower herbicide application method, dermal absorption was 4 and 11 times greater than exposure by the inhalation route. Worker education on hazards of skin contact and improved protective equipment significantly reduced the 1980 urine concentrations of herbicide residues. A model is presented to relate the urinary concentrations to equivalent daily exposure levels.
American Industrial Hygiene Association Journal, Jan. 1984, Vol.45, No.1, p.56-62. 6 ref.

CIS 84-1599
(Institut national de recherche et de sécurité (France))
Aminotriazole [in French]
Synonyms, uses, physical and chemical properties, detection and determination methods in air, fire hazards, pathology and toxicity in animals and in man (acute, subacute; chronic, mutagenicity, carcinogenicity, teratogenicity, metabolism). In the US, aminotriazole is classified with industrial substances suspected of causing cancer in man; the ACGIH recommends that worker exposure be rigorously maintained at levels that human and animal experiments have shown to be not dangerous. Regulations in effect in France for the protection of the workplace, for agricultural use, and French and international regulations for transportation. Technical and medical recommendations.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 2nd quarter 1984, No.115, p.271-274. 23 ref.

CIS 84-1709
(Jord- och skogsbruksministeriet)
Ordinance on pesticides
Förordning om bekämpningsmedel [in Swedish]
This ordinance (effective: 1 Mar. 1984), published in accordance with the Law on Pesticides dated 23 May 1969 (modified 10 Feb. 1984), institutes a Pesticide Inspection Commission. This commission will be charged with controlling and evaluating the toxicity of pesticides before they are marketed. Chapters on: procedures for requesting registration of pesticides; contents of the pesticide registry; packaging in which pesticides can be sold and appropriate information to be given on the packaging; transport, storage and trade; use of pesticides; products treated with pesticides.
Suomen asetuskokoelma - Finlands författningssamling, 24 Feb. 1984, No.211, p.442-445.

CIS 84-1399 Tanaka S., Lucas J.B.
Dermatitis in paperhangers
A questionnaire survey of 211 members of a paperhangers' union elicited 25 reports of work-related dermatitis. The composition of the paste used by these workers was learned from the manufacturer, and the components of the paste were patch-tested on 11 of the workers who had reported skin lesions. Three of the paste constituents gave positive patch tests in at least one of the workers: chloromethoxypropyl mercuric acetate, 2-((hydroxymethyl)amino)ethanol, and polyethylene glycol monolauroyl ester, an antifoaming agent. The first 2 compounds, both biocides, are capable of decomposing to give formaldehyde, which is thus also a potential sensitiser.
Contact Dermatitis, Jan. 1984, Vol.10, No.1, p.54-55. Illus. 3 ref.

CIS 84-1414 Eriksson K.
Exposure to organophosphorus-based pesticides during their spraying in orchards
Exposition för bekämpningsmedel med en organisk fosforförening som aktiv substans, vis besprutning av fruktodlingar [in Swedish]
Report of an study of workers who spray (from tractors) insecticides with the active ingredients pyrazophos and azinphosmethyl. Summary: toxic effects of the 2 compounds; toxicologic information (enzyme inhibition, paths of entry, occupational hygiene); description of the spraying technique; sampling and analytical techniques; biological monitoring of exposed workers; analysis in air and blood; results and discussion. Measures to reduce exposure.
Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1984. 28p. 14 ref.

CIS 84-1413 Brundin A.
Exposure to captan during its use in spraying in orchards
Exponering för Captan i samband med besprutning av fruktodlingar [in Swedish]
Study of exposure to captan during its use in the spraying of apple trees from tractors. Summary: sampling and analysis of captan in air; biological monitoring of exposed workers; spraying techniques; analysis by high-pressure liquid chromatography; calculation of the external standard; toxicity and physical properties of captan; choice of the most suitable solvent; calculation of inhaled dose; results and discussion.
Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1984. 19p. Illus. 5 ref.

CIS 84-1290 Commission Directive of 18 April 1984 adapting Council Directive 78/631/EEC on the approximation of the laws of the Member States relating to the classification, packaging and labelling of dangerous preparations (pesticides)
Directive du 18 avril 1984, portant adaptation de la directive 78/631/CEE du Conseil concernant le rapprochement des dispositions législatives, réglementaires et administratives relatives à la classification, l'emballage et l'étiquetage des préparations dangereuses (pesticides) [in French]
Update of the list of active substances, subdivided by class and subclass (directive number and nomenclature according to Directive 67/548/EEC, see (CIS 79-1069), and the list of active substances with an indication of the conventional LD50 and LC50 values.
Official Journal of the European Communities - Journal officiel des Communautés européennes, 30 May 1984, No.L 144, p.1-9.

CIS 84-1103 Dubois G.
Plant protection product index. France, Mediterranean and tropical Africa
Index phytosanitaire. France, Afrique méditerranéenne et tropicale [in French]
Descriptive list of 380 active materials used for crop protection. The 1st part concerns 2000 generic and trade-named products approved under French law; the 2nd part concerns about 1000 pesticides distributed in Africa. The active materials and proprietary products are listed alphabetically under the rubrics: insecticides and acaricides, fungicides, herbicides, mixtures and miscellaneous. Entries in the lists give compositions, properties, trade names, applications, toxicities, and addresses of producers or distributors.
ACTA-Publications, 149 rue de Bercy, 75595 Paris Cedex 12, France, 1984. 20th edition, 452p. Price: FF.64.00.

CIS 84-804 Lorand I.C.H., Souza C.A., Costa F.F.
Haematological toxicity associated with agricultural chemicals in Brazil
Case studies of haematological disease in 4 Brazilian agricultural workers accidentally exposed to organochlorides or organophosphates used as pesticides/herbicides. Such diseases have an increasing incidence in Brazil - in one area, 20 out of 36 cases of bone marrow aplasia related to the use of pesticides/herbicides.
Lancet, 18 Feb. 1984, Vol.1, No.8373, p.404. 6 ref.

CIS 84-408
(Institut national de recherche et de sécurité)
2,4,5-Trichlorophenol and 2,4,6-trichlorophenol
2,4,5-trichlorophénol et 2,4,6-trichlorophénol [in French]
This data sheet contains the various names, uses, physical and chemical properties, methods of detection and determination in air, and fire hazards of these trichlorophenols. Pathology and toxicology: experimental toxicology (acute, subacute and chronic poisoning; research into teratogenic, embryotoxic, mutagenic and carcinogenic effects); toxicity in man (acute and chronic, epidemiology of carcinogenesis). Regulations: OSH (in France), transport (France and international). Technical and medical recommendations.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 1st quarter 1984, No.114, p.131-134. 22 ref.

CIS 84-405
(Institut national de recherche et de sécurité)
Deltaméthrine [in French]
This data sheet contains information on the chemical composition, synonyms, use, physical and chemical properties, detection and determination methods in air, and fire hazards of decamethrin. In more detail: toxicity (acute, subacute and chronic poisoning, with symptoms of digestive, neurologic and respiratory problems); genetic effects (mutagenic, teratogenic and carcinogenic). Regulations: OSH (in France), transport (France and international). Technical and medical recommendations.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 1st quarter 1984, No.114, p.119-122. 15 ref.


CIS 96-1190 Royal Decree of 30 Nov. 1983 approving the technical and health regulation on the manufacturing, sale and use of pesticides [Spain]
Real Decreto 3349/1983, de 30 de nov., por el que se aprueba la Reglamentación Técnico-Sanitaria para la fabricación, comercialización y utilización de plaguicidas [España] [in Spanish]
Contents of this Regulation, effective 23 Feb. 1984: scope (excludes: medicinal, narcotic or radioactive preparations; transportation of pesticides; field tests on pesticides); definitions; classification; approval and official registers; authorization of active substances and maximum limits for residues; requirements for establishments engaged in the manufacturing, storage, sale and application of pesticides and related materials; characteristics of pesticides; packaging; labelling; handling and safety practices; export and import; inspection and control. In annex: safety symbols; indications of hazard with mention of the specific risks involved in the use of a pesticide (R numbers); safety recommendations (S numbers).
Boletín Oficial del Estado, 24 Jan. 1984, No.20, p.1850-1856. Illus.

CIS 89-1809
USSR Committee for UNEP
Chemical safety information sheet. Organophosphorus insecticide. Exposure limit (USSR): MAC = 0.1mg/m3.
Centre for International Projects, GKNT, Moskva, USSR, 1983. 14p. 25 ref.

CIS 89-1797
USSR Committee for UNEP
Phosmet (Phthalophose)
Chemical safety information sheet. Organophosphorus insecticide. Exposure limit (USSR): MAC = 0.3mg/m3.
Centre for International Projects, GKNT, Moskva, USSR, 1983. 20p. 41 ref.

CIS 89-1794
USSR Committee for UNEP
Chemical safety information sheet. Insecticide. Exposure limit (USSR): MAC = 0.05mg/m3.
Centre for International Projects, GKNT, Moskva, USSR, 1983. 14p. 42 ref.

CIS 89-1779
USSR Committee for UNEP
Chemical safety information sheet. Insecticide. Exposure limit (USSR): MAC = 0.1mg/m3.
Centre for International Projects, GKNT, Moskva, USSR, 1983. 18p. 75 ref.

CIS 89-437 TEDP
Bladafum-savupanos; sulfoteppi [in Finnish]
Chemical safety information sheet. Impurity in organophosphorus insecticides. Toxicity: LD50 = 5-14mg/kg; irritates the skin, eyes and mucous membranes; inhibits cholinesterase activity; neurotoxic effects. Mandatory European labelling: T, O, R9, R26, R27, R28, S1, S13, S16, S27, S28, S23, S38, S45.
Register of Safety Information of Chemical Products, National Board of Labour Protection, Box 536, 33101 Tampere, Finland, May 1983. 2p. Original on microfiche.

CIS 89-428
USSR Commission for UNEP
Chemical safety information sheet. Exposure limit (USSR): MAC = 0.5mg/m3. Toxicity: suspected carcinogen.
Centre for International Projects, GKNT, Moskva, USSR, 1983. 16p. 34 ref.

CIS 89-70 Endosulfan
Thiodan-tihenne [in Finnish]
Chemical safety information sheet. Insecticide. Exposure limit (8h): 0.1mg/kg. Toxicity: is absorbed through skin; long term exposure can cause renal and hepatic damage, and eczema. Mandatory European labelling: T, R10, R23, R24, R25, R36, R37, R38, S2, S13, S24, S25, S23, S38, S44.
Register of Safety Information of Chemical Products, National Board of Labour Protection, Box 536, 33101 Tampere, Finland, May 1983. 2p. Original on microfiche.

CIS 88-1438 Arsenic
O arsénio [in Portuguese]
Chemical safety information sheet. Based on Fiche toxicologique No.192-1983 published by the Institut national de recherches en sécurité (see CIS 83-1939).
Prevenção no trabalho, Feb. 1987, No.102, p.16.

CIS 87-67 Safety instructions for the use of ammonium hydroxide as fertiliser
Instruções de segurança para o manuseio e aplicação de aquamonia como fertilizante [in Portuguese]
Identity; properties; transport equipment; storage; handling and application; personal protective equipment; first aid; toxic effects; exposure limits.
Cooperativa central dos produtores de açucar e alcool, Caixa postal 5691, 01014 São Paulo, Brazil, 1983. 5p. Illus.

CIS 86-1044 Dev B., Khan R.R., Agarwal S.N.
Toxicology of pesticides - A bibliography of the work done in India
This bibliography covers work done in India that was published in scientific journals, reports and conference proceedings between 1963 and 1982. The pesticides covered are: chlordane, copper oxychloride, dichlorvos, 2,4-D, endrin, ethylene dibromide, heptachlor, methyl bromide, paraquat, phosphamidon, quinalphos and zineb. Some important pesticides (DDT, HCH, methyl parathion, malathion, aldrin, dimethoate, fenitrothion, thiram and ziram) were excluded because comprehensive bibliographies exist in the data sheets on these compounds that are published by the Centre. An author index is included.
Industrial Toxicology Research Centre, Mahatma Gandhi Marg, Lucknow 226 001, India, Sep. 1983. 42p. 346 ref.

CIS 85-1647 Konasewich D.E., Henning F.A., Wile K.H., Gerencher E.
Chlorophenate wood protection - Recommendations for design and operation
Code of practice on the use of chlorophenols and chlorophenates for protecting lumber against fungi in specialised undertakings in British Columbia, Canada. Aspects covered: the need for wood protection; hazards of chlorophenols and chlorophenates; personnel protection; general practices at wood protection facilities; recommended design features and operating practices; transportation of treated materials; disposal of wastes; summary of legislation.
British Columbia Ministry of Environment, Environment Canada, British Columbia, Canada, Dec. 1983. 90p. Illus. 32 ref.

CIS 85-1702 Pesticides - Training module No.2
Plaguicidas - Módulo de adiestramiento 2 [in Spanish]
This training manual is a Spanish-language adaptation, aimed at Latin America, of the WHO publication "Multilevel course on the safe use of pesticides and on the diagnosis and treatment of pesticide poisoning" (VBC/78.8). The course is to be accompanied by a slide-series, and it covers all the risks of handling and using pesticides.
Centro Panamericano de Ecología Humana y Salud (ECO), Apartado Postal 37-473/06696 - México, D.F., Mexico, 1983. 179p. Price: US$6.00.

CIS 85-1049 Izmirova N., Kalojanova-Simeonova F.
Skin resorption of actellic (O-2-diethylamino-6-methylpyrimidin-4-yl-O,O-dimethyl phosphorothioate) combined with high temperature and humidity
Kožna rezorbcija na aktelik (O,2-dietilamino-6-metil pirimidin 4-il-O,O-dimetil fosforotioat) v săčetanie s visoka temperatura i vlažnost [in Bulgarian]
70µg portions of actellic were applied as alcohol solutions to the skin of greenhouse workers, and the treated areas were washed with alcohol after 30-240min. Actellic absorption was uneven. The initial absorption of the substance by the skin was followed by an increase in its concentration on the skin surface; the surface concentration then decreased a 2nd time. Humidity (80-88%) accelerated absorption, whereas the combination of high temperature (30-31°C) and high relative humidity slowed absorption and decreased the amount taken up.
Problemi na higienata, 1983, Vol.8, p.57-63. Illus. 4 ref.

CIS 85-798 Medved' I.L.
Materials to substantiate the maximum acceptable concentration of Diphenamid in workplace air
Materialy k obosnovaniju predel'no dopustimoj koncentracii difenamida v vozduhe rabočej zony [in Russian]
The acute toxicity of Diphenamid was strongly species-specific: its LD50 was 4700mg/kg for rats and 670mg/kg for mice. Its effects were weakly cumulative. It was poorly absorbed by the skin. It was midly irritant (inflammation of the conjunctiva). Its primary target organ was the liver. A MAC of 5mg/m3 (aerosol + vapour) is proposed.
Gigiena i sanitarija, May 1983, No.5, p.77-78. 3 ref.

CIS 85-499 Kagan Ju.S., Vojtenko G.A., Pan'šina T.N., Voronina V.M., Kokšareva N.V., Rodionov G.A., Sasinovič L.M., Ungvari D., Kadar I., Lehocki K., Molnar E., Pakši K., Seberini Ju., Seberini S., Tatraj Ė.
Investigation of several aspects of the toxicological properties and health effects of the organophosphate pesticide actellic
Kompleksnoe toksikologo-gigieničeskoe issledovanie fosfororganičeskogo insektoakaricida aktellika [in Russian]
In a standard battery of toxicological tests, the acaricide and insecticide actellic showed relatively low toxicity (its LD50 on intragastric administration to rats is 1675mg/kg). It is weakly cumulative on peroral administration or inhalation. The compound is a cholinesterase inhibitor and an inducer of hepatic monooxygenases. It affects neuromuscular and peripheral nerve conduction in animals. On the basis of its threshold for chronic effects, a workplace MAC of 2mg/m3 (vapour and aerosol) is proposed.
Gigiena i sanitarija, June 1983, No.6, p.32-35. 14 ref.

CIS 85-158 Heise H., Mattheus A., Puskeiler T.
Irritant and allergenic effects of the herbicide propachlor
Die irritative und allergisierende Wirkung des herbiziden Wirkstoffes Propachlor [in German]
A review of the literature and report of experiments on the irritant and sensitising effects of N-isopropyl-2-chloroacetanilide (generic name propachlor): animal studies, comparative skin tests, epidemiologic surveys. In addition to irritation and sensitisation, a strong delayed reaction has been observed in humans; 13 days may elapse between exposure and the appearance of eczema. Thus, all skin contact should be avoided during application of herbicides containing propachlor.
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete, 1983, Vol.29, No.11, p.675-677. 13 ref.

CIS 84-1997 Mirkova E., Antov G.
Experimental evaluation of the risk of prenatal pathology due to warfarin, a coumarin rodenticide
Eksperimentalna ocenka na riska ot prenatalna patologija pri văzdejstvie na kumarinovija rodenticid varfarin [in Bulgarian]
The embryotoxic and teratogenic effect of the coumarin preparation warfarin, the active ingredient of the Bulgarian rodenticide formulation Raton, was studied in rats. The prenatal toxicity of the preparation (peroral administration) was determined at doses of 8-0,04mg/kg (LD50 oral for rats, 16mg/kg). Warfarin, at all levels studied, was embryotoxic and teratogenic. It increased the level of embryonal lethality, provoked a characteristic haemorrhagic syndrome in the foetus, induced structural malformations of the hind limbs, internal hydrocephalus and haemorrhages in the brain tissue and abdominal cavity. Measures are proposed for the protection of women working in the production of coumarin rodenticides.
Higiena i zdraveopazvane, Mar. 1983, Vol.26, No.6, p.476-482. Illus. 33 ref.

CIS 84-1956 Popov I., Dărlenski B., Mladenova S.
Occupational dermatoses among agricultural workers in green-house production of vegetables
Professionalni dermatozi sred selskostopanskite rabotnici v oranžerijnoto zelenčukoproisvodstvo [in Bulgarian]
During a prophylactic examination, occupational dermatoses and eczemas were found in 15 (12.93%) of 116 agricultural workers from green-house vegetable production. Occupational contact allergic dermatitis was found in 10. The insecticide Akrex was the most frequent etiological sensitisation factor. Polyethylene gloves are recommended for personal protection.
Higiena i zdraveopazvane, 1983, Vol.26, No.3, p.214-217. 12 ref.

CIS 84-1711
Committee on Work on Plantations (ILO)
Conclusions (No.76) concerning occupational safety and health on plantations
Conclusions (n°76) concernant la sécurité et l'hygiène du travail dans les plantations [in French]
Conclusions adopted by the 8th Session of the committee (Geneva, 7-16 Dec. 1982). Review of the risks to which plantation workers are exposed, particularly in developing countries. Definition of the characteristics of statistical information and of data storage relating to occupational diseases and accidents. Preventive measures with regard to both occupational and transportation accidents. Use of chemical products and labour inspection. Recommendations on international cooperation.
Official Bulletin - Bulletin officiel, 1983, Vol.66, Series A, No.3, p.171-175.

CIS 84-1710 Good workplace practices for the manufacture and formulation of pesticides
This 15min sound tape-slide presentation covers: hazard awareness; emergency response; operating procedures; hygiene practices; control monitoring; training and medical programmes.
National Agricultural Chemicals Association, 1155 Fifteenth Street, N.W., Washington, D.C. 20005, USA, 1983. Price: US$25.00.

CIS 84-1614 Miscellaneous pesticides
Background material and a section on cancer epidemiology of pesticide manufacturers, formulators and users are followed by individual monographs for: chlordimeform; chlorobenzilate; dicofol; malathion; methyl parathion; parathion; piperonyl butoxide; tetrachlorvinphos; trichlorfon; diallate; fluometuron; MCPA; nitrofen; sulfallate; captan; chlorothalonil; o-phenylphenol and its sodium salt; 1-naphthylthiourea.
International Agency for Research on Cancer, 150 cours Albert-Thomas, 69372 Lyon Cedex 2, France, Jan. 1983, Vol.30. 424p. Illus. Over 1500 ref. Index. Price: SF.60.00.

CIS 84-1659 Finkel A.J., Hamilton A., Hardy H.L.
Hamilton and Hardy's industrial toxicology
This textbook covers the diagnosis and control of occupational disease and the toxicology of: metals and metalloids; chemical compounds; organic high polymers; pesticides; dusts. The health hazards of radiant energy are also dealt with.
John Wright PSG Inc., 545 Great Road, Littleton, MA 01460, USA, 1983. 428p. Over 1000 ref. Glossary. Index. Price: US$42.50.

CIS 84-1398 Mathias C.G.T., Andersen K.E., Hamann K.
Allergic contact dermatitis from 2-n-octyl-4-isothiazolin-3-one, a paint mildewcide
A batch maker in a paint manufacturing company developed a recurring dermatitis resembling a poison ivy rash. Patch testing showed the dermatitis to be an allergic response to the title compound, the active ingredient in an anti-mildew component of the paint. Because the compound is highly corrosive, care must be taken in patch testing to avoid false positive tests and inadvertent sensitisation.
Contact Dermatitis, Nov. 1983, Vol.9, No.6, p.507-509. Illus. 9 ref.

CIS 84-1415 Khan R.R., Dev B.
Toxicology data sheets on chemicals: Thiram
This data sheet covers: identifiers, properties and uses; production; toxicity studies (carcinogenicity, mutagenicity, teratogenicity, neurotoxicity, reproduction studies, embryotoxicity, immunotoxicology); phytotoxicity; case reports and epidemiology; residues; degradation; sampling and analysis; legal status (occupational exposure limits, Indian standards, handling, precautionary measures).
Industrial Toxicology Research Centre, Mahatma Gandhi Marg, Lucknow - 226001, India. Apr. 1983. 14p. Illus. 125 ref.

CIS 84-1412 Guidelines for the safe and effective use of pesticides
These guidelines are intended to enhance the training of, and be followed by, those who use pesticides at every stage from purchase to the disposal of empty containers. Contents: choice of pesticide; purchase, storage and transport; formulations, packs, measuring and mixing; use, maintenance and repair of application equipment; pesticide use in the field; precautions; first aid. Major pesticide formulation types and a glossary of terms are appended.
Groupement international des associations nationales de fabricants de produits agrochimiques, avenue Hamoir 12, 1180 Bruxelles, Belgium, May 1983. 58p. Illus. Price: BF.125.00.

CIS 84-1362 Wood S., Rom W.N., White G.L., Logan D.C.
Pentachlorophenol poisoning
5 cases of pentachlorophenol (PCP) poisoning in workers at wood preservative manufacturing plants are described. 2 cases were fatal. All presented fever, severe in 2. An increased anion gap and renal insufficiency occurred in 2. PCP may uncouple oxidative phosphorylation. Hot weather appears to be a predisposing factor, and exposure to PCP should be kept to a minimum during hot periods. Treatment is briefly discussed.
Journal of Occupational Medicine, July 1983, Vol.25, No.7, p.527-530. 26 ref.

CIS 84-1361 Lotti M., Becker C.E., Aminoff M.J., Woodrow J.E., Seiber J.N., Talcott R.E., Richardson R.J.
Occupational exposure to the cotton defoliants DEF and merphos - A rational approach to monitoring organophosphorous-induced delayed neurotoxicity
S,S,S-Tributyl phosphorotrithioate (DEF) and merphos can produce delayed neurotoxicity in animals. Inhibition of the neurotoxic esterase (NTE) in lymphocytes was measured in 7 workers exposed during aerial and ground application of these defoliants in cotton fields, as was peripheral nerve function. The major route of exposure was via the skin. Lymphocyte NTE was affected in exposed workers, according to both intensity and length of exposure. There were no detectable electrophysiological effects. Measurement of NTE in lymphocytes in workers exposed to organophosphates is a rational biomonitor of delayed neuropathy.
Journal of Occupational Medicine, July 1983, Vol.25, No.7, p.517-522. Illus. 45 ref.

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