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Skin diseases - 1,481 entries found

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  • Skin diseases

1987

CIS 89-1304 Van der Willigen A.H., Van Joost T., Stolz E., Van der Hoek J.C.S.
Contact dermatitis to safflower
First report of allergic contact dermatitis due to safflower (Carthamus tinctorius). The victim was an inspector at a flower auction.
Contact Dermatitis, Sep. 1987, Vol.17, No.3, p.184-186. Illus. 7 ref.

CIS 89-1305 Farli M., Ginanneschi M., Francalanci S., Martinelli C., Sertoli A.
Occupational contact dermatitis to N-methylol-chloracetamide
Case report of a 50-year-old male worker in a factory producing plasticine (modeling clay). The agent responsible, a preservative, was identified by patch testing. Transfer of the worker from mixing to other work relieved the problem.
Contact Dermatitis, Sep. 1987, Vol.17, No.3, p.182-184. 11 ref.

CIS 89-1284 Rivers J.K., Rycroft R.J.G.
Occupational allergic contact urticaria from colophony
First report of allergic contact urticaria from colophony (asthma from occupational exposure is well known). The victim was a 34-year-inspector of printed circuit boards.
Contact Dermatitis, Sep. 1987, Vol.17, No.3, p.181. 1 ref.

CIS 89-1303 Kavli G., Angell E., Moseng D.
Hospital employees and skin problems
A total of 1,481 hospital employees answered a questionnaire on atopy, hand eczema, and dry chapped hands. Out of 864 (58.7%) responders, 17% claimed to suffer from hand eczema. There was not significantly more hand eczema among women (17.6%) than men (15.7%). Atopic disposition was present in 17.5% of responders, of whom a significantly higher number (36.4%) claimed to have hand eczema. Dry chapped hands seemed to be a problem in 33.1%, mainly among nurses, assistant nurses and laboratory assistants. Technicians and X-ray assistants (38%) and kitchen workers (35.7%) claimed to suffer significantly more from hand eczema than others. Their working conditions were inspected. Following examination by a dermatologist, irritant contact eczema was diagnosed in 11 of 17, and occupational eczema in 3. None of the janitors or technical workers (all men) had hand eczema.
Contact Dermatitis, Sep. 1987, Vol.17, No.3, p.156-158. 6 ref.

CIS 89-1300 Kavil G., Moseng D.
Contact urticaria from mustard in fish-stick production
At a major fish factory in northern Norway, workers employed in fish-stick and fillet production participated in a survey on skin diseases. 122 (80.1%) of the workers in the fish-stick section responded, but only 60.7% of the fillet workers. Clinical examination and patch testing revealed 16 cases of occupational dermatitis among workers in fish-stick production, 3 of whom had contact urticaria from mustard and 8 from fish. There were only 6 cases found of occupational dermatitis among fillet workers; 3 reacted to fish and 3 had irritant contact dermatitis. Working conditions are described for both locations. A greater exposure to irritants may in part explain the 10.7% occupational dermatitis in the fish-stick section compared to only 3.5% in the fillet section.
Contact Dermatitis, Sep. 1987, Vol.17, No.3, p.153-155. 5 ref.

CIS 89-1283 Olumide Y.
Contact dermatitis in Nigeria - II. Hand dermatitis in men
In a series of 545 consecutive contact dermatitis clinic patients, 274 (50.3%) were men, 56 (20.4%) of whom had hand dermatitis alone, 40 (71.4%) being allergic. The common sensitisers were dichromate in cement, nickel on metal gates, colophony, epoxy resins and rubber chemicals. 48 (85.7%) of the hand cases came from occupational sources. Half of the patch-test-negative men worked in wet jobs. The hands of Nigerian men appear to be less tolerant to irritant wet jobs than those of women, which have the opportunity of becoming hardened from childhood.
Contact Dermatitis, Sep. 1987, Vol.17, No.3, p.136-138. 6 ref.

CIS 89-1228 Watt A.D.
Hairdressers and hepatitis B - A risk of inapparent parenternal infection
According to Scottish statistics for 1981-84, 14 cases of hepatitis B out of 1774 recorded were in hairdressers. This represents an annual incidence rate for the profession of 41 per 100,000, a major increase from the annual incidence rate of 7.79 per 100,000 for the period 1973-80. The possible role of parenteral infection through skin affected by dermatitis is discussed.
Journal of the Society of Occupational Medicine, Winter 1987, Vol.37, No.4, p.124-125. 8 ref.

CIS 89-910 Cyrkunov L.P.
Toxico-allergic dermatitis due to ethylenediamine in herbicide (zineb) production
Toksiko-allergičeskij dermatit ot vozdejstvija ėtilendiamina v proizvodstve gerbicida cineba [in Russian]
Medical examination of a worker with 3 years of exposure to ethylenediamine showed initial signs of allergy after the 1st year. Ethylenediamine possesses irritant and allergenic properties, and contact with it can lead to development of allergic dermatitis and eczema, sometimes in combination with allergic bronchitis and asthma. Delayed diagnosis and continuing contact with ethylenediamine result in spreading of the dermatitis and serious complications.
Gigiena truda i professional'nye zabolevanija, Aug. 1987, No.8, p.45-46. 3 ref.

CIS 88-1877 Dimitrov M.
Role of microscopic fungi and mycotoxins in occupational pathology
Rolja na mikroskopičnite găbi i mikotoksinite v profesionalnata patologija [in Bulgarian]
Dermatotoxicoses and respiratory mycotoxicoses are mainly of occupational origin. The role of moulds in the aetiology of chronic pulmonary diseases is described, the initial allergic reaction being of great importance, followed by a lasting allergic state with added chronic toxic action by the fungi. Data on occupational morbidity in an environment containing mycotoxins are presented.
Higiena i zdraveopazvane, 1987, Vol.30, No.3, p.89-94. 53 ref.

CIS 88-1997 Bojs G., Nicklasson B., Svensson A.
Allergic contact dermatitis to propyl gallate
The antioxidant propyl gallate in a moisturising cream caused an allergic contact dermatitis in a patient previously sensitised to gallates while working in a bakery.
Contact Dermatitis, Nov. 1987, Vol.17, No.5, p.294-298. Illus. 17 ref.

CIS 88-1996 Cronin E.
Dermatitis of the hands in caterers
Hand eczema among 50 caterers was occupational in 47 and endogenous in 3 cases. Irritants were considered more important than sensitisers. There was a corrlation between atopy and sensitisation to type-I but not type-IV allergens. The commonest type-I sensitiser was fish; garlic was the commonest typ-IV sensitiser. 50% dilutions of garlic and of onion in arachis oil were not irritant and seemed effective patch test materials. The prognosis was not good; the hand eczema continued even in some of those who changed their jobs.
Contact Dermatitis, Nov. 1987, Vol.17, No.5, p.265-269. 5 ref.

CIS 88-1995 Bajnova A., Muhtarova M., Mihajlova A., Hristeva V.
New data about occupational risks associated with photocopying
Novi danni za professionalnija risk pri fotokopirane [in Bulgarian]
Thirteen operators were examined for occupational dermatoses necessitating reassignment. The concentration of airborne ozone 60min after setting the machines in operation was 0.15-0.17mg/m3. Attemps to detect airborne selenium were unsuccessful. Pruritis, papulovesicular rashes and occupational contact eczema were established 4-6 months after beginning work. Confirmed contact allergens in 6 of the operators were toner type B, drum-cleaning fluid and fuser oil. Epicutaneous tests of mercury, cobalt, chromium, mercaptobenzothiazole, colophany and Peru balsam were positive. Measures for reducing exposure of the operators to the allergens were put in practice.
Higiena i zdraveopazvane, 1987, Vol.30, No.6, p.32-36. 20 ref.

CIS 88-1563 Foussereau J., Cavelier C.
Irritant dermatitis due to diallyl glycol carbonate monomer
La dermite par irritation au carbonate de diallylglycol monomère [in French]
Information note for occupational physicians. The allyl monomers widely used in the optical industry are sometimes not tolerated by the skin and eyes; this is especially true of diallyl glycol carbonate (DAGC). The toxicity of DAGC and isopropyl percarbonate (IPP) is reviewed. Clinical aspects indlude the irritant properties of mixtures of DAGC and IPP, the risk of contact with the substances as a function of work assignment (before and after polymerisation), frequency of intolerance in exposed workers, description of lesions. Human tests with IPP, DAGC and impurities found in DAGC, and tolerance in animals are reviewed. Diagnosis, prevention and compensation are also discussed.
Documents pour le médecin du travail, 3rd Quarter 1987, No.31, p.223-226.

CIS 88-1600 Zina A.M., Bedello P.G., Cane D., Bunding S., Benedetto A.
Dermatitis in a rubber tyre factory
An outbreak of occupational dermatitis in a rubber tyre factory is reported. An unusual clinical picture was recognised. Patch tests revealed a high sensitisation rate to the mercaptobenzothiazole (MBT) derivative used: 2-(2-4'dinitrophenylthio)benzothiazole. Since tests with MBT mix and dinitrophenol were negative, sensitisation to a contaminant was suspected. Dinitrochlorobenzene, a starting material for manufacture of the dinitrophenylthiobenzothiazole, was traced as the substance responsible.
Contact Dermatitis, July 1987, Vol.17, No.1, p.17-20. 4 ref.

CIS 88-1553 Richards T.B., Gamble J.F., Castellan R.M., Tory Mathias C.G.
Knuckle pads in live-chicken hangers
A study of live-chicken hangers in a poultry processing plant demonstrated a high prevalence of callosities over the knuckles (knuckle pads) of both hands. Knuckle pads were observed in 56% (23/41) of live-chicken hangers, but in no (0/41) workers from other departments. The probable cause was the repeated striking and sliding of the knuckles against metal shackles in which live birds were being placed. Additional medical and ergonomic evaluation would be worthwhile to confirm the probable cause, to determine whether associated tissue disorders are present in the digits of chicken hangers who develop knuckle pads, and to suggest preventive measures.
Contact Dermatitis, July 1987, Vol.17, No.1, p.13-16. 11 ref.

CIS 88-1599 Mathias C.G.T.
Allergic contact dermatitis from a nonbisphenol A epoxy in a graphite fiber reinforced epoxy laminate
An employee of an aircraft engine manufacturing firm developed dermatitis associated with the handling of a graphite-fibre-reinforced epoxy laminate (epoxy prepreg). Patch test investigation demonstrated that the responsible causal agent was the nonbisphenol A epoxy binder 4-glycidyloxy-N, N-diglycidylaniline. A patch test with bisphenol A epoxy from a standard patch test screening series was negative. Subsequent interviews with other employees suggested that a relative lack of awareness of the cutaneous hazards of fibre-reinforced epoxy laminates, compared with liquid epoxy systems, may be an important risk factor for allergic sensitisation to these composite materials.
Journal of Occupational Medicine, Sep. 1987, Vol.29, No.9, p.754-755. 4 ref.

CIS 88-1538 Redmond S.F., Schappert K.R.
Occupational dermatitis associated with garments
An outbreak of irritant contact dermatitis associated with residual perchloroethylene (PCE) in dry-cleaned garments was studied at a large semiconductor manufacturing facility. A new method was developed to measure PCE levels, which was used to detect concentrations ranging from 0.83 to 32.01ppm in the garment.
Journal of Occupational Medicine, Mar. 1987, Vol.29, No.3, p.243-244. 4 ref.

CIS 88-1246 Duncan Saunders L., Ames R.G., Knaak J.B., Jackson R.J.
Outbreak of Omite-CR-induced dermatitis among orange pickers in Tulare County, California
An outbreak of dermatitis cases among 198 orange pickers employed by a Tulare County, California, packinghouse was investigated. Dermatitis was contracted by 114 (58%) of the 198 workers exposed when Omite-CR-treated fields were harvested. The dermatitis occurred predominantly in the exposed areas of the neck and chest. A dose-response association with dermatitis was suggested for Omite-CR (Propargite) exposure, but not for Carzol, Omite-CR + Carzol, or other pesticides. Because no violations of pesticide preharvest intervals or application rates were found, it appears that residue degradation was not given adequate consideration in the registration of Omite-CR, thus compromising the safety of the worker.
Journal of Occupational Medicine, May 1987, Vol.29, No.5, p.409-413. Illus. 6 ref.

CIS 88-1366 Gan S.L., Goh C.L., Lee C.S., Hui K.H.
Occupational dermatosis among sanders in the furniture industry
The prevalence of occupational skin disease was found to be 3.8% in a study of 479 sanders in the furniture-making industry in Singapore. Seventeen species of wood imported from South-East Asia were used. The most common dermatoses from wood dust were pruritus (1.6%), irritant contact dermatitis (1.6%) and serosis (1.4%). Two sanders had miliaria. None had allergic contact dermatitis from wood dust. The arms and trunk were the most common site for pruritus and dermatitis from wood dust. It appeared that the woods commonly used in the furniture-making industry are weak sensitisers. Appropriate preventive measures against irritant dermatitis such as dust control, protective clothing, and good personal hygiene should be adequate to prevent occupational dermatitis among the sanders.
Contact Dermatitis, Oct. 1987, Vol.17, No.4, p.237-240. 6 ref.

CIS 88-1274 Srinivas C.R., Kulkarni S.B., Menon S.K., Krupashankar D.S., Iyengar M.A., Singh K.K., Sequeira R.F., Halla K.R.
Allergenic agents in contact dermatitis from Holigarna ferruginea
Nine of 10 patients who developed dermatitis following contact with Holigarna ferruginea and 5 of 35 asymptomatic volunteers showed a positive patch test reaction to 2% W/V acetone extract of the plant's resinous exudate. Six albino rats were sensitised following 3 weekly applications of the same extract. Laccol (3-heptadecadienyl catechol) was identified as the active principle in the exudate. Plants of the genus Holigarna, a source of lacquer, may be an important cause of occupational dermatitis in India.
Contact Dermatitis, Oct. 1987, Vol.17, No.4, p.219-222. Illus. 6 ref.

CIS 88-1273 Lisi P., Caraffini S., Assalve D.
Irritation and sensitization potential of pesticides
A pesticide series of 36 substances was patch tested in 652 subjects to establish the optimal test concentration and the frequency of irritant and allergic reactions. Allergic reactions to fungicides were found in 46 thiophthalimides (captan, folpet and difolatan) were the most common. Irritant and allergic reactions to other pesticides (insecticides, herbicides, etc.) were rare. Sensitivity to pesticides was significant in patients who work, or have worked, on the land. Cross sensitivity to bis-dithiocarbamates or thiophthalimides is possible.
Contact Dermatitis, Oct. 1987, Vol.17, No.4, p.212-218. 25 ref.

CIS 88-1034 MacAulay J.C.
Orchid allergy
Case report of a professional orchid grower who became sensitised to orchid pollen. Gloves, long sleeves and a mask provided effective protection. Steroids were used to treat the rash that appeared in the absence of protective equipment.
Contact Dermatitis, Aug. 1987, Vol.17, No.2, p.112-113. 11 ref.

CIS 88-915 Bedello P.G., Goitre M., Roncarolo G., Bundino S., Cane D.
Contact dermatitis to rhodium
Case report of a goldsmith who developed dermatitis of the hands as a result of rhodium plating articles of jewellery. This is the first report of rhodium sensitisation.
Contact Dermatitis, Aug. 1987, Vol.17, No.2, p.111-112. 1 ref.

CIS 88-865 Olumide Y.
Contact dermatitis in Nigeria (I). Hand dermatitis in women
Of 545 consecutive contact dermatitis clinic patients, 271 (49.7%) were women, 29 (10.7%) of whom had hand dermatitis alone. Seventeen (58.6%) of these hand cases were allergic, the main sensitisers being nickel and essential oils in oranges. Dressmakers were mostly affected by nickel, while orange sellers and peelers were positive to orange peel, fragrance mix, balsam of Peru and formaldehyde in varying combinations. Eight (27.6%) of the hand cases were due to irritants and wet jobs, and possibly to allergens not tested. Twenty-four (83%) of the hand cases were occupational. Only 1 Nigerian woman had true housewife's hand dermatitis. It was not possible to define the role of atopy because of unreliable histories. Two cases of pompholyx and a negative patch test occurred in the first trimester of pregnancy.
Contact Dermatitis, Aug. 1987, Vol.17, No.2, p.85-88. 17 ref.

CIS 88-1030 Bendsöe N., Björnberg A., Löwhagen G.B., Tengberg J.E.
Glass fibre irritation and protective creams
Five commercial products were tested pairwise as prophylaxis against itching and irritation from glass fibres: a commercial cream for glass fibre itching, a silicone spray, an emollient cream, a fatty ointment, and a "cream-ointment". The preparations were of very limited value in protection against glass fibre irritation. Some workers even experienced exacerbated itching from all the preparations, including the cream marketed for protection against glass fibre irritation. Only 25% of a group of workers with severe glass fibre itching still used an emollient cream after 12 weeks.
Contact Dermatitis, Aug. 1987, Vol.17, No.2, p.69-72. 1 ref.

CIS 88-875 Géraut C.
Occupational skin diseases
Dermatoses professionnelles [in French]
Update covering dermatoses due to biological agents (viruses, bacteria, parasites, fungi), those due to physical agents (mechanical trauma, foreign bodies that penetrate the skin, vibrations, bad climatic conditions, infrared, ultraviolet or ionising radiations), non-eczematous dermatoses due to chemical agents and eczematous dermatoses due to chemical agents, whether localised in the fingers, the hands, the arms or other parts of the body. Medical and technical prevention of these dermatoses, prevention of recurrence, compensation in France.
Encyclopédie médico-chirurgicale, Intoxications, 1987, 18p. Illus. 17 ref.

CIS 88-980 Conde-Salazar L., González M.A., Guimaranes D., Romero L.
Professional radiodermatitis
Radiodermitis profesional/Radiodermitis profesional [in Spanish]
Ten health service professionals suffering from chronic radiodermatitis were examined. They had all been working with x-rays for more than 7 years using old fashioned equipment. In all cases except one, the left hand was the most affected. The progressive character of the dermatitis was evident, and in some cases it had required amputation of fingers.
Medicina y seguridad del trabajo, Jan.-Mar. 1987, Vol.34, No.134, p.26-29. 7 ref.

CIS 88-924 Storetvedt Heldaas S., Andersen A.A., Langård S.
Incidence of cancer among vinyl chloride and polyvinyl chloride workers: Further evidence for an association with malignant melanoma
This is a follow-up study. The results supported the previous conclusions concerning excess malignancies due to vinyl chloride.
British Journal of Industrial Medicine, Apr. 1987, Vol.44, No.4, p.278-280. 15 ref.

CIS 88-580 Foussereau J.
Irritant dermatitis due to glass fibre and rock wool
Les dermites par irritation aux fibres de verre, à la laine de verre et à la laine de roche [in French]
Information note for occupational physicians. Topics: occupations at risk (production of glass fibre, insulation work in the electronics and construction industries); clinical studies; aetiology and pathology of irritation; diagnosis (the allergens include epoxy resins, formaldehyde-paratertiarybutylphenol resins, quaternary amines, lubricants, formaldehyde, dibutyl phthalate and acrylic resins); technical prevention (collective and personal); medical prevention; compensation.
Documents pour le médecin du travail, 1st Quarter 1987, No.29, p.13-16. Illus. 32 ref.

CIS 88-664 Srinivas C.R., Balachandran C., Singh K.K.
Occupational dermatosis and allergic contact dermatitis in a toddy tapper
The occupation of toddy tappers is to recover sap from coconut trees. This involves climbing the trees. Although various skin disorders ar common among these workers, the case reported in this note is the first recorded instance of allergic reactions to coconut bark and leaf sheath.
Contact Dermatitis, May 1987, Vol.16, No.5, p.294-295. Illus. 2 ref.

CIS 88-547 Pryce D.W.
Allergic contact dermatitis from 2-chlorobenzoyl chloride azine
The title compound is an intermediate in the manufacture of a new acaricide. Within 2 months of exposure to the intermediate, 10 production operators (25% of the operators) and 2 maintenance engineers developed dermatitis. Process modifications were made to reduce exposure.
Contact Dermatitis, May 1987, Vol.16, No.5, p.285-286. 5 ref.

CIS 88-665 Cole G.W.
Mycobacterium marinum infection in a mechanic
M. marinum is a common cause of occupational mycobacterial skin disease. However, it has previously been seen only in persons having contact with water in nature or in aquariums. The present case involved a mechanic who reconditioned water pumps. The infection was cured by antibiotics.
Contact Dermatitis, May 1987, Vol.16, No.5, p.283-284. 3 ref.

CIS 88-537 Valsecchi R., Cassina P., Cainelli T.
Contact toxic epidermal necrolysis
Toxic epidermal necrolysis is a life-threatening disorder in which epidermal necrolysis results in extensive shedding of the skin, producing the appearance of scalding. This note describes 2 cases of toxic epidermal necrolysis due to contact with the third intermediate in the manufacture of the antihelminthic drug tetramisole. The compound is a 1,2-disubstituted thiazole.
Contact Dermatitis, May 1987, Vol.16, No.5, p.277. 4 ref.

CIS 88-536 Pigatto P.D., Polenghi M.M., Altomare G.F.
Occupational dermatitis in bakers: a clue for atopic contact dermatitis
6 patients are described who developed contact dermatitis after cereal contact on atopic skin for periods of 2-20 years. 2 patients were wheat-flour patch-test-positive. They had punch biopsies taken: sections showed features of contact dermatitis. There were many dendrite cells located perivascularly in the papilla and in the epidermidis, intensely positive for monoclonal anti-IgE antibody. In control atopic subjects, there were a few perivascular IgE-positive cells, probably mastocyes. This study shows that there may be a relationship between some allergens and atopic eczema in patients exposed to them in the course of their work. In some cases, there was a true allergic contact dermatitis.
Contact Dermatitis, May 1987, Vol.16, No.5, p.263-271. Illus. 14 ref.

CIS 88-535 Conde Salazar L., González M. A., Guimaraens D., Romero L.V.
Dermatosis due to thioureas
Dermatosis por tioureas/Dermatosis por tioureas [in Spanish]
Review of the different uses of thioureas in industry (manufacture of shoes, rubber clothes, photocopy paper etc.) and of the cutaneous affections observed among both workers and users of the final products. Allergic contact dermatitis due to thiourea has been found among persons using these products. In Spain, only 3 cases of sensibilisation have been reported. In the first case it was due to swimming goggles and in the second to sport shoes. The third case was a construction worker who could have been affected by the use of rubber gloves or shoes.
Medicina y seguridad del trabajo, Apr.-June 1987, Vol.34, No.135, p.17-20. 14 ref.

CIS 88-319 Tosti A., Melino M., Veronesi S.
Contact urticaria to tobacco
Report of a patient whose urticaria appeared after 11 years of exposure to tobacco in a cigar and cigarette factory. None of the 750 other workers in the factory suffered from urticaria. Tobacco is well known as an irritant; it should be added to the list of agents that produce contact urticaria by an immunological mechanism.
Contact Dermatitis, Apr. 1987, Vol.16, No.4, p.225-226. 5 ref.

CIS 88-244 Fisher A.A.
Contact urticaria and anaphylactoid reaction due to corn starch surgical glove powder
Although contact urticaria due to cornstarch was first reported in the literature in 1986, personal communications among physicians and other health care personnel suggest that the problem is not a rare one. There is at least one brand of surgical glove on the world market that does not contain cornstarch powder.
Contact Dermatitis, Apr. 1987, Vol.16, No.4, p.224-225. 5 ref.

CIS 88-318 Dannaker C.J., White I.R.
Cutaneous allergy to mustard in a salad maker
A case of allergic contact dermatitis to mustard (Brassica nigra) in a salad maker is reported. The sources of skin contact included a commercial salad cream, a vinaigrette, and various members of the mustard family, Cruciferae. The Cruciferae include many salad vegetables and condiments which contain allergenic isothiocyanates. The extent of skin contact among salad makers and other food handlers may be significant, and sensitisation to isothiocyanates from this large family of vegetables may be an important cause of food contact allergy in these individuals.
Contact Dermatitis, Apr. 1987, Vol.16, No.4, p.212-214. Illus. 7 ref.

CIS 88-248 Lockey J.D., Kelly C.R., Cannon G.W., Colby T.V., Aldrich V., Livingston G.K.
Progressive systemic sclerosis associated with exposure to trichloroethylene
Although neither the aetiology nor pathogenesis of progressive systemic sclerosis (scleroderma) has been established, this disease has been associated with a wide variety of solvents. An example is given of a 47-year old woman with previous excellent health who developed fatal progressive systemic sclerosis after a single 2.5-hour predominantly dermal exposure to trichloroethylene. During a period of 10 months the patient developed proximal scleroderma, reflux oesophagitis, microangiopathic haemolytic anaemia, restrictive pulmonary disease, pericarditis with effusion, and renal insufficiency with severe hypertension. Renal and skin biopsies were consistent with progressive systemic sclerosis.
Journal of Occupational Medicine, June 1987, Vol.29, No.6, p.493-496. Illus. 26 ref.

CIS 88-241 Jolanski R., Estlander T., Kanerva L.
Contact allergy to an epoxy reactive diluent: 1,4-butanediol diglycidyl ether
Three female workers in a brush factory developed contact allergy from a 2-component epoxy glue containing epoxy resin (37% by weight), reactive diluents, i.e. 1,4-butanediol diglycidyl ether (BDDGE) 3%, glycidyl ethers of aliphatic alcohols (Epoxide 8) 0.05% and phenyl glycidyl ether (PGE) 0.01% and inert fillers. All 3 patients were positive to the resin component of the glue and to BDDGE, indicating that BDDGE was the main allergen. Two of the patients reacted to PGE, but none to Epoxide 8. Two of the patients did not react to epoxy resin, indicating that BDDGE may be an even stronger sensitiser in humans than epoxy resin, and that it does not cross-react with epoxy resins. Permeation studies revealed that BDDGE penetrates disposable PVC and rubber gloves in less than 30min. Thus, contaminated gloves should be replaced immediately. Reactive diluents should be included in patch test series if contact allergy to epoxy products is suspected.
Contact Dermatitis, Feb. 1987, Vol.16, No.2, p.87-92. 19 ref.

CIS 88-317 Gonçalo S.
Contact sensitivity to lichens and compositae in Frullania dermatitis
Forty-eight patients with allergic contact dermatitis from Frullania were patch tested with a lichen mix, compositae (flowering plants) and lichen acids. Twenty-seven were senstitive to Frullania and lichens. Parmelia caperata and Parmelia reticulata were positive in all, and in a descending order of positivity, Pseudovernia furfuracea, Evernia prunastri, Usnea spp, Ramalina lusitanica d-Usnic and evernic acids and atranorin were the main responsible allergens.
Contact Dermatitis, Feb. 1987, Vol.16, No.2, p.84-86. 13 ref.

CIS 88-182 Andersen K.E., Benezra C., Burkows D., Camarasa J., Dooms-Goossens A., Ducombs G., Frosch P., Lachapelle J.M., Lahti A., Menné T., Rycroft R., Scheper R., White I., Wilkinson J.
Contact dermatitis - A review
In recent years, understanding of contact dermatitis has greatly increased. This paper is a review of present knowledge of the mechanisms involved in contact dermatitis and related phenomena, the investigation of these events and the emergence of significant new allergens during the last 5 years.
Contact Dermatitis, Feb. 1987, Vol.16, No.2, p.55-78. 256 ref.

CIS 88-240 Fischer T., Fregert S., Thulin I., Trulsson L.
Unhardened epoxy resin in tool handles
An electrician developed hand eczema when using certain screwdrivers, and reacted to epoxy resin in patch tests. Although the screwdriver handles were nominally made of cellulose acetate, the manufacturer reported that small amounts of epoxidised soybean oil and low-molecular-weight bisphenol A-type epoxy resin were included in the material as heat stabilisers. A survey of plastic tool handles showed that only a limited number of the cellulose acetate handles contained epoxy compounds.
Contact Dermatitis, Jan. 1987, Vol.16, No.1, p.45. 2 ref.

CIS 88-239 Handfield-Jones S., Boyle J., Harman R.R.M.
Contact allergy caused by metal sprays
Report of a case of a worker who coated pipes with synthetic rubber. He shoed no reaction to rubber or rubber chemicals in patch tests, but showed strong positive reactions to nickel and chromium. Investigation showed that he worked near 2 metal spraying areas where airborne nickel levels were 4 times higher and chromium up to 18 times higher than the UK Health and Safety Executive recommended maximum time-weighted averages. Recognised risks of metal spraying include dust, explosion and fume fever; nickel or chrome allergy has not been recognised previously.
Contact Dermatitis, Jan. 1987, Vol.16, No.1, p.44.

CIS 88-238 Fowler J.F.
Occupational dermatitis from stamp pad ink
Report of a case of eczema in a bank employee who spent long periods marking cheques and documents with rubber stamps. Patch testing showed her to be allergic to the red stamp pad ink, which contained p-phenylazoaniline. As she also reacted to p-phenylenediamine, which is an intermediate in the production of p-phenylazoaniline that might have been present in the ink, the precise chemical identity of the causative agent remains unclear. Careful avoidance of contact with the ink prevented recurrence of the problem.
Contact Dermatitis, Jan. 1987, Vol.16, No.1, p.38. 2 ref.

CIS 88-237 Aberer W.
Allergy to colophony acquired backstage
The masseur of a famous ballet company developed severe contact dermatitis of his hands. In skin tests, not one of the suspected 23 different massage creams that the members of the ballet made him use gave a positive reaction. Only colophony, which was included in the standard test series, was positive. Colophony is regularly used in the shoes of dancers on wooden stages to prevent slipping. The masseur had to change his place of employment.
Contact Dermatitis, Jan. 1987, Vol.16, No.1, p.34-36. 8 ref.

CIS 88-256 Niinimäki A.
Scratch-chamber tests in food handler dermatitis
Foods were tested by the scratch-chamber and open application techniques in 80 hand dermatitits patients, 55 of whom were food handlers. Both immediate and delayed reactions were seen. Most immediate scratch-chamber test reactions were provoked by vegetables and spices in patients with birch pollen allergy, and most delayed reactions from spices in patients with allergy to balsam of Peru, and from onion and leek. The evaluation of allergic and irritant reactions was difficult. Positive open application tests were seen in about 75% of patients with immediate or delayed scratch-chamber reactions. Immediate reactions from vegetables, fish and meat, and delayed reactions from orange and lemon peel and onion showed the best clinical relevance. Wet work, surface-active agents and other irritant factors were considered the main causes, and food allergies only as contributory factors in food handler hand dermatitis.
Contact Dermatitis, Jan. 1987, Vol.16, No.1, p.11-20. Illus. 40 ref.

CIS 88-301 Jones R.R.
Ozone depletion and cancer risk
An almost 40% reduction in ozone springtime levels since the 1970's has been noted in the air above Antarctica. The large-scale release into the asmosphere of man-made pollutants, particularly of chlorofluorocarbons (CFCs) and nitrous oxide, are thought to be implicated. This article explores ozone chemistry, and the biological consequences if the process of ozone depletion was extended over densely populated areas of the earth. The main such consequence would be a significant increase in the incidence of skin cancer (including melanoma) among people who spend much time in the sunlight, including outdoor workers. It is suggested that a serious worldwide attempt be made to reduce the release into the atmosphere of CFCs.
Lancet, 22 Aug. 1987, Vol.2, No.8556, p.443-446. Illus. 34 ref.

CIS 87-1355 Foussereau J.
Allergic dermatitis due to topically applied medications and dressing materials in occupational medicine
L'eczéma allergique aux médicaments et objets de pansement en médecine du travail [in French]
Contents of this information note: clinical symptoms of allergic dermatitis due to topically applied medications; the allergological investigation; description of the allergens in question (topical anaesthetics, quaternary ammonium compounds, mercury-based antiseptics, antibiotics, balsam of Peru, laurel oil, thyme, niaouli, geranium and rose-oil extracts, asiaticoside, corticoids); allergens responsible for reactions to adhesive tape (colophony, vulcanisation accelerators, lanolin, etc.); cross reactions; preparation of a certificate indicating the presence of allergies in a person, in which the commercial products containing the allergens in question are mentioned.
Documents pour le médecin du travail, 2nd Quarter 1987, No.30, p.99-103. Illus. 31 ref.

CIS 87-1346 Clark E.G.
Risk of isothiazolinones
Two case studies of workers accidentally exposed to concentrated biocides containing isothiazolinones used as biocides in water cooling towers or air conditioing plants. Skin irritation was the main effect of the exposure.
Journal of the Society of Occupational Medicine, Spring 1987, Vol.37, No.1, p.30-31. Illus. 4 ref.

CIS 87-994 Najaël
Occupational diseases due to exposure to selenium and its inorganic compounds
Affections professionnelles résultant de l'exposition au sélénium et à ses composés minéraux [in French]
Information note on the harmful effects of selenium compounds. Contents: physical and chemical properties of selenium and its principal compounds; uses; pathology and toxicology (irritation of the skin and mucous membranes; these irritations are compensable under French law); radioactive selenium; fire hazards; French regulations; protection.
Sécurité - sciences et techniques, Apr. 1987, No.63, p.65-72. Illus. 11 ref.

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