Alcohols - 685 entries found

Your search criteria are

• Alcohols

1993

CIS 93-1783 1,2-Butanediol
International chemical safety card. Short-term exposure effects: eye irritation. Long-term exposure effects: may affect the kidneys.
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1993. 2p.

CIS 93-1940 Macaluso M., Delzell E., Rose V., Perkins J.
Use of organic solvents and potential worker exposure in the motor vehicle manufacturing industry
This survey was designed to assist with planning epidemiological studies of the effects of solvent exposure among motor vehicle manufacturing workers. The objectives were to identify subgroups of workers with solvent exposure and to evaluate the availability of data for a job-exposure matrix (JEM). Thirty-one plants, employing a total of 97,655 hourly workers, participated in the survey. About 14% of these workers use organic solvents (direct exposure) and 19% work in the proximity of solvent-using operations (indirect exposure). However, only 3% have direct exposure, and 6% indirect exposure to large-volume (≥100 gallons/month)/high-frequency (hourly) use solvents. The highest solvent exposure prevalence occurred in plants manufacturing engines and power train components and in metal degreasing/cleaning and painting tasks, and entailed exposure to petroleum fractions, aromatic hydrocarbons, alcohols and ketones. A JEM can be developed using plant records on job titles, work histories, production scheduling, and plant engineering, and using the corporate computerised personnel and industrial hygiene databases. However, information on solvent use and on exposure is adequate only for recent time periods.
American Journal of Industrial Medicine, Mar. 1993, Vol.23, No.3, p.449-460. 18 ref.

CIS 93-1463 Propylene glycol
International chemical safety card. Short-term exposure effects: irritation of the eyes.
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1993. 2p.

CIS 93-1458 Isobutyl alcohol
Alcohol isobutílico [in Spanish]
Chemical safety sheet published by the Consejo Interamericano de Seguridad, 33 Park Place, Englewood, NJ 07631, USA. Health hazards: irritation of the eyes, upper respiratory tract and skin; liquid defats the skin; dermatitis.
Noticias de seguridad, July 1993, Vol.55, No.7. 4p. Insert.

CIS 93-1648 Hansen L.E.
Commission of the European Communities
Occupational exposure limits. Criteria document for phenol
Review of the available literature on the toxicology of phenol. Few data are available on human exposure; most reports are case histories from accidents, mostly with dermal exposure and from medical use of phenol. The substance is readily absorbed (possible in lethal amounts) through the skin, both as vapour and from aqueous solutions. It is corrosive to the skin and eyes, and inhalation causes irritation of the respiratory tract. The primary effects of acute accidental exposure are on the liver and kidney. Long-term occupational exposure may lead to an increased risk of ischaemic heart disease.
Office for Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg, 1993. v, 59p. ca.170 ref. Price: ECU 7.50.

CIS 93-1274 Bas Bueno de Mesquita H., Doornbos G., van der Kuip D.A.M., Kogevinas M., Winkelmann R.
Occupational exposure to phenoxy herbicides and chlorophenols and cancer mortality in the Netherlands
A cohort of 2,310 workers from two plants who manufacture and prepare chlorophenoxy herbicides in the Netherlands was followed during the periods 1955-1985 and 1965-1986, respectively. In 1963, there was an industrial accident in one factory with concomitant release of dioxin into the environment. Mortality data on 963 exposed and 1,111 nonexposed men were evaluated by external and internal comparison. Compared with national rates, total mortality (94 deaths, SMR = 101; 95% confidence interval [CI], 82-124) and cancer mortality (31 deaths, SMR = 107; 95% CI, 73-152) for exposed workers were not significantly increased. A statistically insignificant increase was observed for non-Hodgkin's lymphoma. There was no increase in either total mortality in cancer mortality among the 139 workers probably exposed to dioxins during the 2,4,5-trichlorophenol production accident. Compared with nonexposed workers, exposed workers did not exhibit a higher total mortality. Mortality due to all cancers and respiratory cancer was not significantly elevated. These findings suggest that the increases in cancer mortality among workers exposed to phenoxy herbicides and chlorophenols may be attributable to chance.
American Journal of Industrial Medicine, Feb. 1993, Vol.23, No.2, p.289-300. 20 ref.

1992

CIS 02-1094 1-Propanol
1-Propanol [in French]
Chemical safety information sheet. Synonyms: n-propanol; n-propyl alcohol; propyl alcohol. Acute toxicity: irritation of the digestive tract and digestive disorders (ingestion); irritation of the skin and eyes; splashes may induce conjunctivitis and corneal ulcerations. Chronic toxicity: contact dermatitis. Exposure limits (France): TWA = 500mg/m³ (200ppm). EEC number and mandatory labelling codes: No.603-003-00-0; F, R11, S7, S16. Complete datasheet collection on CD-ROM analysed under CIS 02-1407.
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, CD-ROM CD 613, 2002. 4p. Illus. 23 ref.

CIS 02-1069 2-Propanol
2-Propanol [in French]
Chemical safety information sheet. Synonym: isopropyl alcohol. Acute toxicity: eye irritation; digestive disorders, symptoms similar to alcohol intake which may lead to coma, hypothermia, respiratory depression, hypotension (ingestion). Chronic toxicity: carcinogen (paranasal and laryngeal cancer); skin irritation and sensitization. Exposure limits (France): ceiling value = 980mg/m³ (400ppm). EEC number and mandatory labelling codes: No.603-003-00-0; F, R11, S7, S16. The complete datasheet collection on CD-ROM has been analysed under CIS 01-201.
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, CD-ROM CD 613, May 2000. 5p. Illus. 25 ref.

CIS 02-47 Benzyl alcohol
Alcool benzylique [in French]
Chemical safety information sheet. Update of data sheet already summarized in CIS 91-33. Synonyms: phenylmethanol; α-hydroxytoluene. Acute toxicity: digestive signs; central nervous system damage; irritation of the eyes, skin and mucous membranes. Chronic toxicity: headache; vertigo; gastrointestinal disorders; irritation skin diseases. EEC number and mandatory labelling codes: No.603-057-00-5; Xn, R20/22, S26. Complete datasheet collection on CD-ROM analysed under CIS 01-201.
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, Rev.ed., CD-ROM CD 613, 2000. 4p. Illus. 15 ref.

CIS 02-40 Hydroquinone
Hydroquinone [in French]
Chemical safety information sheet. Update of data sheet already summarized in CIS 89-1470. Synonyms: 1,4-benzenediol; p-dihydroxybenzene. Acute toxicity: digestive disorders due to the caustic effect; systemic damage with neuromuscular disorders; methaemoglobinaemia sometimes giving rise to haemolysis with jaundice, oliguria and anuria; caustic skin and eyes lesions. Chronic toxicity: ocular effects (irritation, photophobia; brown-greenish colouring of the conjunctive membranes and cornea, changes in the cornea thickness and curvature, astigmatism, diminution visual acuity) whose severity is correlated to exposure; irritative skin diseases or allergic reactions which may induce sensitization; depigmentation of the skin; dyspnoea and bronchoconstriction. Exposure limits (France): TWA = 2mg/m³. EEC number and mandatory labelling codes: No.604-005-00-4; Xn, R20/22, S2, S24/25, S39. Complete datasheet collection on CD-ROM analysed under CIS 01-201.
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, Rev.ed., CD-ROM CD 613, 2000. 4p. Illus. 21 ref.

CIS 01-1609 2-Propene-1-ol
2-Propène-1-ol [in French]
Chemical safety information sheet. Update of data sheet already summarized in CIS 91-63. Acute toxicity: irritation of the nasal and ocular mucous membranes; skin contact may cause irritation and sometimes burns; systemic symptoms. Chronic toxicity: no disorders following extended exposure have been reported. Exposure limits (France): TWA = 5mg/m³ (2ppm); ceiling value = 10mg/m³ (4ppm). EEC number and mandatory labelling codes: No.603-015-00-6; T, R10, R23/24/25, R36/37/38, S36/37/39, S38, S44. Complete datasheet collection on CD-ROM analysed under CIS 01-201.
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, Rev.ed., CD-ROM CD 613, 2000. 4p. Illus. 18 ref.

CIS 01-992 Cresols
Crésols [in French]
Chemical safety information sheet. Update of data sheet already summarized in CIS 89-1461. Acute toxicity: digestive disorders due to the caustic effect; systemic disorders (neuromuscular and cardiovascular disorders, methaemoglobinaemia); hepatic cytolyis; renal tubular necrosis; pulmonary oedema which may be delayed; chemical burns. Chronic toxicity: functional disorders due to systemic poisoning; hepatic, renal and pancreatic damage; skin diseases which may cause necrosis. Exposure limit (France): TWA = 22mg/m³ (5ppm). EEC number and mandatory labelling codes: No.604-004-00-9; T, R24/25, R34, S36/37/39, S44 (isomer mix). Complete datasheet collection on CD-ROM analysed under CIS 01-201.
Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, Rev.ed., CD-ROM CD 613, May 2000. 4p. Illus. 24 ref.

CIS 96-946 Maroni M.
Threshold limit values for chemicals in the workplace
Valori limite di esposizione ad agenti chimici negli ambienti di lavoro [in Italian]
Data sheets and toxicological profiles are presented for benzene, pentachlorophenol, arsenic, vanadium, tetraethyllead, tetramethyllead, xylene, toluene and cadmium. The information includes teratogenicity, mutagenicity, carcinogenic effects and threshold limit values (including those for the US and Italy) taken from the reviewed literature.
Prevenzione oggi, July-Sep. 1992, Vol.4, No.3, p.39-73. 69 ref.

CIS 94-1994 Iwasa T., Abe T., Hiramatsu K., Kubori S., Inoue N., Fujishiro K., Koga M.
Fulminant hepatitis after the inhalation of dichloropropanols
Jikuroropropanoru bakuro go ni okotta gekishō kan'en no ichi rei [in Japanese]
A 59-year-old worker in a chemical plant developed general malaise, nausea and vomiting several hours after cleaning a tank that had contained dichloropropanols. He had no previous history of liver trouble. When the victim was admitted to the hospital, his liver was swollen and the results of blood analysis showed several abnormalities. In spite of therapy, the patient died on the fifth day after the accident. Because 1,3-dichloro-2-propanol and 2,3-dichloro-1-propanol were detected in the blood samples taken at the time of admission, the fatal fulminant hepatitis was attributed to exposure to these compounds. This seems to be the first report of such a case.
Journal of UEOH, 1 Mar. 1992, Vol.14, No.1, p.67-71. Illus. 2 ref.

CIS 94-312 Franzblau A., Levine S.P., Schreck R.M., D'Arcy J.B., Qu Q.S.
Use of urinary formic acid as a biologic exposure index of methanol exposure
Interest has developed in the use of urinary formic acid as a biological exposure index of occupational methanol exposure. Four human subjects were exposed to approximately 200ppm of methanol in a test chamber for six hours. Ambient air in the chamber was monitored for methanol, while urine was monitored for formic acid. Urine specimens were collected immediately before, immediately after, and 16h following cessation of exposure to methanol. Mean urinary formic acid was increased from baseline at the end of the exposure session (though not significantly), but had returned to baseline in samples collected 16h following cessation of exposure. These results suggest that measurement of urinary formic acid in specimens collected 16h following cessation of exposure to methanol may not be an appropriate approach to biologically assess methanol exposure.
Applied Occupational and Environmental Hygiene, July 1992, Vol.7, No.7, p.467-471. 33 ref.

CIS 94-246 Stewart P.A., Herrick R.F., Feigley C.E., Utterback D.F., Hornung R., Mahar H., Hayes R., Douthit D.E., Blair A.
Study design for assessing exposures of embalmers for a case-control study - Part I. Monitoring results
To quantify exposure levels for a study of embalmers, a series of embalmings was performed using an experimental design to determine the effect of certain work parameters on the concentration of airborne contaminants. Personal exposures and area concentrations of formaldehyde, methanol, phenol, and particulates were measured during 25 embalmings while controlling the level of ventilation, the concentration of embalming solution, and the type of case (autopsy or intact body). In addition, bischloromethyl ether (BCME) and selected microorganisms were measured during a few embalmings. Personal formaldehyde exposures ranged from 0.31 to 8.72ppm for full-period exposures (51-121min). Methanol levels ranged from 0.54 to 21.83 ppm. Particulate mass concentrations were low, and measurable phenol levels were observed in only 40% of procedures. Airborne microorganisms were also found to be at low levels and no BCME was detected. Ventilation played the most important role out of the three controlled variables.
Applied Occupational and Environmental Hygiene, Aug. 1992, Vol.7, No.8, p.532-540. Illus. 35 ref.

CIS 94-109 Phenol
Phénol [in French]
International chemical safety card. Short term exposure effects: skin absorption; corrosive to the eyes, the skin and the respiratory tract; pulmonary oedema (delayed effects); central nervous system, liver and kidney disorders. Long term exposure effects: dermatitis; kidney and liver damage.
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1992. 2p. Illus.

CIS 94-108 Pentachlorophenol
Pentachlorophénol [in French]
International chemical safety card. Short term exposure effects: skin absorption; delayed effects; irritation of skin and eyes; corrosive to the respiratory tract; pulmonary oedema; heart failure. Long term exposure effects: dermatitis; disorders of the central nervous system, lungs, liver and kidneys.
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1992. 2p. Illus.

CIS 94-96 Methanol
Méthanol [in French]
International chemical safety card. Danger symbols: highly flammable; toxic. Short-term exposure effects: delayed effects; skin absorption; corrodes the eyes, skin and respiratory tract; neurotoxic effects (central nervous system); blindness. Long-term exposure effects: dermatitis; neurotoxic effects; vision disorders. EC identification number and labelling codes: 603-001-00-X; F; T; R11-23/25; S2-7-16-24. United Nations number and hazard class: UN 1230 (3; 6.1; II).
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1992. 2p. Illus.

CIS 94-83 Ethanol (anhydrous)
Ethanol (anhydre) [in French]
International chemical safety card. Danger symbols: highly flammable. Short term exposure effects: irritation of skin, eyes and respiratory tract; neurotoxic effects. Long term exposure effects: hepatic damage; neurotoxic effects (central nervous system). EC identification number and labelling codes: 603-002-00-5; F; R11; S7-16. United Nations number and hazard class: UN 1170 (3-102 & 144).
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1992. 2p. Illus.

CIS 94-70 p-Cresol
p-Crésol [in French]
International chemical safety card. Danger symbol: toxic. Short-term exposure effects: skin absorption; delayed effects; corrosive to skin and mucous membranes; pulmonary oedema; neurotoxic effects (central nervous system). Long-term exposure effects: dermatitis; lung disorders; renal and hepatic damage. EC identification number and labelling codes: No.604-004-00-9; T; R24/25-34; S2-28-44. United Nations number and hazard class: UN 2076 (6.1; II).
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1992. 2p. Illus.

CIS 94-69 o-Cresol
o-Crésol [in French]
International chemical safety card. Danger symbol: toxic. Short-term exposure effects: skin absorption; delayed effects; corrosive to skin and mucous membranes; pulmonary oedema; neurotoxic effects (central nervous system). Long-term exposure effects: dermatitis; lung disorders; renal and hepatic damage. EC identification number and labelling codes: No.604-004-00-9; T; R24/25-34; S2-28-44. United Nations number and hazard class: UN 2076 (6.1; II).
Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg; International Programme on Chemical Safety (IPCS), World Health Organization, 1211 Genève 27, Switzerland, 1992. 2p. Illus.

CIS 93-2007 Lundberg P.
Scientific basis for Swedish occupational standards - XIII
Vetenskapligt underlag för hygienska gränsvärden. 13 [in Swedish]
Consensus reports of the Criteria Group of the Swedish National Institute of Occupational Health on diethanolamine, ethanolamine, catechol, resorcinol, acetamide, dimethyl sulfoxide, ethyl chloride, dioxane, chloromethane, methylhydrazine, hydrazine, cadmium and pyridine. An appendix lists consensus reports appearing in previous volumes of Arbete och Hälsa.
Arbetsmiljöinstitutet, Förlagstjänst, 171 84 Solna, Sweden, 1992. 85p. (Eng.); 152p. (Swe.). 496 ref.

CIS 93-1115 o-sec-Butylphenol
Chemical safety information sheet taken from the newly revised edition of the NIOSH publication "Occupational Safety and Health Guidelines for Chemical Hazards". Effects of short-term exposure: irritation of the eyes, skin and respiratory tract; chemical burns.
US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, 1992. 6p. 16 ref.

CIS 93-1112 tert-Butyl alcohol
Chemical safety information sheet taken from the newly revised edition of the NIOSH publication "Occupational Safety and Health Guidelines for Chemical Hazards". Effects of short-term exposure: irritation of the eyes, nose, throat and skin; narcotic effects. Effects of long-term exposure: defatting of the skin; dermatitis.
US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, 1992. 7p. 23 ref.

CIS 93-1111 sec-Butyl alcohol
Chemical safety information sheet taken from the newly revised edition of the NIOSH publication "Occupational Safety and Health Guidelines for Chemical Hazards". Effects of short-term exposure: irritation of the eyes, nose and throat; defatting of the skin; narcotic effects. Effects of long-term exposure: dermatitis; skin sensitisation.
US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, 1992. 7p. 20 ref.

CIS 93-762 n-Butyl alcohol
Chemical safety information sheet taken from the newly revised edition of the NIOSH publication "Occupational Safety and Health Guidelines for Chemical Hazards". Effects of short-term exposure: skin absorption; irritation of the eyes, skin and upper respiratory tract; narcotic effects. Effects of long-term exposure: light sensitivity; corneal damage; defatting of the skin; eczema; may increase extent of hearing loss among workers exposed to both noise and n-butyl alcohol.
US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health (NIOSH), Division of Standards Development and Technology Transfer, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, 1992. 7p. 13 ref.

CIS 93-740 Allyl alcohol
Chemical safety information sheet taken from the newly revised edition of the NIOSH publication "Occupational Safety and Health Guidelines for Chemical Hazards". Effects of short-term exposure: skin absorption; irritation of eyes, nose, upper respiratory tract and skin; pulmonary oedema; skin burns and corrosion; muscle pain; transient corneal injuries, blurred vision and light sensitivity; poisoning. Effects of long-term exposure: may exacerbate chronic respiratory, liver and kidney disease.
US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, 1992. 7p. 14 ref.

CIS 93-911 Kintz P., Tracqui A., Mangin P.
Accidental death caused by the absorption of 2,4-dichlorophenol through the skin
A fatality resulting from skin absorption of 2,4-dichlorophenol is presented. A 33 year-old male disposing of industrial waste was splattered over portions of his right thigh and right arm with a pure solution of the chemical. Less than 10% of his body surface was contaminated. Within 20 minutes he experienced a seizure and collapsed. The compound was quantified using gas chromatography and confirmation was obtained with mass spectrometry. Blood concentration was 24.3mg/L. Other drugs, including ethanol, were not detected.
Archives of Toxicology, Apr. 1992, Vol.66, No.4, p.298-299. 7 ref.

CIS 93-577 Lee E.W., Terzo T.S., D'Arcy J.B., Gross K.B., Schreck R.M.
Lack of blood formate accumulation in humans following exposure to methanol vapor at the current permissible exposure limit of 200ppm
Accumulation of formate, the putative toxic metabolite of methanol, in the blood and the relationship between pulmonary intake and blood methanol concentration were investigated in 6 volunteers following 6hr exposures (at rest and under light exercise) to 200ppm methanol (the current OSHA 8hr-TWA permissible exposure limit). At the end of the exposures the blood methanol concentrations increased from a mean of 1.8µg/mL to 7.0µg/mL (at rest) and 8.1µg/mL (under light exercise, no statistically significant increase, even though the total amount of methanol inhaled was 1.8 times that inhaled at rest). Formate did not accumulate in the blood above the background level in any of the experiments. In conclusion, when exposure to methanol is at the < 200ppm level, (1) the biological load of methanol does not increase with light physical exercise, and (2) there is no accumulation of formate in the blood.
American Industrial Hygiene Association Journal, Feb. 1992, Vol.53, No.2, p.99-104. 18 ref.

CIS 93-507 Castelain P.Y., Com J., Castelain M.
Occupational dermatitis in the aircraft industry: 35 years of progress
A comparison of the occupational dermatitis occurring in the same aircraft factory during two separate decades, 1955-1965 and 1981-1990, is presented. Subungual pulpitis is highly specific to this industry, because of the handling of resins and sealing agents. The number of cases dropped from 122 to 40, in accordance with progress in preventive medicine and technological changes in the factory. Irritant contact dermatitis nevertheless remained appreciable, while allergic contact dermatitis greatly decreased.
Contact Dermatitis, Nov. 1992, Vol.27, No.5, p.311-316. Illus. 11 ref.

CIS 93-584 Burden A.D., Stapleton M., Beck M.H.
Dithranol allergy: fact or fiction?
A case of a psoriatic patient allergic to dithranol and coal tar is described. It is suggested that dithranol 0.001% pet. is a suitable concentration to test for dithranol allergy, as higher concentrations may produce irritant reactions. The literature on dithranol allergy is reviewed and the frequent simultaneous reactions to dithranol and coal tar discussed.
Contact Dermatitis, Nov. 1992, Vol.27, No.5, p.291-293. 13 ref.

CIS 93-229 Cicolella A.
Glycol ethers - State of the art and research prospects
Les éthers de glycol - Etat actuel des connaissances - Perspective de recherche [in French]
Glycol ethers are a family of products, the use of which, as solvents, has increased sharply during the last few years: paints, inks, varnishes, cosmetics, cleaning products, etc. Two million people are thought to be exposed at work and many more at home. Experimental data are consistent as far as testicular and developmental effects are concerned, but rather scarce for the haematological ones and non-existent for carcinogenicity. No chronic toxicity study has been published. Human data are scarce: a few cases of malformations and haematological effects as well as some epidemiological studies on morbidity (with poor exposure evaluation), and no mortality or case-control studies. The INRS has therefore launched a research programme consisting of epidemiological, clinical, toxicological and monitoring studies on exposure to glycol ethers.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 3rd Quarter 1992, No.148, Note No.1890-148-92, p.359-378. Illus. 132 ref.

CIS 92-1956 Izquierdo D.J., Sanz-Gallén D.P., Gaynés D.E., Alpuente D.L., Nogué D.S.
The principal substances used in the work environment that can produce an "Antabuse" effect
Principales sustancias utilizadas en el medio laboral que pueden producir efecto antabús [in Spanish]
The ingestion of alcoholic drinks and the simultaneous ingestion of certain mushrooms, medical drugs and/or exposure to certain chemicals can produce a number of symptoms grouped together under the name Antabuse ® effect. This article lists the principal drugs and chemical substances known to produce this effect. Particular attention is paid to disulfiram, a substance widely used for the treatment of chronic alcoholism, but also used in agriculture as a fungicide and seed desinfectant and in the manufacturing of rubber. Other important substances concerned are dimethylformamide (an organic solvent, used in particular as a solvent for polyacrylonitrile), cyanamide and calcium cyanamide (used as fertilisers and in the synthesis of thiourea and sodium cyanamide), thrichloroethylene (used, among others, as a degreaser, an insecticide and in dry-cleaning establishments), carbon tetrachloride (a highly toxic solvent) and various oximes (anti-oxidants). For each substance, the symptoms of synergic exposure to alcohol are discussed, as are the appropriate treatment methods.
Prevención, Apr.-June 1992, No.120, p.22-26. Illus. 15 ref.

CIS 92-1626 Franzblau A., Levine S.P., Burgess L.A., Qu Q.S., Schreck R.M., D'Arcy J.B.
The use of a transportable Fourier transform infrared (FTIR) spectrometer for the direct measurement of solvents in breath and ambient air - I. Methanol
A transportable Fourier transform infrared (FTIR) spectrometer has been tested for analysis of methanol vapour in alveolar and ambient air. The instrument has been found to be accurate and precise for both uses. The regions of the infrared spectrum of alveolar air samples which were used for methanol and CO₂ quantification are in the vicinity of 950-1,100cm^-1 and 2,000-2,100cm^-1, respectively. The results of a standard addition experiment show a correlation coefficient of 0.97-0.99 for methanol in alveolar or ambient air at the 30-200ppm concentration level. For CO₂ analysis in 23 alveolar air samples at the 6.1-7.6% concentration level, the mean difference in results between a non-dispersive infrared (NDIR) spectrometer and the FTIR was -0.092% with a standard deviation of 0.273% (p>0.1). Methanol concentrations in alveolar air paralleled simultaneous measurements of methanol concentration in blood. Overall, these preliminary results suggest that FTIR spectroscopy is a practical and efficient approach for simultaneous biological and area monitoring of human exposure to organic solvents.
American Industrial Hygiene Association Journal, Apr. 1992, Vol.53, No.4, p.221-227. Illus. 30 ref.

CIS 92-1108 Cresol (all isomers)
Cresol, todos los isómeros [in Spanish]
Chemical safety information sheet published by the Consejo Interamericano de Seguridad, 33 Park Place, Englewood, NJ 07631, USA. Toxicity: skin absorption; irritation of skin and eyes; neurotoxic effects; respiratory failure; pulmonary oedema; damage to liver, lung and pancreas; dermatitis.
Noticias de seguridad, Mar. 1992, Vol.53, No.3. 5p. Insert.

CIS 92-1225 Downie A., Khattab T.M., Malik M.I.A., Samara I.N.
A case of percutaneous industrial methanol toxicity
A case is presented of a consultant supervising tank cleaning prior to methanol loading at a petrochemical complex in Saudi Arabia. The consultant, wearing positive pressure breathing apparatus but no protective clothing, worked for 2-3h in the confined space of the tank and then on deck where his methanol-soaked clothing eventually dried out. Visual symptoms of acute methanol toxicity presented some 8h after exposure. The individual recovered completely following suitable treatment (administration of ethanol) in hospital.
Occupational Medicine, Feb. 1992, Vol.42, No.1, p.47-49. 18 ref.

1991

CIS 00-946 2-Bromo-2-nitro-1,3-propanediol
2-Bromo-2-nitro-1,3-propanodiol [in Spanish]
Spanish version of IPCS ICSC 0415. International Chemical Safety Card. Exposure routes: inhalation, skin absorption and ingestion. Short-term exposure effects: irritation of the skin, the eyes and the respiratory tract. Long-term exposure effects: prolonged or repeated contact may induce skin sensitization.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p. Illus.

CIS 98-1576 Hydroquinone
Hidroquinona [in Spanish]
Spanish version of IPCS ICSC 0116. International Chemical Safety Card. Topics: hydroquinone; chemical hazards; data sheet; dermatitis; elimination of spills; environmental pollution; explosion hazards; eye irritation; fire fighting; fire hazards; first aid; functional respiratory disorders; genetic effects; health hazards; IPCS; irritants; labelling; physical hazards; sensitization; Spain; storage; threshold limit values; translation; waste disposal.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 98-1132 Phenol
Fenol [in Spanish]
Spanish version of IPCS ICSC 0070 (CIS 91-1451). International Chemical Safety Card. Topics: blindness; cardiological effects; caustic substances; central nervous system; chemical burns; chemical hazards; coma; convulsions; data sheet; delayed effects; dermatitis; elimination of spills; environmental pollution; explosion hazards; fire fighting; fire hazards; first aid; health hazards; hepatic damage; IPCS; labelling; neurotoxic effects; phenol; pulmonary oedema; renal damage; respiratory insufficiency; skin absorption; Spain; storage; threshold limit values; translation; waste disposal.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 98-1127 Ethanediol
Etano-1,2-diol [in Spanish]
Spanish version of IPCS ICSC 0270 (CIS 92-1792). International Chemical Safety Card. Topics: brain tissue damage; central nervous system; chemical hazards; data sheet; elimination of spills; ethylene glycol; fire fighting; fire hazards; first aid; health hazards; IPCS; irritation; labelling; neurotoxic effects; renal damage; skin absorption; Spain; storage; threshold limit values; translation; unconsciousness; waste disposal.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 98-67 Allyl alcohol
Alcohol alílico [in Spanish]
Spanish version of IPCS ICSC 2-0095. International Chemical Safety Card. Topics: allyl alcohol; chemical burns; chemical hazards; data sheet; delayed effects; elimination of spills; environmental pollution; explosion hazards; fire fighting; fire hazards; first aid; health hazards; hepatic damage; IPCS; irritation; labelling; lacrimating agents; muscular diseases; renal damage; skin absorption; Spain; storage; threshold limit values; translation; waste disposal.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 97-1469 2,3,6-Trichlorophenol
2,3,6-Triclorofenol [in Spanish]
Spanish version of IPCS ICSC 8-0590. International Chemical Safety Card. Short-term exposure effects: skin absorption; irritation of the eyes, skin and respiratory tract; no data are available on this isomer, but a mixture of trichlorophenols may cause toxic effects on the central nervous system. Long-term exposure effects: dermatitis; a related substance, 2,4,6-trichlorophenol, is possibly carcinogenic in humans.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 97-1468 2,3,5-Trichlorophenol
2,3,5-Triclorofenol [in Spanish]
Spanish version of IPCS ICSC 8-0589. International Chemical Safety Card. Short-term exposure effects: skin absorption; no data are available on this isomer, but a mixture of trichlorophenols may cause irritation of the eyes, skin and respiratory tract and acute toxic effects on the central nervous system. Long-term exposure effects: dermatitis; a related substance, 2,4,6-trichlorophenol, is possibly carcinogenic in humans.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 97-1467 2,3,4-Trichlorophenol
2,3,4-Triclorofenol [in Spanish]
Spanish version of IPCS ICSC 8-0588. International Chemical Safety Card. Short term exposure effects: skin absorption; irritation of the eyes, skin and respiratory tract. Data on the health effects of this substance are insufficient.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 96-2030 2-Hexanol
Hexan-2-ol [in Spanish]
Spanish version of IPCS ICSC 7-0488. International chemical safety card. Short-term exposure effects: skin absorption; irritation of the eyes, skin and respiratory tract; neurotoxic effects (central nervous system). Long-term exposure effects: neurotoxic effects; liquid defats skin.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 96-2029 1,6-Hexanediol
Hexano-1,6-diol [in Spanish]
Spanish version of IPCS ICSC 7-0491. International chemical safety card. Short-term exposure effects: irritation of the eyes and respiratory tract; unconsciousness. Data are insufficiently available on the health hazards of this substance.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 96-2012 2-Phenylethanol
2-Fenil etanol [in Spanish]
Spanish version of IPCS ICSC 10-0936. International chemical safety card. Short-term exposure effects: irritation of the eyes and respiratory tract. Long-term exposure effects: neurotoxic effects (central nervous system); damage to the reproductive system.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 96-2008 2-Ethylhexanol
2-Etilhexan-1-ol [in Spanish]
Spanish version of IPCS ICSC 10-0890. International chemical safety card. Short-term exposure effects: skin absorption; irritation of the eyes and skin.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 96-471 m-Cresol
m-Cresol [in Spanish]
Spanish version of future IPCS ICSC 0646. International chemical safety card. Short-term exposure effects: skin absorption; delayed effects; irritation of the eyes, skin and respiratory tract; chemical burns; loss of consciousness. Long-term exposure effects: dermatitis; may affect the lungs, liver and kidneys; neurotoxic effects (central nervous system).
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

CIS 96-468 3-Chlorophenol
3-Clorofenol [in Spanish]
Spanish version of future IPCS ICSC 0150. International chemical safety card. Short-term exposure effects: irritation of the eyes, skin and respiratory tract.
Instituto Nacional de Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna 73, 28027 Madrid, Spain, 1991. 2p.

< previous | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 ...14 | next >