Diseases of the respiratory system (except for pneumoconiosis & similar) - 2,965 entries found
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- Diseases of the respiratory system (except for pneumoconiosis & similar)
Giannasi F., Thébaud-Mony A.
Occupational exposure to asbestos in Brazil
Exposiçõnes ocupacionais ao amianto no Brasil [in Portuguese]
Topics: asbestos processing industry; asbestos; asbestosis; Brazil; conditions of work; developing countries; legal aspects; limitation of exposure; lung cancer; mesothelioma; personal protective equipment; threshold limit values.
Revista CIPA, Oct. 1997, Vol.18, No.215, p.102-110. Illus. 7 ref.
Fishwick D., Bradshaw L.M., Slater T., Pearce N.
Respiratory symptoms, across-shift lung function changes and lifetime exposures of welders in New Zealand
In a study of 62 current welders and 75 nonwelders at the same sites in New Zealand, work-related cough was reported by 22.6% of current welders and 6.7% of nonwelders; the respective figures for at least one work-related symptom were 30.7% and 16.0%. The groups' preshift lung function did not differ. An acute decrease in forced expiratory volume in 1s in relation to work was more prevalent in welders than in nonwelders, and was more common among welders without local exhaust ventilation than among those with it. Topics: exhaust ventilation; local exhaust; long-term exposure; New Zealand; one-second forced expiratory volume; pulmonary function; respiratory diseases; smoking; welding and cutting; welding fumes.
Scandinavian Journal of Work, Environment and Health, Oct. 1997, Vol.23, No.5, p.351-358, 31 ref.
Hobbesland Å., Kjuus H., Thelle D.S.
Mortality from nonmalignant respiratory diseases among male workers in Norwegian ferroalloy plants
In a cohort of 14,730 men employed in 12 Norwegian ferroalloy plants, overall mortality from nonmalignant respiratory diseases was not increased, but mortality from bronchitis, emphysema and asthma combined was significantly increased among men with at least three years of ferrosilicon/silicon-metal (FeSi/Si-met) furnace work. This increased mortality may be associated with previous exposure to amorphous silica. Six men died of pneumonia while still employed in a ferromanganese/siliconmanganess plant. These deaths may be associated with manganese exposure. No corresponding deaths occurred among employees in FeSi/Si-met plants. Two deaths from pneumoconiosis were observed in the total cohort. Topics: asthma; bronchitis; ferromanganese; manganese; silica; cohort study; emphysema; ferroalloys; long-term exposure; mortality; Norway; ore reduction; pneumoconiosis; pneumonia; reduction furnaces; respiratory diseases.
Scandinavian Journal of Work, Environment and Health, Oct. 1997, Vol.23, No.5, p.342-350, 36 ref.
Wieslander G., Norbäck D., Edling C.
Airway symptoms among house painters in relation to exposure to volatile organic compounds (VOCs) - A longitudinal study
A study of 175 house painters from 1989 to 1992 showed no increase of asthma or respiratory symptoms in painters exposed only to water-based paint (WBP). Most painters had a mixed exposure to solvent-based paint (SBP) and WPB, the main source of volatile organic compounds being the limited use of SBP. WBP was perceived as less irritative than SBP, but complaints of airway irritation from WBP increased during the study period. The most pronounced increase of airway irritation in relation to both WBP and SBP was observed among painters with the highest solvent exposure. Results indicate that emissions of volatile organic compounds from SBP may contribute to the development of respiratory symptoms and airway irritation among these painters. Topics: asthma; epidemiologic study; exposure evaluation; functional respiratory disorders; irritation; organic compounds; painting; paints; respiratory diseases; solvents; subjective assessment; symptoms; volatile substances.
Annals of Occupational Hygiene, Apr. 1997, Vol.41, No.2, p.155-166. Illus. 17 ref.
Melbostad E., Wijnand E., Magnus P.
Chronic bronchitis in farmers
Important exposure factors for chronic bronchitis were full-time farming versus part-time farming, livestock production types (poultry, dairy, swine, horse, and combinations) and occupational dust exposures outside agriculture. Combinations of work exposure factors were significant and showed a 2- to 3-fold increase in risk for chronic bronchitis for farmers. In combination with smoking the risk increased up to 6-fold. Topics: age-linked differences; agricultural operations; airborne dust; chronic bronchitis; cross-sectional study; length of exposure; livestock rearing; obstructive ventilatory impairment; risk factors; smoking; ventilatory capacity.
Scandinavian Journal of Work, Environment and Health, Aug. 1997, Vol.23, No.4, p.271-280. 33 ref.
Wichmann H.E., Brüske-Hohlfeld I., Möhner M., Kreienbrock L., Kreuzer M., Jöckel K.H., Ahrens W., Pohlabeln H.
Lung cancer risk due to occupational exposures
Lungenkrebsrisiko durch berufliche Exposition [in German]
Topics: epidemiologic study; Germany; harmful substances; industries; job-exposure relation; lung cancer; neoplasms; occurrence; risk factors; statistical aspects.
GSF-Forschungszentrum für Umwelt und Gesundheit, Institut für Epidemiologie, Neuherberg, Germany, Aug. 1997. 642p. Illus. Bibl.ref.
Otten H., Schröder C., Willmann G.
Activities and research projects by the German Berufsgenossenschaften on the Wismut project - Current and expected findings
Berufsgenossenschaftliche Aktivitäten und Forschungsvorhaben zum Thema Wismut - Erkenntnisstand und Perspektiven [in German]
Abstract in English, French and Spanish. Topics: radon; conference; exposure; Germany; lung cancer; medical prevention; medical supervision; role of insurance institutions; silica; silicosis; uranium mining.
Hauptverband der gewerblichen Berufsgenossenschaften (HVBG), Alte Heerstrasse 111, 53754 Sankt Augustin, Germany, Dec. 1997. 228p. Illus. Bibl.ref.
Zuskin E., Mustajbegovic J., Schachter E.N., Doko-Jelinic J.
Respiratory function of textile workers employed in dyeing cotton and wool fibers
Topics: asthma; chronic bronchitis; Croatia; determination in air; dyeing; dyes; dyspnoea; epidemiologic study; harmful substances; irritation; pulmonary function; respiratory diseases; rhinitis; sinusitis; smoking; textile industry; ventilatory capacity.
American Journal of Industrial Medicine, Mar. 1997, Vol.31, No.3, p.344-352. 31 ref.
Zuskin E., Mustajbegovic J., Schachter E.N., Kern J., Pavicic D.
Respiratory function in vineyard and orchard workers
Topics: agriculture; chronic bronchitis; Croatia; dyspnoea; epidemiologic study; length of exposure; orchards; pulmonary function; respiratory diseases; smoking; ventilatory capacity; vineyards.
American Journal of Industrial Medicine, Feb. 1997, Vol.31, No.2, p.250-255. 30 ref.
Leclerc A., et al.
Sinonasal cancer and occupation: Results from the reanalysis of twelve case-control studies
Topics: agriculture; case-control study; drivers; food industry; literature survey; nasal cancer; occupation disease relation; road transport; textile industry.
American Journal of Industrial Medicine, Feb. 1997, Vol.31, No.2, p.153-165. 32 ref.
Kreiss K., Cox-Ganser J.
Metalworking fluid-associated hypersensitivity pneumonitis: A workshop summary
Topics: allergic respiratory disorders; bacteria; bacterial toxins; coolants; epidemiologic study; extrinsic allergic alveolitis; fungi; medical supervision; metalworking industry; microorganisms; pulmonary granulomatosis; respiratory diseases.
American Journal of Industrial Medicine, Oct. 1997, Vol.32, No.4, p.423-432. 31 ref.
Radiographic asbestosis is not a prerequisite for asbestos-associated lung cancer in Ontario asbestos-cement workers
Topics: asbestos cement industry; asbestosis; Canada; asbestos; chest radiography; epidemiologic study; latency; length of exposure; lung cancer; mortality; Ontario; pleural thickening; radiographic interpretation; smoking.
American Journal of Industrial Medicine, Oct. 1997, Vol.32, No.4, p.341-348. Illus. 15 ref.
Rosenman K.D., Reilly M.J., Kalinowski D.
Work-related asthma and respiratory symptoms among workers exposed to metal-working fluids
Topics: amines; asthma; chronic bronchitis; coolants; cutting fluids; determination in air; length of exposure; metalworking industry; oil mist; respiratory diseases; respiratory impairment; smoking; survey; USA.
American Journal of Industrial Medicine, Oct. 1997, Vol.32, No.4, p.325-331. 10 ref.
Glencross P.M., Weinberg J.M., Ibrahim J.G., Christiani D.C.
Loss of lung function among sheet metal workers: Ten-year study
Topics: asbestos; chest radiography; length of exposure; long-term study; metalworking industry; pleural diseases; pulmonary function; respiratory impairment; sheet-metal working; shipbuilding industry; smoking; spirometry; USA.
American Journal of Industrial Medicine, Nov. 1997, Vol.32, No.5, p.460-466. 33 ref.
Greaves I.A., Eisen E.A., Smith T.J., Pothier L.J., Kriebel D., Woskie S.R., Kennedy S.M., Shalat S., Monson R.R.
Respiratory health of automobile workers exposed to metal-working fluid aerosols: Respiratory symptoms
Topics: aerosols; asthma; chronic bronchitis; cutting fluids; dyspnoea; exposure evaluation; functional respiratory disorders; machining; motor vehicle industry; oil mist; personal sampling; questionnaire survey; respiratory diseases; USA.
American Journal of Industrial Medicine, Nov. 1997, Vol.32, No.5, p.450-459. 36 ref.
AbuDhaise B.A., Rabi A.Z., Zwairy M.A.A., Hader A.F.E., Qaderi S.E.
Pulmonary manifestations in cement workers in Jordan
Topics: airborne dust; asthma; cement industry; cement; chronic bronchitis; dyspnoea; exposure evaluation; Jordan; pulmonary function; questionnaire survey; respiratory diseases; smoking; spirometry.
International Journal of Occupational Medicine and Environmental Health, 1997, Vol.10, No.4, p.417-428. 22 ref.
Honma K., Chiyotani K., Kimura K.
Silicosis, mixed dust pneumoconiosis and lung cancer
Topics: autopsy; carcinogenic effects; carcinoma; dose-response relationship; histopathology; Japan; lung cancer; lung diseases; mixed dust pneumoconiosis; older workers; pneumoconiosis; silicosis; smoking.
American Journal of Industrial Medicine, Dec. 1997, Vol.32, No.6, p.595-599. Illus. 19 ref.
Harland A., Delzell E., Lally C., Rotimi C., Oestenstad K.
A case-control study of lung cancer at a foundry and two engine plants
Topics: carcinogens; case-control study; dose-response relationship; foundries; iron and steel industry; job-exposure relation; length of service; long-term exposure; lung cancer; machinery industry; mortality; smoking; USA.
American Journal of Industrial Medicine, Apr. 1997, Vol.31, No.4, p.414-421. 23 ref.
Sprince N.L., Thorne P.S., Popendorf W., Zwerling C., Miller E.R., DeKoster J.A.
Respiratory symptoms and lung function abnormalities among machine operators in automobile production
Topics: aerosols; bacterial toxins; cross-sectional study; cutting fluids; determination in air; dose-response relationship; fungi; metalworking industry; motor vehicle industry; pulmonary function; respiratory diseases; respiratory function tests; respiratory impairment; USA.
American Journal of Industrial Medicine, Apr. 1997, Vol.31, No.4, p.403-413. 29 ref.
Demers P.A, Teschke K., Kennedy S.M.
What to do about softwood? A review of respiratory effects and recommendations regarding exposure limits
Topics: asthma; carcinogens; carpentry; dose-response relationship; dust measurement; epidemiologic study; limitation of exposure; literature survey; nasal cancer; particle size determination; respiratory diseases; sawmilling industry; softwoods; wood dust; woodworking industry.
American Journal of Industrial Medicine, Apr. 1997, Vol.31, No.4, p.385-398. 73 ref.
Cherry N.M., Niven R.M., Burgess G., Robinson J., Wall S., Woerfel P.
Health and Safety Executive
Chronic bronchitis and lung function abnormalities in foundry workers
Topics: airborne dust; chronic bronchitis; epidemiologic study; exposure evaluation; foundries; job-exposure relation; length of exposure; one-second forced expiratory volume; pulmonary function; report; respiratory impairment; United Kingdom.
HSE Books, P.O. Box 1999, Sudbury, Suffolk CO10 6FS, United Kingdom, 1997. 72p. 6 ref. Price: GBP 25.00.
Massin N., Bohadana A.B., Wild P., Goutet P., Kirstette H., Toamain J.P.
Study of bronchial reactivity and respiratory symptoms of workers exposed to oil mists
Etude de la réactivité bronchique et des symptômes respiratoires des salariés exposés aux brouillards d'huile [in French]
Topics: cross-sectional study; determination in air; dose-response relationship; exposure evaluation; France; mineral oils; oil mist; pulmonary function; pulmonary ventilation; respiratory impairment; spirometry.
Documents pour le médecin du travail, 3rd Quarter 1997, No.71, p.237-241. 17 ref.
Moulin J.J., Perdrix A., Lasfargues G., Romazini S., Bozec C., Deguerry P., Pellet F., Peltier A., Wild P.
Epidemiologic study of mortality in the hard metal industry in France
Etude épidémiologique de mortalité dans l'industrie productrice de métaux durs en France [in French]
Topics: tungsten carbide 1:1; case-control study; cobalt; confounding factors; exposure evaluation; France; length of exposure; lung cancer; mortality; powder metallurgy; smoking.
Cahiers de notes documentaires - Hygiène et sécurité du travail, 3rd Quarter 1997, No.168, Note No.2057-168-97, p.411-428. Illus. 35 ref.
Luce D., Gérin M., Morcet J.F., Leclerc A.
Sinonasal cancer and occupational exposure to textile dust
Topics: airborne dust; case-control study; cotton; exposure evaluation; France; length of exposure; nasal cancer; sex-linked differences; synthetic fibres; textile industry; wool.
American Journal of Industrial Medicine, Sep. 1997, Vol.32, No.3, p.205-210. 15 ref.
Woellner R.C., Hall S., Greaves I., Schoenwetter W.F.
Epidemic of asthma in a wood products plant using methylene diphenyl diisocyanate
Topics: asthma; diphenylmethane diisocyanate; dyspnoea; respiratory function tests; respiratory impairment; sensitization; USA; woodworking industry.
American Journal of Industrial Medicine, Jan. 1997, Vol.31, No.1, p.56-63. Illus. 16 ref.
Zuskin E., Mustajbegovic J., Schachter E.N., Doko-Jelinic J., Bradic V.
Respiratory function in shoe manufacturing workers
Topics: aerosols; air sampling; asthma; benzene; chronic bronchitis; Croatia; dyspnoea; epidemiologic study; eye irritation; length of exposure; migraine; organic solvents; pulmonary function; respirable dust; respiratory function tests; respiratory impairment; rhinitis; shoe industry; sinusitis; ventilatory capacity; women.
American Journal of Industrial Medicine, Jan. 1997, Vol.31, No.1, p.50-55. 25 ref.
Sama S., Kriebel D., Woskie S., Eisen E., Wegman D., Virji M.A.
A field investigation of the acute respiratory effects of metal working fluids - II. Effects of airborne sulfur exposures
Topics: aerosols; cross-sectional study; cutting fluids; determination in air; exposure evaluation; functional respiratory disorders; irritants; metalworking industry; oil mist; pulmonary function; respirable dust; spirometry; sulfur; USA; ventilatory capacity.
American Journal of Industrial Medicine, June 1997, Vol.31, No.6, p.767-776. 28 ref.
Kriebel D., Sama S.R., Woskie S., Christiani D.C., Eisen E.A., Hammond S.K., Milton D.K., Smith M., Virji A.M.
A field investigation of the acute respiratory effects of metal working fluids - I. Effects of aerosol exposures
Topics: aerosols; bacteria; bacterial toxins; cross-sectional study; cutting fluids; determination in air; exposure evaluation; functional respiratory disorders; metalworking industry; oil mist; pulmonary function; respirable dust; spirometry; USA; ventilatory capacity.
American Journal of Industrial Medicine, June 1997, Vol.31, No.6, p.756-766. 25 ref.
Torén K., Hörte L.G.
Asthma mortality and occupation in Sweden 1981-1992
Topics: agriculture; asthma; drivers; epidemiologic study; hairdressing; mortality; occupation disease relation; smoking; Sweden.
American Journal of Industrial Medicine, June 1997, Vol.31, No.6, p.678-681. 14 ref.
Allergic reactions to workplace allergens
Topics: allergens; allergic asthma; allergic rhinitis; allergy tests; asthma; diagnosis; immunology; individual susceptibility; latex; literature survey; sensitization dermatitis; serological reactions.
Journal of the American Medical Association, 10 Dec. 1997, Vol.278, No.22, p.1907-1913. Illus. 89 ref.
Adverse effects of crystalline silica exposure
Official statement of the American Thoracic Society. Topics: chronic bronchitis; free silica; literature survey; lung cancer; obstructive ventilatory impairment; respiratory diseases; silica; silicosis.
American Journal of Respiratory and Critical Care Medicine, Feb. 1997, Vol.155, No.2, p.761-768. 146 ref.
McLean A.N., Patel K.R.
Clinical features and epidemiology of malignant pleural mesothelioma in west Glasgow 1987-1992
Topics: asbestos; epidemiologic study; morbidity; pleural mesothelioma; Scotland; shipbuilding industry; United Kingdom.
Scottish Medical Journal, Apr. 1997, Vol.42, p.37-39. 15 ref.
Ulfberg J., Carter N., Talbäck M., Edling C.
Occupational exposure to organic solvents and sleep-disordered breathing
Topics: apnoea; exposure evaluation; functional respiratory disorders; organic solvents; questionnaire survey; sleep disturbances; Sweden.
Neuroepidemiology, 1997, Vol.16, p.317-326. Illus. 27 ref.
Case B.W., Dufresne A.
Asbestos, asbestosis, and lung cancer: Observations in Quebec chrysotile workers
Topics: asbestos mining; asbestos; asbestosis; Canada; chrysotile; compensation of occupational diseases; diagnosis; epidemiologic study; exposure evaluation; lung cancer; Quebec; smoking.
Environmental Health Perspectives, Sep. 1997, Vol.105, Suppl.5, p.1113-1119. Illus. 15 ref.
Giarelli L., Grandi G., Bianchi C.
Malignant mesothelioma of the pleura in the Trieste-Monfalcone area, with particular regard to shipyard workers
Topics: asbestos; epidemiologic study; Italy; latency; pleural mesothelioma; shipbuilding industry.
Medicina del lavoro, July-Aug. 1997, Vol.88, No.4, p.316-320. 18 ref.
Costantini A.S., Chellini E.
The experience of the mesothelioma registry of Tuscany in assessing health hazards associated with asbestos exposure
Topics: asbestos; epidemiologic study; Italy; occupation disease relation; pleural mesothelioma; sex-linked differences; textile industry; Tuscany.
Medicina del lavoro, July-Aug. 1997, Vol.88, No.4, p.310-315. Illus. 4 ref.
Magnani C., Ivaldi C., Botta M., Terracini B.
Pleural malignant mesothelioma and environmental asbestos exposure in Casale Monferrato, Piedmont. Preliminary analysis of a case-control study
Topics: asbestos processing industry; asbestos; case-control study; Italy; neighbourhood populations; Piedmont; pleural mesothelioma.
Medicina del lavoro, July-Aug. 1997, Vol.88, No.4, p.302-309. 8 ref.
Comba P., Di Paola M., Martuzzi M., Pirastu R.
Asbestos-related mortality in Italy: A geographical approach
Topics: asbestos; Italy; literature survey; lung cancer; mortality; pleural mesothelioma.
Medicina del lavoro, July-Aug. 1997, Vol.88, No.4, p.293-301. 48 ref.
Introduction: History of the use of asbestos
Topics: asbestos processing industry; asbestos; asbestosis; history; literature survey; lung cancer; lung diseases; mesothelioma.
Medicina del lavoro, July-Aug. 1997, Vol.88, No.4, p.288-292. 63 ref.
Churg A., Zay K., Li K.
Mechanisms of mineral dust-induced emphysema
Topics: animal experiments; asbestos; titanium dioxide; quartz; coal dust; emphysema; in vitro experiments; mineral dust; obstructive ventilatory impairment; pathogenesis; smoking.
Environmental Health Perspectives, Sep. 1997, Vol.105, Suppl. 5, p.1215-1218. Illus. 20 ref.
Crinquand A., Boudret G., Laureillard J., Joly N., Gillet A., Iwatsubo Y., Brochard P., Choudat D., Ameille J.
Study of the respiratory morbidity in metal polishers exposed to crystalline iron dust
Etude de la morbidité respiratoire de polisseurs de métaux exposés à des poussières de fer cristallin [in French]
Topics: case-control study; chest radiography; France; iron oxide; length of exposure; male workers; manufacture of musical instruments; metallic oxides; one-second forced expiratory volume; questionnaire survey; respiratory diseases; siderosis; smoking; statistical aspects; vital capacity.
Archives des maladies professionnelles et de médecine du travail, Dec. 1997, Vol.58, No.8, p.648-653. 14 ref.
Joly N., Martin-Silva B., Choudat D., Vicrey C., Rossignol C., Conso F.
Symptoms and respiratory function values in a group of bakers/pastrycooks in the Poitou-Charentes region
Symptômes et fonction respiratoires des artisans boulangers de la région Poitou-Charentes [in French]
Topics: allergic respiratory disorders; allergies; asthma; bakery products industry; case-control study; flour; France; male workers; one-second forced expiratory volume; questionnaire survey; rhinitis; smoking; vital capacity.
Archives des maladies professionnelles et de médecine du travail, Dec. 1997, Vol.58, No.8, p.641-647. 17 ref.
Augenti M., Galluzzo V., Nava C.
Allergic disease caused by enzymes. A case of asthma due to pectinase (polygalacturonase) exposure
La patologia allergica da enzimi: descrizione di un caso di asma da pectinase (poligalatturonasi) [in Italian]
Topics: allergens; allergic asthma; asthma; case study; enzymes; food additives; Italy; sensitization.
Medicina del lavoro, Nov.-Dec. 1997, Vol.88, No.6, p.489-494. 15 ref.
Massin N., Mellinger M.C., Barthélémy J.F., Goutet P., Wild P., Stempfer J.C.
Respiratory symptoms, pulmonary function impairments and exposure assessment to silica dusts among industrial furnace repairmen
Symptômes, anomalies fonctionnelles respiratoires et évaluation de l'exposition aux poussières silicogènes chez les maçons fumistes [in French]
Topics: comparative study; functional respiratory disorders; furnace repairs; health hazards; one-second forced expiratory volume; questionnaire survey; respirable dust; silica; silicosis.
Archives des maladies professionnelles et de médecine du travail, 1997, Vol.58, No.6, p.499-505. 19 ref.
Buick J.B., Todd G.R.G.
Concomitant alveolitis and asthma following exposure to triphenylmethane triisocyanate
Topics: asthma; case study; extrinsic allergic alveolitis; respiratory function tests; triphenylmethane triisocyanate.
Occupational Medicine, Nov. 1997, Vol.47, No.8, p.504-506. 6 ref.
Palmer K., Crane G.
Respiratory disease in workers exposed to colophony solder flux fumes: Continuing health concerns
Topics: asthma; colophony; exposure evaluation; questionnaire survey; respiratory diseases; respiratory function tests; soldering and brazing; soldering flux; United Kingdom; welding fumes; women.
Occupational Medicine, Nov. 1997, Vol.47, No.8, p.491-496. 14 ref.
Jagielo P.J., et al.
Pentoxifylline does not alter the response to inhaled grain dust
To investigate the effects of pentoxifylline (PTX) following acute grain dust inhalation, ten subjects with normal airway reactivity were treated with PTX or placebo, followed by corn dust extract inhalation. Respiratory symptoms and declines in respiratory function occurred following grain dust exposure in both groups, although differences were not significant. Results suggest that pretreatment with PTX does not alter the acute physiologic or inflammatory events following exposure to inhaled grain dust.
Chest, May 1997, Vol.111, No.5, p.1429-1435. Illus. 34 ref.
Occupational asthma: A survey of epidemiology and criteria for the evaluation of the permanent damage
L'asma professionale: Considerazioni sull'epidemiologia e sui criteri di valutazione del danno [in Italian]
Data on occupational asthma in Italy are reviewed. An estimated 500-600 cases occur per year. The medical and legal criteria used for diagnosis and compensation purposes are reviewed and criteria are proposed for the assessment of residual permanent damage. The importance of early diagnosis, medical rehabilitation and retraining of asthma victims is stressed.
Medicina del lavoro, Jan.-Feb. 1997, Vol.88, No.1, p.3-12. 33 ref.
Venables K.M., Chan-Yeung M.
The causes, clinical features and management of occupational asthma are reviewed. Common causative agents are listed and pathological changes resulting in airway inflammation and hyperresponsiveness are outlined. Clinical features, epidemiological aspects, diagnosis, management of the disease and impairment assessment are discussed. Primary prevention measures include elimination of the agent from the workplace, reduction of exposure, and exclusion of susceptible individuals.
Lancet, May 1997, Vol.349, No.9063, p.1465-1469. Illus. 36 ref.
Health and Safety Executive
Asthmagen? Critical assessments of the evidence for agents implicated in occupational asthma
This document provides data on 29 substances considered to meet European Union criteria for classification as a respiratory sensitizer (a cause of asthma). Data on three further substances considered not to meet these criteria are also presented. Results of studies providing evidence of work-related asthma are summarized along with supporting data. It is intended that assessments of the asthmagenic potential of other industrial chemicals and substances of biological origin will be added in due course.
HSE Books, P.O. Box 1999, Sudbury, Suffolk CO10 6FS, United Kingdom, 1997. 94p. (loose-leaf binder). Bibl.ref. Price: GBP 25.00.
Fine J.M., et al.
Metal fume fever: Characterization of clinical and plasma IL-6 responses in controlled human exposures to zinc oxide fume at and below the threshold limit value
In a study of the clinical effects of exposure to low concentrations of zinc oxide, 13 subjects were exposed to air or to 2.5 or 5mg/m3 of furnace-generated zinc oxide fume for 2h. Symptoms and temperature were recorded and blood samples were taken after exposure. The rise in oral temperature was greater after inhalation of zinc oxide than after air inhalation. Plasma levels of interleukin 6 (IL-6), a pyrogen, were significantly elevated after exposure to 5mg/m3 of zinc oxide. The predominant symptoms reported were myalgias, cough and fatigue. Inhalation of zinc oxide for 2h at the current threshold limit value of 5mg/m3 produces fever, symptoms and elevation in plasma IL-6 levels.
Journal of Occupational and Environmental Medicine, Aug. 1997, Vol.39, No.8, p.722-726. Illus. 20 ref.
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