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Base de datos CISDOC

ID (ISN) del documento75736
Número CIS 00-1604
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 1998
Número de serie
Autor(es) Gustavsson P., Jakobsson R., Johansson H., Lewin F., Norell S., Rutkvist L.E.
Título Occupational exposures and squamous cell carcinoma of the oral cavity, pharynx, larynx, and oesophagus: A case-control study in Sweden
Información bibliográfica June 1998, Vol.55, No.6, p.393-400. 27 ref.
Resumen This community-based case-referent study was initiated to investigate aetiological factors for squamous cell carcinoma of the upper gastrointestinal tract. The study was based on all Swedish men aged 40-79 living in two regions of Sweden during 1988-90. Exposure to asbestos was associated with an increased risk of laryngeal cancer, and a dose-response relation was present. The RR was 1.8 in the highest exposure group. More than eight years of exposure to welding fumes was associated with an increased risk of pharyngeal cancer (RR=2.3 (1.1 to 4.7)), and laryngeal cancer (RR=2.0). There were indications of a dose-response for duration of exposure. Associations were also found for high exposure to polycyclic aromatic hydrocarbons (PAHs) and oesophageal cancer (RR=1.9). Exposure to wood dust was associated with a decreased risk of cancer at the studied sites. The study indicates that welding may cause an increased risk of pharyngeal as well as laryngeal cancer. The findings corroborate an association between exposure to PAHs and oesophageal cancer.
Descriptores (primarios) cáncer de esófago; cáncer de laringe; exposición; cáncer de boca; cáncer de faringe
Descriptores (secundarios) formaldehido; polvo de madera; Suecia; hidrocarburos aromáticos; amianto; relación dosis-respuesta; polvos respirables; humos de soldadura; hidrocarburos policíclicos; estudio del caso y testigo; etiología
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaSuecia
Tema(s) Patología profesional
Broad subject area(s) Medicina del trabajo, epidemiología
Navegación por categoria(s) Mouth and teeth diseases
Diseases of the respiratory system (except for pneumoconiosis & similar)
Gastrointestinal diseases