| ID (ISN) del documento | 61584 |
| Número CIS |
94-287 |
| ISSN - Título de la serie |
0096-1736 - Journal of Occupational Medicine |
| Año |
1993 |
| Número de serie |
|
| Autor(es) |
Grammer L.C., Shaughnessy M.A., Davis R.A. |
| Título |
Exposure to TMXDIR (meta) aliphatic isocyanate and TMIR (meta) unsaturated aliphatic isocyanate - Clinical and immunologic evaluation of 96 workers |
| Información bibliográfica |
Mar. 1993, Vol.35, No.3, p.287-290. 15 ref. |
| Resumen |
Ninety-six workers employed at facilities that manufacture or use TMXDI (meta) aliphatic isocyanate and TMI (meta) unsaturated aliphatic isocyanate underwent immunological tests and responded to a questionnaire designed to identify symptoms compatible with work-related syndromes such as asthma and hypersensitivity pneumonitis. There were no workers with immunologically induced disease due to TMI isocyanate or TMXDI isocyanate nor were there any workers whose questionnaires suggested a new onset of asthma. Approximately 40% of workers experienced some irritant symptoms, mostly upper respiratory or ocular. One worker had low-level IgE antibody against TMXDI-HSA (human serum albumin) but had no work-related respiratory symptoms. Very low-level IgG against TMI-HSA or TMXDI-HSA was present in 7% of workers, all of whom were in the high exposure category. |
| Descriptores (primarios) |
isocianatos; síntomas; reacciones serológicas; exposición; enfermedades respiratorias |
| Descriptores (secundarios) |
muestreo individual; industria química; hipersensibilidad; asma; estudio transversal; anticuerpos |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Estados Unidos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Cyano compounds
Diseases of the respiratory system (except for pneumoconiosis & similar)
Isocyanates
|
