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Base de datos CISDOC

ID (ISN) del documento61332
Número CIS 93-1950
ISSN - Título de la serie 0867-8383 - Polish Journal of Occupational Medicine and Environmental Health
Año 1993
Número de serie
Autor(es) Halkova Z., Zaykov C., Antov G., Mihaylova A., Mircheva V., Dinoeva S., Chipilska L.
Título Experimental study of subacute oral, dermal and inhalation toxicity of Bulmoscide preparation
Información bibliográfica 1993, Vol.6, No.1, p.19-25. Illus. 26 ref.
Resumen The microbial product Bulmoscide is a new Bulgarian selective insecticide. The purpose of this study was to give the toxicological characteristics of subacute oral, dermal and inhalation exposure of microbial preparation Bulmoscide, which is based on bacterium Bacillus thuringiensis, serotype H-14. The study was performed on sexually mature Wistar rats of both sexes. No significant changes in non-specific, clinico-laboratory and biochemical parameters as well as morphological examinations in any tested groups compared to the control groups were revealed. The doses 110mg/kg (1.32 x 109 sp/kg) at oral administration during 90 days, 3000mg/kg (3.6 x 1010 sp/kg) in 21 day dermal application and maximum attainable concentration of dust aerosol 18mg/m3 (2.2 x 108 sp/m3) during a 30 day inhalation exposure are "no toxic effect" levels. On the basis of these data, Bulmoscide has been determined to be of low toxicity, presenting little hazard in terms of the Hygiene Classification of pesticides.
Descriptores (primarios) efectos tóxicos; bacterias; pesticidas; toxicidad por inhalación; valoración de la toxicidad; toxicidad percutánea; insecticidas biológicos
Descriptores (secundarios) Bulgaria; investigaciones en el animal; substancias tóxicas
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaBulgaria
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Agricultural chemicals