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ID (ISN) del documento60754
Número CIS 93-1612
ISSN - Título de la serie 0160-2748 - Neurotoxicology
Año 1992
Número de serie
Autor(es) Discalzi G.L., Capellaro F., Bottalo L., Fabbro D., Mocellini A.
Título Auditory brainstem evoked potentials (BAEPs) in lead-exposed workers
Información bibliográfica Spring 1992, Vol.13, No.1, p.207-209. 6 ref.
Resumen Brainstem auditory evoked potentials (BAEPs) were recorded in 49 lead-exposed workers, and in an equal number controls never exposed to neurotoxic substances. The mean duration of lead exposure was 7.4yrs (Standard Deviation (SD) 5.6). An averaged lead blood level (PbB) was based on the levels of the three previous years (PbBm). Blood lead concentration was analysed in the morning of the experimental day (PbBc). Interpeak latency differences (IPLD) I-V, I-III, and III-V were considered. The mean PbBc level was 54.6µg/dL (SD 16.1) while the mean PbBm level was 53.5µg/dL (SD 15.9). Lead exposed workers showed a significant prolongation of IPLDs. IPLD I-V was longer in the subgroup with PbBm >50µg/dL (4.06 versus 3.98, CI 95% 0.00-0.16). These results are consistent with literature data and show that BAEPs may be a sensitive detector of subclinical lead effects on brainstem auditory pathways.
Descriptores (primarios) efectos neurotóxicos; exámenes audiométricos; plomo; sistema nervioso central
Descriptores (secundarios) diagnostico precoz; dosificación en la sangre; periodo de latencia
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaItalia
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Diseases of the nervous system
Lead and compounds
Inorganic substances