| ID (ISN) del documento | 59478 |
| Número CIS |
93-254 |
| ISSN - Título de la serie |
0355-3140 - Scandinavian Journal of Work, Environment and Health |
| Año |
1992 |
| Número de serie |
|
| Autor(es) |
Prescott E., Netterstrøm B., Faber J., Hegedüs L., Suadicani P., Christensen J.M. |
| Título |
Effect of occupational exposure to cobalt blue dyes on the thyroid volume and function of female plate painters |
| Información bibliográfica |
Apr. 1992, Vol.18, No.2, p.101-104. 17 ref. |
| Resumen |
The effect of industrial cobalt exposure on thyroid volume and function was determined for 61 female plate painters exposed to cobalt blue dyes in two Danish porcelain factories and 48 unexposed referents. Thyroid volume was determined by ultrasonography. The cobalt blue dyes were used in one of two forms, cobalt aluminate (insoluble) and cobalt-zinc silicate (semisoluble). Only the subjects exposed to semisoluble cobalt had a significantly increased urinary cobalt content (1.17µg.mmol-1 versus 0.13µg.mmol-1, p<0.0001). These subjects also had increased levels of serum thyroxine (T4) and free thyroxine (FT4I) (p=0.0001 and 0.0029, respectively) unaltered serum thyroid stimulating hormone (TSH), and marginally reduced 3,5,3'-triiodothyronine (T3), whereas thyroid volume tended to be lower (p=0.14). The group exposed to insoluble cobalt did not differ significantly in any thyroid-related parameters. No correlation between urinary cobalt and FT4I or thyroid volume was found. The study demonstrates an effect of cobalt on thyroid hormone metabolism. |
| Descriptores (primarios) |
cobalto; tintes; fabricación de porcelanas y loza; pintura; mujeres; trastornos tiroideos |
| Descriptores (secundarios) |
glándula tiroides; función tiroidea; estudio comparado; dosificación en la orina; exámenes por ultrasonidos; tests de exposición |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Dinamarca |
| Tema(s) |
Materiales de construcción, vidrio, cerámica
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Inorganic substances
Endocrine diseases
Glass, pottery and related materials
Surface treatment
|
