| ID (ISN) del documento | 59333 |
| Número CIS |
93-117 |
| ISSN - Título de la serie |
0096-1736 - Journal of Occupational Medicine |
| Año |
1992 |
| Número de serie |
|
| Autor(es) |
Pelmear P.L., Roos J.O., Maehle W.M. |
| Título |
Occupationally-induced scleroderma |
| Información bibliográfica |
Jan. 1992, Vol.34, No.1, p.20-25. Illus. 44 ref. |
| Resumen |
Systemic sclerosis or scleroderma is an uncommon multisystem disease with a reported incidence of two to 12 cases per million people per year. The clinical and pathological features can be grouped into three main categories: those related to fibrosis, to vascular abnormalities, and to immunological abnormalities. Cutaneous features dominate the patients' appearance, and Raynaud's phenomenon is an early symptom. A possible association between scleroderma and workers exposed to hand-arm vibration and/or silica has been suggested by reports in the literature since the turn of the century. A further four patients with collagen disease are reported here. Three were occupationally exposed to both hand-arm vibration and silica, the fourth to hand-arm vibration alone. In conjunction with previously reported cases, this supports the hypothesis that collagen disease may be attributable to occupation in hypersusceptible persons. |
| Descriptores (primarios) |
esclerodermia; dermatosis; relación entre la profesión y la enfermedad |
| Descriptores (secundarios) |
estudio de caso; resonancia; sílice; síndrome de Raynaud; patogénesis; colagenosis; fibrosis; reacciones serológicas; disfunción vascular |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Canadá |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Skin diseases
|
