| ID (ISN) del documento | 58345 |
| Número CIS |
92-1264 |
| ISBN(s) |
3-89429-124-9 |
| Año |
1991 |
| Número de serie |
Fb 638
|
| Autor(es) |
Pott F., Rippe R.M., Roller M., Rosenbruch M., Huth F.
Bundesanstalt für Arbeitsschutz |
| Título |
Comparative studies on the carcinogenicity of nickel, different nickel compounds and nickel alloys |
| Título original |
Vergleichende Untersuchungen über die Kanzerogenität verschiedener Nickelverbindungen und Nickellegierungen [en alemán] |
| Información bibliográfica |
Wirtschaftsverlag NW, Postfach 10 11 10, Am Alten Hafen 113-115, D-W-2850 Bremerhaven 1, Germany, 1991. 59p. Illus. 45 ref. |
| Resumen |
This study is divided into two sections. I. - Bibliographical review (in tabular form) of the carcinogenic effects on animals of nickel (Ni), nickel compounds and nickel alloys. II - Assessment, through animal experiments, of the carcinogenicity of nickel powder, and of six nickel compounds (chloride, sulfate, acetate, carbonate, subsulfide, oxide) as well as 3 nickel alloys. Highly soluble nickel compounds (Ni-chloride, -sulfate, -acetate) were very toxic but only weakly carcinogenic. Ni-subsulfide showed a lower toxicity but the strongest carcinogenicity of all tested substances (inducement of sarcomas and mesotheliomas in 56% of animals from 6mg Ni). Higher doses (25 to 50mg Ni) of two nickel alloys containing 50% or 66% of nickel oxide produced a carcinogenic but no toxic effect. 100mg Ni injected with a nickel alloy containing 29% Ni and 160mg of two iron oxides were not proven to be carcinogenic. Summaries in English, French and German. |
| Descriptores (primarios) |
aleaciones de níquel; substancias cancerígenas; efectos cancerígenos; níquel; valoración del riesgo; níquel y sus compuestos |
| Descriptores (secundarios) |
revisión bibliográfica; sulfuro de níquel; sulfato de níquel; carbonato de níquel; acetato de níquel; investigaciones en el animal; cloruro de níquel(II); óxido de níquel(II) |
| Tipo de documento |
E - Libros, informes, actas |
| País / Estado o Provincia | Alemania |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Inorganic substances
Risk evaluation
Nickel and compounds
|
