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Base de datos CISDOC

ID (ISN) del documento58120
Número CIS 92-832
ISSN - Título de la serie 0096-1736 - Journal of Occupational Medicine
Año 1991
Número de serie
Autor(es) Hodgkins D.G., Robins T.G., Hinkamp D.L., Schork M.A., Levine S.P., Krebs W.H.
Título The effect of airborne lead particle size on worker blood-lead levels: An empirical study of battery workers
Información bibliográfica Dec. 1991, Vol.33, No.12, p.1265-1273. 28 ref.
Resumen Workers in a lead-acid battery plant were studied for the influence of lead aerosol size on lead-in-blood (PbB) levels. A multiple linear regression analysis based on particle size assumptions made in a model to help select the permissible exposure level for lead showed no improvement in prediction of PbB over that already present without any consideration of particle size. However, when deposition models developed by Heyder et al were used in which the lead aerosol was separated into alveolar and extra-alveolar fractions, corresponding to what is considered respirable and ingestible lead, the coefficient of determination associated with the fractionated lead particulate increased approximately 25% over that attributable to only the total lead concentration. The deposition model resulted in ratios of the coefficients for the respirable to ingestible lead contributions to PbB that appeared to agree with experimental data, suggesting approximately a 10 to 1 ratio in absorbtion efficiency of the lung versus the gastrointestinal tract.
Descriptores (primarios) polvos en suspensión aérea; reparto granulométrico; plomo; dosificación en la sangre; descarga de partículas; aerosoles; polvos respirables
Descriptores (secundarios) pulmones; tubo digestivo; Estados Unidos; fabricación de pilas y acumuladores; ingestión; inhalación; vías de penetración
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaEstados Unidos
Tema(s) Polvos, aerosoles
Broad subject area(s) Medicina del trabajo, epidemiología
Navegación por categoria(s) Lead and compounds
Inorganic substances