| ID (ISN) del documento | 57655 |
| Número CIS |
92-552 |
| ISSN - Título de la serie |
0025-7818 - Medicina del lavoro |
| Año |
1990 |
| Número de serie |
|
| Autor(es) |
Bolla I., Gariboldi L.M., Gabrielli M., Baldo D., Romanelli A., Tuberti E., Magnani F. |
| Título |
Nasal diseases due to occupational exposure to chromium in the electroplating industry - Cytomorphological aspects |
| Título original |
Rinopatia da esposizione professionale a cromo nell'industria galvanica - Aspetti citomorfologici [en italiano] |
| Información bibliográfica |
Sep.-Oct. 1990, Vol.81, No.5, p.390-398. Illus. 20 ref. |
| Resumen |
26 workers were studied (9 chrome-platers exposed to chromium dioxide and 17 workers exposed to metallic chromium dust) in order to investigate the macroscopic and cytological changes of the nasal mucosa due to exposure to water-soluble hexavalent chromium or to metallic chromium dust in the electroplating industry and the role of different valencies in the onset of nasal disease. Experimental and epidemiological data have shown that hexavalent chromium, which is a strong oxidiser, induces more noticeable toxic effects on tissues and mucous membranes than do other compounds. The correlation between the degree of local toxic effects and the chemical state of chromium was demonstrated in both the macro- and the microscopic investigations and in particular in the cytological examinations: cases of atypia were found only in workers exposed to hexavalent chromium. Evidence of atypia raises the question of whether hexavalent chromium may act as a carcinogenic agent on the rhinosinusal mucosa. For this reason, the introduction of cytological nasal examination in health surveillance programmes for this category of workers acquires considerable importance. Sample collection from the nasal mucosa by brushing is the method of choice since it is simple, non-invasive and gives good diagnostic results. |
| Descriptores (primarios) |
cáncer nasal; electrochapado; dióxido de cromo; efectos citológicos; cromo; enfermedades de las mucosas |
| Descriptores (secundarios) |
substancias cancerígenas; encuesta epidemiológica; Italia; polvos minerales |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Italia |
| Tema(s) |
Metalurgia, trabajo de los metales
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Inorganic substances
Skin diseases
Diseases of the respiratory system (except for pneumoconiosis & similar)
Surface treatment
|
