| ID (ISN) del documento | 56789 |
| Número CIS |
91-1640 |
| ISBN(s) |
0-11-885613-8 |
| Año |
1990 |
| Número de serie |
Toxicity Review TR 24
|
| Autor(es) |
Payne M.P., Delic J.I., Bell G.M. |
| Título |
Ammonia; 1-Chloro-2,3-epoxypropane (Epichlorohydrin); Carcinogenicity of cadmium and its compounds |
| Información bibliográfica |
HMSO Books, P.O. Box 276, London SW8 5DT, United Kingdom, 1990. 12p. + 30p. + 14p. 90 + 122 + 26 ref. Price: GBP 9.00. |
| Resumen |
Toxicity review of ammonia (NH3): main effect is concentration-dependent irritation or corrosion of mucous membranes; at concentrations above 1000ppm NH3 may be lethal in animals; chronic exposure at 100ppm or more may produce severe lesions in animals; in humans accidental exposure to high concentrations (>200ppm) may lead to severe respiratory tract, lung and eye damage and even death; at <200ppm reported effects in humans include skin, eye and upper respiratory tract irritation; no clear evidence of genotoxic, carcinogenic or embryotoxic effects. Toxicity review of 1-chloro-2,3-epoxypropane (epichlorohydrin, ECH), a colourless, volatile liquid at room temperature with a chloroform-like odour: moderate toxicity and irritation effects, with little or no evidence for genotoxic, carcinogenic or reproductive effects. Carcinogenicity review of cadmium and its compounds (update of a previous review, see CIS 84-505): though cadmium fume and aerosols can be highly toxic, there is no conclusive evidence of an association between cadmium exposure and cancer. |
| Descriptores (primarios) |
cadmio y sus compuestos; substancias irritantes; Reino Unido; cadmio; toxicología; epiclorohidrina; substancias tóxicas; amoniaco |
| Descriptores (secundarios) |
efectos tóxicos; revisión bibliográfica; tests de carcinogénesis; investigaciones en el animal; substancias cancerígenas |
| Tipo de documento |
E - Libros, informes, actas |
| País / Estado o Provincia | Reino Unido |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Inorganic substances
Ethers
Ethylene oxide
Cadmium and compounds
|
