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ID (ISN) del documento55720
Número CIS 91-576
ISBN(s) 0-442-00422-2
Año 1989
Número de serie
Autor(es) Hood R.D.
U.S. Environmental Protection Agency
Título Development toxicology: Risk assessment and the future
Información bibliográfica Van Nostrand Reinhold, 115 Fifth Ave., New York, NY 10003, USA; Chapman and Hall, 11 New Fetter Lane, London EC4P 4EE, United Kingdom, Dec. 1989. 279p. Illus. Approx. 810 ref. Index. Price: GBP 32.50.
Resumen Review of efforts to estimate the risk of developmental defects and disabilities in humans due to the exposure of parents to chemicals before conception, during pregnancy or during childhood. Emphasis is on areas of needed research identified by the US Environmental Protection Agency, including paternally mediated effects, nonbehavioural functional effects, pharmacokinetic and physiological models, structure-activity relationships and mathematical modelling. Carcinogenicity, interspecies differences and methodological issues are also discussed.
Descriptores (primarios) efectos esterilizantes; Estados Unidos; toxicología; tumores; efectos gonadotrópicos; efectos teratogénicos; valoración del riesgo
Descriptores (secundarios) efectos embriotóxicos; revisión bibliográfica; extrapolación del animal al hombre; predicción matemática; efectos neuropsíquicos; efectos cancerígenos; modelos matemáticos; efectos genéticos
Tipo de documento E - Libros, informes, actas
País / Estado o ProvinciaEstados Unidos
Tema(s) Patología profesional
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Risk evaluation