ID (ISN) del documento | 55336 |
Número CIS |
91-225 |
ISBN(s) |
92-4-157109-8 |
Año |
1990 |
Número de serie |
Environmental Health Criteria 109
|
Autor(es) |
International Programme on Chemical Safety (IPCS) |
Título |
Summary report on the evaluation of short-term tests for carcinogens (Collaborative study on In Vivo Tests) |
Información bibliográfica |
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1990. 96p. Illus. 15 ref. Price: CHF 13.00. |
Resumen |
This IPCS report describes criteria for the selection of an appropriate short-term in vivo test to determine the in vivo activity of established genotoxins and the selection of 4 test chemicals, the assays used, and the results of tests carried out on the selected chemicals. An assessment is made of the performance of the assays along with a selection of those considered to be most effective. Short-term in vivo tests have a vital role to play in the identification of those chemicals most likely to present a carcinogenic/mutagenic hazard. Detailed summaries in French and Spanish. |
Descriptores (primarios) |
mutágenos; substancias cancerígenas; PISSC; tests de carcinogénesis; valoración del riesgo; tests de mutagénesis; OMS |
Descriptores (secundarios) |
OIT; PNUMA; pireno; valoración del método; acetilamino-4 fluoreno; benzo(a)pireno; acetilamino-2 fluoreno |
Tipo de documento |
E - Libros, informes, actas |
Tema(s) |
Sustancias tóxicas y peligrosas
|
Broad subject area(s) |
Riesgos químicos
|
Navegación por categoria(s) |
Risk evaluation
|