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ID (ISN) del documento55282
Número CIS 91-202
ISSN - Título de la serie 0009-9309 - Clinical Toxicology
Año 1990
Número de serie
Autor(es) Klees J.E., Lash A., Bowler R.M., Shore M., Becker C.E.
Título Neuropsychologic "impairment" in a cohort of hospital workers chronically exposed to ethylene oxide
Información bibliográfica 1990, Vol.28, No.1, p.21-28. 9 ref.
Resumen Ethylene oxide is widely used to sterilise heat-sensitive materials. Acute and chronic neurogenic effects to the central and peripheral nervous system in man and animals have been described. A cross-sectional study of 25 hospital central sypply workers exposed to low levels of ethylene oxide and 24 unexposed control workers was conducted. Subjects were tested with a neuropsychological screening battery by examiners blinded to exposure status. Results were reviewed independently by 2 neuropsychologists without knowledge of exposure. Subject status was categorized as normal, "impaired," or disagreement (between the two neuropsychologists). There were more subjects concordantly judged as impaired in the exposed group than in the control group. Although limited by the cross-sectional study design and the global categorisation, these findings suggest that central nervous system dysfunction and cognitive impairment may result from chronic ethylene oxide exposure in hospital central sypply units.
Descriptores (primarios) desinfección del material; enfermedades del sistema nervioso; efectos neuropsíquicos; hospitales; óxido de etileno
Descriptores (secundarios) exposición de larga duración; rendimiento cognitivo
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaEstados Unidos
Tema(s) Cemercio, servicios, oficinas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Diseases of the nervous system
Ethers
Ethylene oxide
Health care services