| ID (ISN) del documento | 55097 |
| Número CIS |
90-1985 |
| Año |
1989 |
| Número de serie |
HSE Specialist Inspector Reports No.21
|
| Autor(es) |
Turner R.M., Fairhurst S. |
| Título |
Assessment of the toxicity of major hazard substances |
| Información bibliográfica |
Health and Safety Executive, Library and Information Services, Broad Lane, Sheffield S3 7HQ, United Kingdom, May 1989. 13p. 32 ref. |
| Resumen |
This paper proposes a systematic approach for expressing the toxicological hazard to human health posed by the airborne release of a major hazard substance. The importance of using reliable toxicity data from original sources is discussed. Criteria defining the level of toxicity on which risk calculations are based are described in terms of individual risk, i.e. the likelihood of an individual receiving an exposure which will produce a specified level of toxicity, and societal risk, the frequency of a given number of deaths from a specific cause. A method is described for deriving the relationship between the atmospheric concentration of the substance and the duration of exposure for a given level of toxicity. The parameters thus deemed may be used in major hazard risk analysis. |
| Descriptores (primarios) |
toxicología; riesgos químicos; grandes riesgos; valoración del riesgo |
| Descriptores (secundarios) |
efectos tóxicos; informe; análisis matemático; extrapolación del animal al hombre; duración de la exposición; concentración letal 50 |
| Tipo de documento |
E - Libros, informes, actas |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Major hazards
Risk evaluation
|
