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Base de datos CISDOC

ID (ISN) del documento54983
Número CIS 90-1977
ISBN(s) 87-7303-431-2; 91-7996-222-X
Año 1990
Número de serie KEMI Report 2/90
Autor(es)
Nordic Council of Ministers
Título Effects on reproduction of styrene, toluene and xylene
Información bibliográfica Swedish National Chemicals Inspectorate, Information Secretariat, P.O. Box 1484, 171 27 Solna, Sweden, 1990. 77p. 39 ref. Price: SEK 80.00.
Resumen Exposure to styrene is reported to cause an increase in spontaneous abortion and an increased frequency of structural chromosomal abnormalities in adults. There is currently insufficient evidence to determine the carcinogenicity of styrene, although styrene oxide is probably carcinogenic. Toluene sniffing during pregnancy is reported to cause malformation of the foetus at high concentrations. At low concentrations, toluene is a reproductive toxicant affecting the hormone balance in adults and development of the foetus. Human data suggest that exposure to solvents during pregnancy may cause congenital malformations and spontaneous abortions, although no firm conclusions on the contribution of xylene can be made.
Descriptores (primarios) efectos esterilizantes; Suecia; xileno; estireno; toxicología; tolueno
Descriptores (secundarios) efectos mutágenos; efectos tóxicos; efectos embriotóxicos; óxido de estireno; disolvente; documentación de base; trastornos de la espermatogénesis; trastornos menstruales; investigaciones en el animal; embarazadas; efectos cancerígenos; aborto
Tipo de documento E - Libros, informes, actas
País / Estado o ProvinciaSuecia
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Antifertility and prenatal effects
Aromatic hydrocarbons
Genetic factors in reaction to exposures