ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento53788
Número CIS 90-804
ISSN - Título de la serie 0271-3586 - American Journal of Industrial Medicine
Año 1989
Número de serie
Autor(es) Thrasher J.D., Madison R., Broughton A., Gard Z.
Título Building-related illness and antibodies to albumin conjugates of formaldehyde, toluene diisocyanate, and trimellitic anhydride
Información bibliográfica 1989, Vol.15, No.2, p.187-195. Bibl.
Resumen A case of building-related health complaints was investigated with respect to the relationship among frequency of symptoms, antibodies to albumin conjugates of formaldehyde (HCHO), toluene diisocyanate (TDI), and trimellitic anhydride (TMA), and volatile organic chemicals (VOCs). The indoor air concentrations of VOCs, HCHO, TDI and TMA did not exceed Fed-OSHA and ACGIH permissible standards. However, HCHO concentrations ranged between 0.05 and 0.08ppm. The reported symptoms were multiple, involving the eyes, nose, sinuses, throat, lungs, skeletomuscular system and central nervous system. Anti-HCHO, TDI, and TMA isotypes were found in 12 of 14 full-time employees and were nondetectable in one part-time employee. The data suggest that a synergistic immunological response to airborne chemicals may be occurring in these subjects. In conclusion, immunological monitoring of affected individuals where chemicals are suspected may prove to be useful in future investigations of building-related illness.
Descriptores (primarios) formaldehido; compuestos orgánicos; diisocianato de toluileno; enfermedades de los edificios; substancias volátiles; anhídrido trimelítico; modificaciones inmunobiológicas; síntomas
Descriptores (secundarios) límites admisibles; tests de exposición; dosimetría individual
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s) Aspectos generales
Navegación por categoria(s) Sick building syndrome
Isocyanates
Cyano compounds
Aldehydes