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Base de datos CISDOC

ID (ISN) del documento51720
Número CIS 89-920
ISSN - Título de la serie 0301-0023 - Journal of the Society of Occupational Medicine
Año 1988
Número de serie
Autor(es) Chattopadhyay P., Karnik A.B., Thakore K.N., Lakkad B.C., Nigam S.K., Kashyap S.K.
Título Health effects among workers involved in the manufacture of hexachlorocyclohexane
Información bibliográfica Autumn 1988, Vol.38, No.3, p.77-81. Illus. 17 ref.
Resumen Forty-five male workers exposed to hexachlorocyclohexane (HCH) during its manufacture were studied and compared with 22 matched controls. Twenty-one of the exposed workers worked in packaging and manual transport of HCH. Twenty-four other exposed workers were plant operators. Exposure was mainly through skin. Results indicate that the neurological symptoms reported were due to recent exposure to HCH and were related to the intensity of exposure. An increase in leucine aminopeptidase, ornithine carbamyl transaminase, 5'nucleotides and immunoglobulin M levels among the exposed workers is suggestive of some degree of liver damage. A significant increase in total blood HCH and its α, β and γ isomers was also observed in these workers. In spite of pronounced exposure to the α, β and γ isomers of HCH, signs of severe health impairment were not observed. Further biological monitoring needs to be carried out among such workers exposed to HCH.
Descriptores (primarios) productos químicos agrarios; hexaclorociclohexano; agricultura; valoración de la exposición; pesticidas
Descriptores (secundarios) India; empaquetado y rellenado; efectos hepatotóxicos; absorción cutánea; substancias tóxicas; estudio comparado; efectos neurológicos; intoxicaciones crónicas; duración de la exposición; exámenes médicos; paises en desarrollo; edad
Tipo de documento D - Artículos periódicos
Tema(s) Agricultura, pesca, cría de ganado
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Exposure evaluation
Halogenated hydrocarbons
Agricultura
Agricultural chemicals