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Base de datos CISDOC

ID (ISN) del documento46115
Número CIS 86-1002
Año 1985
Número de serie Environmental Health Criteria 56
Título Propylene Oxide
Información bibliográfica World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1985. 53p. 99 ref. Price: SF.8.00.
Resumen Exposure of man to propylene oxide mainly occurs through inhalation at the workplace. Taking into account the body of available data - the alkylating nature of propylene oxide, the formation of DNA adducts, the positive response in in vitro mutagenesis assays, the carcinogenic effects in animals at the sites of entry into the body, and the absence of adequate data on cancer in human beings - propylene oxide should be regarded as if it presented a carcinogenic risk for man, and levels in the environment should be kept as low as feasible.
Descriptores (primarios) toxicología; valoración del riesgo; óxido de propileno
Descriptores (secundarios) efectos mutágenos; efectos cancerígenos; investigaciones en el animal
Tipo de documento E - Libros, informes, actas
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Ethylene oxide
Genetic factors in reaction to exposures
Risk evaluation
Ethers