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Base de datos CISDOC

ID (ISN) del documento43459
Número CIS 85-498
ISSN - Título de la serie 0098-7484 - Journal of the American Medical Association
Año 1984
Número de serie
Autor(es) Suskind R.R., Hertzberg V.S.
Título Human health effects of 2,4,5-T and its toxic contaminants
Información bibliográfica 11 May 1984, Vol.251, No.18, p.2372-2380. 42 ref.
Resumen A clinical epidemiological study was conducted on a population consisting of 204 white males exposed to the herbicide 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) and contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin, as a result of employment in the production of 2,4,5-T between 1948 and 1969, and 163 white males currently or formerly employed at the same plant but never associated with production or maintenance functions. In the exposed group clinical evidence of chloracne persisted in 55.7%, but none was found among unexposed workers. Persistence of chloracne was also associated with the presence and severity of actinic elastosis of the skin. An association was found between exposure and the history of gastrointestinal tract ulcer. Among smokers, pulmonary function values were lower among exposed workers than among unexposed workers. An evidence was found of increased risk for cardiovascular disease, hepatic disease, renal damage or central or peripheral nervous system problems.
Descriptores (primarios) herbicidas; ácido triclorofenoxiacético; efectos biológicos; acné clórico; úlcera gástrica
Descriptores (secundarios) tetraclorodibenzodioxina; fumadores; afectación respiratoria; exposición de larga duración; encuesta epidemiológica
Tipo de documento D - Artículos periódicos
Tema(s) Agricultura, pesca, cría de ganado
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Skin diseases
Gastrointestinal diseases