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Base de datos CISDOC

ID (ISN) del documento41899
Número CIS 84-838
ISSN - Título de la serie 0025-729X - Medical Journal of Australia
Año 1983
Número de serie
Autor(es) Pearn J.H.
Título Teratogens and the male - An analysis with special reference to herbicide exposure
Información bibliográfica 9 July 1983, Vol.2, No.1, p.16-20. 44 ref.
Resumen There are 3 mechanisms by which exposure of the male to toxic substances may cause poor reproductive performance or congenital malformations in his offspring: a direct effect on pituitary-hypothalamic function or male sex hormones; a direct effect on the sperm itself; abnormalities in seminal fluid with secondary abnormalities due to dissolved toxins. Experimental studies with 7 drugs and 5 groups of toxic chemicals are reviewed. Clinical studies reviewed relate to lead, vinyl chloride, the insecticide carbaryl, the pesticides chlordecone and dibromochloropropane, radiation, fathers with epilepsy, and male and female anaesthetists.
Descriptores (primarios) herbicidas; diferencias por el sexo; efectos genéticos; substancias teratogénicas
Descriptores (secundarios) radiación ionizante; cambio de horizontes; bifenilos policlorados; cepona; plomo; ácido diclorofenoxiacético; ácido triclorofenoxiacético; tetraclorodibenzodioxina; anestésicos por inhalación; epilepsia; pesticidas; insecticidas; negamón; carbaril; talidomida; cloruro de vinilo
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Genetic factors in reaction to exposures
Antifertility and prenatal effects