| ID (ISN) del documento | 41467 |
| Número CIS |
84-487 |
| ISSN - Título de la serie |
0098-4108 - Journal of Toxicology and Environmental Health |
| Año |
1982 |
| Número de serie |
|
| Autor(es) |
Cushman J.R., Street J.C. |
| Título |
Allergic hypersensitivity to the herbicide 2,4-D in BALB/c mice |
| Información bibliográfica |
Oct.-Nov. 1982, Vol.10, Nos.4-5, p.729-741. Illus. 35 ref. |
| Resumen |
Following several reports of human allergic hypersensitivity, the ability of 2,4-dichlorophenoxyacetic acid (2,4-D) to elicit 2,4-D-specific IgE antibodies and delayed-type hypersensitivity in mice was studied. Following the second intraperitoneal immunisation with 1, 10 or 100µg of a 2,4-D conjugate, 2,4-D-specific IgE antibodies were detected in mouse sera. The highest antibody titers and a measurable response in all mice were seen in the group that received 1µg of 2,4-D conjugate. 2,4-D applied epicutaneously on 2 days or over 4 weeks failed to elicit delayed-type hypersensitivity, and no 2,4-D-specific IgE antibodies were detected in serum. |
| Descriptores (primarios) |
herbicidas; inmunología; alergias; ácido diclorofenoxiacético |
| Descriptores (secundarios) |
alteraciones de las inmunoglobulinas; investigaciones en el animal; protección de los cultivos |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Alergias
Agricultural chemicals
|
