ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento40723
Número CIS 83-1961
ISSN - Título de la serie 0038-5077 - Sovetskaja medicina
Año 1982
Número de serie
Autor(es) Polonskaja V.V., Drozdova G.A., Misautova A.A., Odinokova V.A., Ljubčenko P.N.
Título Functional and morphological features of the mucosa of the small intestine in victims of chronic lead poisoning
Título original Funkcional'no-morfologičeskie osobennosti slizistoj oboločki tonkoj kiški u bol'nyh s hroničeskoj svincovoj intoksikaciej [en ruso]
Información bibliográfica 1982, No.1, p.24-29. 31 ref.
Resumen The morphology and γ-amylase and alkaline phosphatase activities of the mucosa of the proximal small intestine were examined in 40 workers who had had prolonged contact with lead; 26 showed symptoms of chronic lead poisoning while 14 were asymptomatic. Both asymptomatic and symptomatic groups showed reduced levels of both enzymes in comparison with unexposed controls. Alkaline phosphatase activity in intestinal juice was also reduced. Both lead-exposed groups also showed dystrophic changes in the enterocytes and villi of the mucosa and a reduced number of caliciform cells. Morphological alterations in the blood vessels suggested altered microcirculation in both groups. There was no quantitative difference between symptomatic and asymptomatic groups. The observed physiological effects of lead may contribute to the "abdominal syndrome" observed in lead poisoning, and should be taken into account in the diet of lead poisoning victims.
Descriptores (primarios) trastornos circulatorios; enfermedades del intestino; alteraciones enzimáticas; plomo
Descriptores (secundarios) glucoamilasa; cólicos; fosfatasas alcalinas
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Inorganic substances
Lead and compounds
Gastrointestinal diseases
Cardiovascular diseases
Blood diseases