| ID (ISN) del documento | 39932 |
| Número CIS |
83-1006 |
| ISSN - Título de la serie |
0047-1879 - Japanese Journal of Industrial Health - Sangyō-Igaku |
| Año |
1982 |
| Número de serie |
|
| Autor(es) |
Katahira T., Teramoto K., Horiguchi S. |
| Título |
Experimental studies on the acute toxicity of tetrahydrofuran in animals |
| Información bibliográfica |
1982, Vol.24, No.4, p.373-378. Illus. 35 ref. |
| Resumen |
20% tetrahydrofuran (THF) in various doses was given intraperitoneally and by inhalation to rats and mice. The intraperitoneal LD50 was 1,900-2,900mg/kg according to the solvent and animal used. LC50 was 21,000ppm when inhaled for 3h by rats. There were no significant effects of 100-200ppm THF for 3h in rats except for slight local irritant symptoms. Irritant and central nervous system symptoms occurred with inhalation of 5,000ppm THF. |
| Descriptores (primarios) |
tetrahidrofurano; disolventes orgánicos; toxicidad aguda |
| Descriptores (secundarios) |
investigaciones en el animal; concentración letal 50; dosis letal 50 |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Heterocyclic compounds
|
