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Base de datos CISDOC

ID (ISN) del documento38919
Número CIS 83-152
ISSN - Título de la serie 0007-1072 - British Journal of Industrial Medicine
Año 1982
Número de serie
Autor(es) Karai I., Fukumoto K., Horiguchi S.
Título Mechanism of increased osmotic resistance of red cells in workers exposed to lead
Información bibliográfica May 1982, Vol.39, No.2, p.153-156. Illus. 17 ref.
Resumen The mechanism of increased osmotic resistance in red blood cells in lead workers was studied by examining 19 lead refining workers and 18 controls for red cell count, haematocrit, mean corpuscular volume, blood and urine lead concentrations, urine coproporphyrin and delta-aminolaevulinic acid (DALA), osmotic resistance of red cells, lecithin-cholesterol acyltransferase (LCAT) activity in serum, and cholesterol content and cholesterol-to-phospholipid ratio of the red cell membrane. Osmotic resistance of red cells, red cell membrane cholesterol content, blood and urine lead, urine coproporphyrin and urine DALA were higher in lead workers than in controls. In lead workers, close correlations were found between osmotic resistance and blood lead concentration, osmotic resistance, LCAT activity and red cell membrane cholesterol.
Descriptores (primarios) plomo; eritrocitos; industria del plomo; fragilidad globular
Descriptores (secundarios) recuento de glóbulos y plaquetas; vigilancia del ALA en orina; relación dosis-respuesta; estudio comparado; vigilancia de la orina; determinación de la actividad enzimática; citología sanguínea; vigilancia de la sangre
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Blood diseases
Smelting and refining operations
Lead and compounds
Inorganic substances