| ID (ISN) del documento | 38675 |
| Número CIS |
82-1956 |
| ISSN - Título de la serie |
0007-1072 - British Journal of Industrial Medicine |
| Año |
1981 |
| Número de serie |
|
| Autor(es) |
Alessio L., Castoldi M.R., Odone P., Franchini I. |
| Título |
Behaviour of indicators of exposure and effect after cessation of occupational exposure to lead |
| Información bibliográfica |
Aug. 1981, Vol.38, No.3, p.262-267. Illus. 17 ref. |
| Resumen |
The behaviour of blood lead (PbB) and some biological markers of lead incorporation (erythrocyte protoporphyrin IX (EP), delta-aminolaevulinic acid dehydratase (ALAD) and urinary delta-aminolaevulinic acid (ALAU)) were studied in subjects who had ceased working with inorganic lead for at least 1 year. Relations were analysed between these indices and lead deposits in the body as determined by chelatable lead (PbU-EDTA) in urine following intravenous injection of 1g CaNa2EDTA and compared with findings in workers currently exposed to lead. In workers with ceased exposure, PbB levels were significantly lower, EP levels were identical for corresponding levels of chelatable lead but lower in relation to PbB levels and ALAU levels were distinctly lower at the same PbU-EDTA levels but identical for similar PbB levels. It is concluded that in subjects with past exposure, EP and ALAD can be used to determine persistence and extent of an "active deposit" of lead in the body but that PbB is of very limited use. |
| Descriptores (primarios) |
plomo; vigilancia del ALA en orina; retención en el organismo; vigilancia de la sangre; tests de exposición |
| Descriptores (secundarios) |
ALAD; estudio comparado; dosificación de las porfirinas libres; movilización por quelantes |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Inorganic substances
Biological monitoring
Lead and compounds
|
