ID (ISN) del documento | 38517 |
Número CIS |
82-1696 |
ISSN - Título de la serie |
0340-0131 - International Archives of Occupational and Environmental Health |
Año |
1981 |
Número de serie |
|
Autor(es) |
Triebig G., Krekeler H., Golssler K., Valentin H. |
Título |
Investigations on neurotoxicity of chemical substances at the wprkplace - II. Determination of the motor and sensory nerve conduction velocity in persons occupationally exposed to pentachlorophenol |
Título original |
Untersuchungen zur Neurotoxizität von Arbeitsstoffen - II. Messung der motorischen und sensorischen Nervenleitgeschwindigkeit bei beruflich Pentachlorophenol-belasteten Personen [en alemán] |
Información bibliográfica |
1981, Vol.48, No.4, p.357-367. 22 ref. |
Resumen |
Methods and results of examinations of 18 workers with a mean activity of 12 years in processing pentachlorophenol (PCP). The PCP levels in plasma ranged between 0.02 and 1.5ng/l (median 0.25ng/l) and in urine between 13 and 1.224µg/l (median 112γ/l) or between 11 and 2.111µg/l creatinine (median 111µg/g). The median values of the neurophysiological parameters showed a slight slowing trend, The decrease in sensory nerve conduction velocities was significant. A dose-effect relation between internal PCP load and nerve conduction velocities could not be demonstrated. The individual evaluation of the toxicological and neurophysiological results suggested that in some cases decreased nerve conduction velocity is caused by chronic exposure to PCP. |
Descriptores (primarios) |
efectos neurotóxicos; pentaclorofenol; producción de pesticidas; conducción nerviosa; pesticidas |
Descriptores (secundarios) |
velocidad de conducción; conductividad de las fibras motoras |
Tipo de documento |
D - Artículos periódicos |
Tema(s) |
Patología profesional
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Broad subject area(s) |
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Navegación por categoria(s) |
Agricultural chemicals Chemical industry Diseases of the nervous system Phenols and phenolic compounds Alcohols
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