| ID (ISN) del documento | 38453 |
| Número CIS |
82-1677 |
| ISSN - Título de la serie |
0019-8366 - Industrial Health |
| Año |
1982 |
| Número de serie |
|
| Autor(es) |
Nomiyama K., Nomiyama H., Yotoriyama M. |
| Título |
Low-molecular-weight proteins in urine from rabbits given nephrotoxic compounds |
| Información bibliográfica |
1982, Vol.20, No.1, p.1-10. Illus. 25 ref. |
| Resumen |
Rabbits were given 0.5mg cadmium (Cd)/kg by subcutaneous injection 6 times a week for 32 weeks. The main protein component in the urine of these animals had a molecular weight (MW) of ≥67,000 suggesting tubular and glomerular dysfunction. Low MW proteins were found, in addition, in the urine of animals given a single injection of uranium (U), chromium (Cr), or mercury (Hg). The MW distribution of proteins in the urine of these animals was very similar to that of Cd-treated rabbits. Low MW tubular reabsorption of phosphorus was >80%. |
| Descriptores (primarios) |
mercurio; uranio; toxicología; cromo; efectos nefrotóxicos; cadmio; proteinuria |
| Descriptores (secundarios) |
investigaciones en el animal; disfunción renal |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Inorganic substances
Diseases of the kidney and the urinary system
Mercury and compounds
Cadmium and compounds
|
