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Base de datos CISDOC

ID (ISN) del documento38405
Número CIS 82-1547
ISSN - Título de la serie 0098-4108 - Journal of Toxicology and Environmental Health
Año 1982
Número de serie
Autor(es) Castranova V., Bowman L., Shreve J.M., Jones G.S., Miles P.R.
Título Volcanic ash: toxicity to isolated lung cells
Información bibliográfica Feb. 1982, Vol.9, No.2, p.317-325. Illus. 24 ref.
Resumen The toxicity of ash from the Mount St. Helens eruption, of 18 May 1980, was estimated by monitoring the effects of in-vitro and in-vivo exposure on various physiological parameters of lung cells. The ash had little effect on oxygen consumption of rabbit type II pneumocytes, oxygen consumption or superoxide release of resting rat alveolar macrophages, or membrane integrity of rat alveolar macrophages. No significant lipid peroxidation in lung microsomes was found. The ash did inhibit superoxide anion release from zymosan-stimulated macrophages and may adversely affect the ability of these to protect the lung from infection. The findings are significant for workers exposed to ash during reclamation or logging of affected areas.
Descriptores (primarios) efectos tóxicos; vulcanismo; cenizas; polvos respirables; depósito en los pulmones
Descriptores (secundarios) macrófagos; anomalías globulares; inmunología; valoración de la exposición; bioquímica pulmonar
Tipo de documento D - Artículos periódicos
Tema(s) Polvos, aerosoles
Broad subject area(s)
Navegación por categoria(s) Natural phenomena