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Base de datos CISDOC

ID (ISN) del documento36747
Número CIS 81-2015
ISSN - Título de la serie 0004-1254 - Arhiv za higijenu rada i toksikologiju
Año 1981
Número de serie
Autor(es) Horvat Dj., Račić J., Rozgaj R.
Título Frequency of sister chromatid exchanges in V79 cells of Chinese hamsters exposed to heavy metals
Título original Učestalost izmjena kromatida sestara u V79 stanica kineskog hrčka nakon izloženosti teškim metalima [en serbocroata]
Información bibliográfica 1981, Vol.32, No.2, p.147-156. Illus. 26 ref.
Resumen The sister chromatid exchange (SCE) method was used to investigate the mutagenic effect of heavy metals (Pb++, MN++, Ni++, Cd++). In vitro experiments with Chinese hamster V79 cells showed that Pb and Ni did not cause any significant change in SCE values, whereas exposure to Mn and Cd increased the number of changes; in particular, Cd had a marked mutagenic effect, doubling the number of exchanges after 2-h cell incubation.
Descriptores (primarios) manganeso; níquel; cadmio; cambios cromosómicos; efectos citotóxicos; plomo
Descriptores (secundarios) pruebas in vitro
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Nickel and compounds
Cadmium and compounds
Lead and compounds
Inorganic substances