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Base de datos CISDOC

ID (ISN) del documento36607
Número CIS 81-1996
ISSN - Título de la serie 0003-9896 - Archives of Environmental Health
Año 1980
Número de serie
Autor(es) Forni A., Sciamè A., Bertazzi P.A., Alessio L.
Título Chromosome and biochemical studies in women occupationally exposed to lead
Información bibliográfica May-June 1980, Vol.35, No.3, p.139-145. 13 ref.
Resumen Blood lead levels and erythrocyte protoporphyrin and δ-aminolevulinic acid dehydratase activity of red blood cells were determined for 18 healthy females occupationally exposed to lead in the manufacture of electrical storage batteries and 12 female controls. Cytogenetic studies were performed on lymphocytes cultured for 2 and 3 days with phytohaemagglutinin. Significantly increased rates of metaphases with chromatid and chromosome aberrations, excluding gaps, were observed in the exposed vs. the control group at both culture times. The yield of abnormal metaphases was higher in the 3-day than in the 2-day cultures, in both exposed and control groups, but the difference was only moderately significant for controls and highly significant for those exposed. These results are consistent with those found for males.
Descriptores (primarios) plomo; efectos bioquímicos; mujeres; fabricación de pilas y acumuladores; cambios cromosómicos
Descriptores (secundarios) estudio comparado; análisis de las aberraciones cromosómicas
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Manufacturing of electrical appliances and equipment
Lead and compounds
Inorganic substances