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ID (ISN) del documento36461
Número CIS 81-1678
ISSN - Título de la serie 0019-8366 - Industrial Health
Año 1981
Número de serie
Autor(es) Mithal R.K.
Título Histopathological studies with reference to chronic cadmium exposure in adrenal and spleen of common Indian ground squirrel
Información bibliográfica 1981, Vol.19, No.1, p.9-14. Illus. 8 ref.
Resumen Ground squirrels were injected intraperitoneally with a daily dose of cadmium acetate, at 1.0mg Cd/kg body weight, for 4, 5, 6 and 7 weeks, and the adrenals and spleen of exposed animals were compared with those of controls. The adrenals showed dilatation of sinusoids, fatty change in the cells of the cortex, hyaline-like mass in the medulla, haemorrhage adjacent to the medulla, circumscribed haemorrhage in the cortex, and congested blood vessels. The spleen showed congestion in blood vessels, thickening of vessel walls, and congestion and dilatation of sinusoids. The body weight gain of Cd-exposed animals was significantly lower than that of the controls, and the increase in spleen weight was significantly higher.
Descriptores (primarios) esplenopatias; cadmio; histopatología; trastornos suprarrenales
Descriptores (secundarios) bazo; acetato de cadmio; peso corporal; exposición de larga duración; toxicidad crónica; investigaciones en el animal
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Inorganic substances
Endocrine diseases
Blood diseases
Cadmium and compounds