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Base de datos CISDOC

ID (ISN) del documento33222
Número CIS 80-763
ISSN - Título de la serie 0340-0131 - International Archives of Occupational and Environmental Health
Año 1979
Número de serie
Autor(es) Veulemans H., Van Vlem E., Janssens H., Masschelein R.
Título Exposure to toluene and urinary hippuric acid excretion in a group of heliorotogravure printing workers.
Información bibliográfica Sep. 1979, Vol.44, No.2, p.99-107. Illus. 12 ref.
Resumen The influence of a number of factors possibly affecting the relation between urinary hippuric acid excretion and the exposure level to toluene was studied in rotogravure printers. After 4h and 8h from the onset of exposure, the hippuric acid excretion rates (mg/min) were in better agreement with the average toluene air concentrations than either the urinary metabolite concentrations (mg/l) alone or corrected for urine density. Apart from differences in exposure level, a substantial proportion of the interindividual variability in hippuric acid excretion could be explained by differences in work load (and consequently in lung clearance for toluene) during exposure. Skin absorption of toluene is probably another factor influencing metabolite excretion. In agreement with previous findings, the hippuric acid excretion rate apparently does not depend on the time of urine sampling during exposure, provided that at least 4h have elapsed from the onset.
Descriptores (primarios) imprenta; tolueno; vigilancia de la orina; tests de exposición; metabolitos urinarios
Descriptores (secundarios) ácido hipúrico; heliograbado; relación dosis-respuesta
Tipo de documento -
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Biological monitoring
Aromatic hydrocarbons
Printing, photography and photocopying industry