ID (ISN) del documento | 32926 |
Número CIS |
80-371 |
ISSN - Título de la serie |
0036-8075 - Science |
Año |
1979 |
Número de serie |
|
Autor(es) |
Liebeskind D., Bases R., Mendez F., Elequin F., Koenigsberg M. |
Título |
Sister chromatid exchanges in human lymphocytes after exposure to diagnostic ultrasound. |
Información bibliográfica |
21 Sep. 1979, Vol.205, p.1273-1275. 19 ref. |
Resumen |
Report on the effects of ultrasound on the incidence of sister chromatid exchanges (SCE), a sensitive direct indicator of chromosome damage. Exposure to diagnostic levels of ultrasound increased the frequency of SCE in freshly isolated human lymphocytes as well as in a continuously growing human lymphoblast line. The in-vitro methods of blood treatment, staining and exposure to ultrasound (30min, 700 pulses per second) are described. Temporal average intensity is estimated to be as high as 5.0mW/cm2. The mechanism of SCE and the relationship between SCE frequency and mutagenic potential are discussed. The results confirm previous findings indicating that ultrasound can affect the DNA of animal cells, and suggest that ultrasound may not be entirely innocuous. |
Descriptores (primarios) |
ultrasonido; efectos extrauditivos; cambios cromosómicos |
Descriptores (secundarios) |
efectos mutágenos; estudio comparado; pruebas in vitro |
Tipo de documento |
- |
Tema(s) |
Ruido, audición, vibraciones
|
Broad subject area(s) |
|
Navegación por categoria(s) |
Antifertility and prenatal effects Noise Genetic factors in reaction to exposures
|