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Base de datos CISDOC

ID (ISN) del documento31783
Número CIS 79-1345
ISSN - Título de la serie 0009-9309 - Clinical Toxicology
Año 1978
Número de serie
Autor(es) Reuber M.D.
Título Carcinomas and other lesions of the liver in mice ingesting organochlorine pesticides.
Información bibliográfica Sep. 1978, Vol.13, No.2, p.231-256. Illus. 78 ref.
Resumen Carcinomas of the liver were readily induced in male and female mice given organochlorine pesticides by mouth. The carcinomas were predominantly hepatocellular, a few being cholangiocellular, and varied from well differentiated to poorly differentiated and undifferentiated. They are capable of invading, metastasing, and killing the mice. Haemangiosarcomas, leiomyosarcomas and reticulum cell sarcomas were also occasionally seen. Hepatic vein thrombosis and hepatic necrosis occurred in some mice.
Descriptores (primarios) efectos hepatotóxicos; hidrocarburos clorados; cáncer de hígado; pesticidas
Descriptores (secundarios) lesiones hepáticas; metoxicloro; aldrin; dieldrin; endrin; clordano; heptacloro; epóxido de heptacloro; cepona; mirex; lindano; clorobencilato; ingestión; investigaciones en el animal; DDT
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Halogenated hydrocarbons
Agricultural chemicals