| ID (ISN) del documento | 29293 |
| Número CIS |
78-774 |
| ISSN - Título de la serie |
1775-8785 - Archives des maladies professionnelles |
| Año |
1977 |
| Número de serie |
|
| Autor(es) |
Conso F., Neel P., Pouzoulet C., Efthymiou M.L., Gervais P., Gaultier M. |
| Título |
Acute poisoning by halogenated hydroxybenzonitrile derivatives in man (ioxynil, bromoxynil). |
| Título original |
Toxicité aiguë chez l'homme des dérivés halogénés de l'hydroxybenzonitrile (ioxynil, bromoxynil) [en francés] |
| Información bibliográfica |
July-Aug. 1977, Vol.38, No.7-8, p.674-677. |
| Resumen |
Description of 4 cases of acute poisoning in workers at the drying stage in the production process for these herbicides. The biochemical action of 3,5-dibromo-4-hydroxybenzonitrile or bromoxynil, and 3,5,-diiodo-4-hydroxybenzonitrile or ioxynil is the same as that of 2,4-dinitrophenol and dinitro-o-cresol: disturbance of the cellular oxidative phosphorylation processes, giving rise to pathological sweating followed by thirst, emaciation and functional renal insufficiency. Poisoning was due in a large measure to a considerable increase in production without a parallel increase in the ventilation capacity of the workshop. Factors favouring poisoning: heat, long working hours, neglect of hygiene rules (shower after work, wearing of mask). |
| Descriptores (primarios) |
herbicidas; envenenamiento agudo; producción de pesticidas; yoxinil; bromooxinilo |
| Descriptores (secundarios) |
estudio de caso; efectos citotóxicos; efectos bioquímicos; insuficiencia renal |
| Tipo de documento |
- |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Agricultural chemicals
Cyano compounds
Chemical industry
|
