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Base de datos CISDOC

ID (ISN) del documento29249
Número CIS 78-801
ISSN - Título de la serie 0028-4793 - New England Journal of Medicine
Año 1978
Número de serie
Autor(es) Cohn W.J., Boylan J.J., Blanke R.V., Fariss M.W., Howell J.R., Guzelian P.S.
Título Treatment of chlordecone (Kepone) toxicity with cholestyramine - Results of a controlled clinical trial.
Información bibliográfica 2 Feb. 1978, Vol.298, No.5, p.243-248. 24 ref.
Resumen Cholestyramine is an anion-exchange resin that binds chlordecone. It was given for 5 months to 12 workers who had been exposed to chlordecone during manufacture, while 10 received a placebo. The toxicity and modes of elimination of chlordecone before and after therapy are reported. Cholestyramine significantly accelerated elimination of chlordecone from blood and fat. The treatment offers a practical means of detoxifying persons exposed to this and possibly other lipophilic toxins.
Descriptores (primarios) cepona; pesticidas; quimioterapia; intoxicaciones crónicas; colestiramina
Descriptores (secundarios) cambiantes de iones; relación dosis-respuesta; excreción fecal
Tipo de documento -
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Halogenated hydrocarbons
Agricultural chemicals