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Base de datos CISDOC

ID (ISN) del documento25915
Número CIS 76-1665
ISSN - Título de la serie 0323-9179 - Problemi na higienata
Año 1975
Número de serie
Autor(es) Hinkova L., Kalojanova F., Dimov S., Acev E.
Título Comparative study of EEG and cholinesterase activity changes in experimental intoxication with dipterex
Título original Sravnitelno izsledvane na promenite v EEG i holinesteraznata aktivnost pri eksperimentalna intoksikacija s diptereks [en búlgaro]
Información bibliográfica 1975, Vol.1, No.1, p.39-44. Illus. 2 ref.
Resumen Dipterex (chlorophos) administered intraperitoneally (3 and 6mg/kg) and intramuscularly (10 and 20mg/kg) in cats inhibited cholinesterase activity in all the experiments, while EEG changes were mild and irregular. Desynchronisation of the spontaneous EEG prevailed after a single dose of dipterex; on activation by photic stimulation, on the other hand, an increase in late negative potentials was predominant. Repeated administration of dipterex gave rise to theta rhythms and activation of pre-existing seizure patterns. Discussion of the correlation between EEG changes and cholinesterase activity.
Descriptores (primarios) colinesterasa; alteraciones enzimáticas; clorofós; alteraciones electroencefalográficas; insecticidas
Descriptores (secundarios) efectos neurotóxicos; estudio comparado; investigaciones en el animal; compuestos organofosforados
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Mental health
Blood diseases
Esters and salts