ID (ISN) del documento | 25915 |
Número CIS |
76-1665 |
ISSN - Título de la serie |
0323-9179 - Problemi na higienata |
Año |
1975 |
Número de serie |
|
Autor(es) |
Hinkova L., Kalojanova F., Dimov S., Acev E. |
Título |
Comparative study of EEG and cholinesterase activity changes in experimental intoxication with dipterex |
Título original |
Sravnitelno izsledvane na promenite v EEG i holinesteraznata aktivnost pri eksperimentalna intoksikacija s diptereks [en búlgaro] |
Información bibliográfica |
1975, Vol.1, No.1, p.39-44. Illus. 2 ref. |
Resumen |
Dipterex (chlorophos) administered intraperitoneally (3 and 6mg/kg) and intramuscularly (10 and 20mg/kg) in cats inhibited cholinesterase activity in all the experiments, while EEG changes were mild and irregular. Desynchronisation of the spontaneous EEG prevailed after a single dose of dipterex; on activation by photic stimulation, on the other hand, an increase in late negative potentials was predominant. Repeated administration of dipterex gave rise to theta rhythms and activation of pre-existing seizure patterns. Discussion of the correlation between EEG changes and cholinesterase activity. |
Descriptores (primarios) |
colinesterasa; alteraciones enzimáticas; clorofós; alteraciones electroencefalográficas; insecticidas |
Descriptores (secundarios) |
efectos neurotóxicos; estudio comparado; investigaciones en el animal; compuestos organofosforados |
Tipo de documento |
- |
Tema(s) |
Sustancias tóxicas y peligrosas
|
Broad subject area(s) |
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Navegación por categoria(s) |
Blood diseases Esters and salts Agricultural chemicals Mental health
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