| ID (ISN) del documento | 25723 |
| Número CIS |
76-1616 |
| ISSN - Título de la serie |
0095-6562 - Aviation, Space, and Environmental Medicine |
| Año |
1976 |
| Número de serie |
|
| Autor(es) |
Revzin A.M. |
| Título |
Effects of organophosphate pesticides and other drugs on subcortical mechanisms of visual integration. |
| Información bibliográfica |
June 1976, Vol.47, No.6, p.627-629. Illus. 10 ref. |
| Resumen |
Atropine, scopolamine, mevinphos, and eserine selectively block directional sensitivity of visual integrative neurones in the thalamus. Cholinergic drugs that do not penetrate the blood-brain barrier are without effect. The neurones studied are important links in reflex brain systems controlling visual attention and eye movements. The results suggest that any cholinergic drug that can reach the brain will disturb visual functions. Since the changes are qualitative and the system is reflex, the affected individual may be unaware of dysfunction. The resultant dangers to aerial applicators are discussed, particularly with respect to atropine, which is necessary in the therapy of organophosphate and carbamate poisoning but is potentially harmful if self-administered for either prophylaxis or treatment. |
| Descriptores (primarios) |
efectos neurotóxicos; trastornos de la función visual; pesticidas; médicamentos; compuestos organofosforados |
| Descriptores (secundarios) |
escopolamina; mevinfós; fisostigmina; contraindicación; aviones; protección de los cultivos; investigaciones en el animal; atropina |
| Tipo de documento |
- |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Agricultural chemicals
Diseases of the eye and vision damage
Diseases of the nervous system
|
