| ID (ISN) del documento | 25154 |
| Número CIS |
76-1018 |
| ISSN - Título de la serie |
0041-008X - Toxicology and Applied Pharmacology |
| Año |
1975 |
| Número de serie |
|
| Autor(es) |
Paulet G., Roncin G., Vidal E., Toulouse P., Dassonville J. |
| Título |
Fluorocarbons and general metabolism in the rat, rabbit and dog. |
| Información bibliográfica |
Nov. 1975, Vol.34, No.2, p.197-203. 11 ref. |
| Resumen |
The metabolic effects of the inhalation of monofluorotrichloromethane (FC11) and difluorodichloromethane (FC12) were studied in various animal species, both in single exposure and repeated exposure experiments. The results are presented in tabular form and discussed. FC12 at 20% in a single exposure or at 5% in prolonged exposure (15 days) does not induce metabolic reactions. The same is true for FC11 at 2.5%; however, FC11 at 5% does produce significant effects which can be explained by a slowing down of cellular oxidation. With FC11/FC12 mixtures, the effects are clearly due to the presence of FC11. |
| Descriptores (primarios) |
hidrocarburos fluorados; perturbaciones metabólicas; toxicología |
| Descriptores (secundarios) |
diclorodifluorometano; investigaciones en el animal; inhalación; triclorofluorometano |
| Tipo de documento |
- |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Fluorocarbons
Endocrine diseases
Halogenated hydrocarbons
|
