| ID (ISN) del documento | 24987 |
| Número CIS |
76-762 |
| ISSN - Título de la serie |
0300-483X - Toxicology |
| Año |
1975 |
| Número de serie |
|
| Autor(es) |
Davidson P.P. |
| Título |
Dietary fat alteration of plasma cholinesterase response to malathion. |
| Información bibliográfica |
Sep. 1975, Vol.5, No.1, p.113-115. 4 ref. |
| Resumen |
Male rats were fed fat-free, normal-fat, and high-fat test diets. Sub-acute doses of malathion were given subcutaneously and cholinesterase levels were determined. Malathion was chosen because it is the least toxic of the organophosphate cholinesterase-inhibiting pesticides. Statistical analysis of the data showed that malathion inhibits blood cholinesterase to the greatest degree in normal-fat diet animals, with the least effect on high-fat groups, and fat-free subjects fall in between the two groups. An impressive increase in plasma cholinesterase activity was induced by the fat-free diet prior to malathion dosing, an unexpected effect. |
| Descriptores (primarios) |
compuestos organofosforados; colinesterasa; malatión; toxicología; pesticidas |
| Descriptores (secundarios) |
investigaciones en el animal |
| Tipo de documento |
- |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Esters and salts
Agricultural chemicals
|
