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Base de datos CISDOC

ID (ISN) del documento24051
Número CIS 75-1942
ISSN - Título de la serie 0041-008X - Toxicology and Applied Pharmacology
Año 1975
Número de serie
Autor(es) Rider J.A., Puletti E.J., Swader J.I.
Título The minimal oral toxicity level for mevinphos in man.
Información bibliográfica Apr. 1975, Vol.32, No.1, p.97-100. Illus. 4 ref.
Resumen To determine the safe exposure level for organophosphate insecticide, mevinphos (2-carbomethoxy-1-methylvinyl dimethyl phosphate) was fed to human volunteers for 30 days. The depression of cholinesterase activity was used as the criterion. None of the 1.0, 1.5, 2.0, or 2.5mg daily doses affected plasma cholinesterase. The 1.0mg had no effect; 1.5 and 2.0mg produced a 20% or greater decrease in erythrocyte cholinesterase on one occasion, whilst 2.5mg produced a steady decrease. It appears that this amount is the level of minimal incipient toxicity.
Descriptores (primarios) mevinfós; colinesterasa; toxicología; insecticidas; alteraciones enzimáticas
Descriptores (secundarios) ésteres del ácido fosfórico; investigaciones sobre el hombre; valoración de la toxicidad; ingestión
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Blood diseases
Esters and salts