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Base de datos CISDOC

ID (ISN) del documento23435
Número CIS 75-1368
ISSN - Título de la serie 0009-9309 - Clinical Toxicology
Año 1974
Número de serie
Autor(es) Wills J.H., Coulston F., Harris E.S., McChesney E.W., Russell J.C., Serrone D.M.
Título Inhalation of aerosolized ethylene glycol by man.
Información bibliográfica Oct. 1974, Vol.7, No.5, p.463-476. Illus. 27 ref.
Resumen After a brief review of the literature and a description of the signs and symptoms observed after experimental ethylene glycol ingestion, the authors present their own experiments in humans, in which 19 male volunteers were exposed to aerosolized ethylene glycol in mean daily concentrations of 3-67mg/m3 almost continually for 4 weeks. Blood and urine examinations gave no evidence of the absorption of important quantities of ethylene glycol. There were no serious signs of toxicity but some complaints of irritation of the upper respiratory tract. Irritation became common with an ethylene glycol concentration of 140mg/m3, and more than 200mg/m3 was intolerable. It was concluded that an individual with normal sensory apparatus could not absorb a harmful quantity of ethylene glycol through the respiratory tract. Detailed results of laboratory and psychometric tests are given in tables.
Descriptores (primarios) etilenglicol; toxicidad por inhalación; toxicología
Descriptores (secundarios) irritación; investigaciones sobre el hombre; aerosoles
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Glycols
Alcohols