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Base de datos CISDOC

ID (ISN) del documento22664
Número CIS 75-472
ISSN - Título de la serie 0013-2268 - Egészségtudomány
Año 1974
Número de serie
Autor(es) Trinh Van Bao, Szabó I., Ruzicska P., Czeizel E.
Título Chromosome studies in persons poisoned with phosphoric acid esters (pesticides)
Título original Kromoszóma-vizsgálatok heveny foszforsav-észter (peszticid) mérgezettekben [en húngaro]
Información bibliográfica 1974, Vol.18, No.4, p.348-360. Illus. 26 ref.
Resumen Results of chromosome studies performed on cultures of peripheral blood from persons suffering from acute phosphoric acid ester poisoning. Blood samples had been taken both during the period of intoxication and 1 and 6 months later. The rate of chromatid breaks, acentric fragments and stable chromosome aberrations (deletions, translocations) was significantly high during the intoxication phase and 1 month later. No definite correlation was found between the frequency of chromosome alterations and the severity of clinical manifestations. Chromosome aberrations were most frequent in cases of thiophosphate poisoning.
Descriptores (primarios) ésteres del ácido fosfórico; cambios cromosómicos; toxicología; pesticidas
Descriptores (secundarios) envenenamiento agudo; pruebas in vitro; observación de larga duración; tiofosfatos orgánicos
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Esters and salts