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Base de datos CISDOC

ID (ISN) del documento22572
Número CIS 75-507
ISSN - Título de la serie 0040-6376 - Thorax
Año 1974
Número de serie
Autor(es) Smith P., Heath D.
Título Paraquat lung: a reappraisal.
Información bibliográfica Nov. 1974, Vol.29, No.6, p.643-653. Illus. 20 ref.
Resumen Poisoning by paraquat commonly leads to the development of pulmonary fibrosis often described as being interstitial in nature and regarded by many as an example of fibrosing alveolitis. However, the experimental evidence from rats, together with observations on 4 human cases presented here, suggest that the basic pathological change in the human lung due to paraquat poisoning is a diffuse, cellular intra-alveolar fibrosis and not fibrosing alveolitis. It is shown to be associated with pulmonary vascular pathology. In assessing the histopathology of the lung in paraquat poisoning, a history of oxygen therapy must be taken into account as prolonged exposure to this gas may in itself induce pulmonary fibrosis.
Descriptores (primarios) herbicidas; histopatología; fibrosis pulmonar; paraquat
Descriptores (secundarios) estudio de caso; oxígeno; investigaciones en el animal; paraquat-cloruro
Tipo de documento -
Tema(s) Agricultura, pesca, cría de ganado
Broad subject area(s)
Navegación por categoria(s) Agricultural chemicals
Diseases of the respiratory system (except for pneumoconiosis & similar)
Heterocyclic compounds